Insulators: exploiting transcriptional and epigenetic mechanisms - Test2 - elhamkhani - TriplyDB

Insulators: exploiting transcriptional and epigenetic mechanisms

Insulators: exploiting transcriptional and epigenetic mechanisms

http://www.wikidata.org/entity/Q28257767

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Context differences reveal insulator and activator functions of a Su(Hw) binding region What does our genome encode?Regulation of major histocompatibility complex class II genes Architectural roles of multiple chromatin insulators at the human apolipoprotein gene cluster The accessible chromatin landscape of the human genome Silencing by imprinted noncoding RNAs: is transcription the answer?Mediation of CTCF transcriptional insulation by DEAD-box RNA-binding protein p68 and steroid receptor RNA activator SRA Condensin and cohesin complexity: the expanding repertoire of functions CTCF: master weaver of the genome CTCFBSDB: a CTCF-binding site database for characterization of vertebrate genomic insulators Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains Gene therapy for severe combined immunodeficiency: are we there yet?Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites The Role of Gammaherpesviruses in Cancer Pathogenesis An Overview of Genome Organization and How We Got There: from FISH to Hi-C A comparison of herpes simplex virus type 1 and varicella-zoster virus latency and reactivation Facioscapulohumeral muscular dystrophy: consequences of chromatin relaxation Roles of chromatin insulators in the formation of long-range contacts Transgenic mice for intersectional targeting of neural sensors and effectors with high specificity and performance.Chromatin Insulator Factors Involved in Long-Range DNA Interactions and Their Role in the Folding of the Drosophila Genome Retroviral vectors and transposons for stable gene therapy: advances, current challenges and perspectives MyoD regulates p57kip2 expression by interacting with a distant cis-element and modifying a higher order chromatin structure Genome-wide and parental allele-specific analysis of CTCF and cohesin DNA binding in mouse brain reveals a tissue-specific binding pattern and an association with imprinted differentially methylated regions Association of new deletion/duplication region at chromosome 1p21 with intellectual disability, severe speech deficit and autism spectrum disorder-like behavior: an all-in approach to solving the DPYD enigma MIR retrotransposon sequences provide insulators to the human genome Efficient isolation of specific genomic regions retaining molecular interactions by the iChIP system using recombinant exogenous DNA-binding proteins Exaptation of transposable elements into novel cis-regulatory elements: is the evidence always strong?Drosophila errantiviruses Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients Direct identification of insulator components by insertional chromatin immunoprecipitation Globin genes on the move A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping Single-molecule approaches to probe the structure, kinetics, and thermodynamics of nucleoprotein complexes that regulate transcription.Alterations in cardiac DNA methylation in human dilated cardiomyopathy Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling.Predicting expression: the complementary power of histone modification and transcription factor binding data.Comprehensive identification and annotation of cell type-specific and ubiquitous CTCF-binding sites in the human genome.Transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects : Insect insulator proteins.Evolutionary genomic remodelling of the human 4q subtelomere (4q35.2).CTCF genomic binding sites in Drosophila and the organisation of the bithorax complex

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Insulators: exploiting transcriptional and epigenetic mechanisms

http://www.wikidata.org/entity/Q28257767

description

2006 nî lūn-bûn

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2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Insulators: exploiting transcriptional and epigenetic mechanisms

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Insulators: exploiting transcriptional and epigenetic mechanisms

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Insulators: exploiting transcriptional and epigenetic mechanisms

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Insulators: exploiting transcriptional and epigenetic mechanisms

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Insulators: exploiting transcriptional and epigenetic mechanisms

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Insulators: exploiting transcriptional and epigenetic mechanisms

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prefLabel

Insulators: exploiting transcriptional and epigenetic mechanisms

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Insulators: exploiting transcriptional and epigenetic mechanisms

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Insulators: exploiting transcriptional and epigenetic mechanisms

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Nature Reviews Genetics

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Insulators: exploiting transcriptional and epigenetic mechanisms

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Gary Felsenfeld

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Miklos Gaszner

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P2860

Interchromosomal associations between alternatively expressed loci

An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes

RNA polymerase III and RNA polymerase II promoter complexes are heterochromatin barriers in Saccharomyces cerevisiae

Conserved CTCF insulator elements flank the mouse and human beta-globin loci

Chip, a widely expressed chromosomal protein required for segmentation and activity of a remote wing margin enhancer in Drosophila

Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association.

The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

CTCF, a candidate trans-acting factor for X-inactivation choice

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scholarly article

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10.1038/NRG1925

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