Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling
about
The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complexRegulation of TopBP1 oligomerization by Akt/PKB for cell survivalDNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domainsSTRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domainsFunctional Evolution of BRCT Domains from Binding DNA to ProteinBRCT domains: easy as one, two, threeStructural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1Evolutionary conservation analysis increases the colocalization of predicted exonic splicing enhancers in the BRCA1 gene with missense sequence changes and in-frame deletions, but not polymorphismsBACH1 Ser919Pro variant and breast cancer risk.A guide for functional analysis of BRCA1 variants of uncertain significancePhosphopeptide interactions with BRCA1 BRCT domains: More than just a motifSolution Structure of Polymerase μ's BRCT Domain Reveals an Element Essential for Its Role in Nonhomologous End Joining †Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approachStructure of a Second BRCT Domain Identified in the Nijmegen Breakage Syndrome Protein Nbs1 and its Function in an MDC1-Dependent Localization of Nbs1 to DNA Damage SitesThe Structure of Fcp1, an Essential RNA Polymerase II CTD PhosphataseA Pocket on the Surface of the N-Terminal BRCT Domain of Mcph1 Is Required to Prevent Abnormal Chromosome CondensationStructure of the DNA-bound BRCA1 C-terminal Region from Human Replication Factor C p140 and Model of the Protein-DNA ComplexStructure and function of the Rad9-binding region of the DNA-damage checkpoint adaptor TopBP1Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint controlImpact of BRCA1 BRCT Domain Missense Substitutions on Phosphopeptide RecognitionDual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1Molecular Basis for the Association of Microcephalin (MCPH1) Protein with the Cell Division Cycle Protein 27 (Cdc27) Subunit of the Anaphase-promoting ComplexStructure of C-terminal Tandem BRCT Repeats of Rtt107 Protein Reveals Critical Role in Interaction with Phosphorylated Histone H2A during DNA Damage RepairStructural Insights into Recognition of MDC1 by TopBP1 in DNA Replication Checkpoint ControlPhosphorylation-Dependent Assembly and Coordination of the DNA Damage Checkpoint Apparatus by Rad4TopBP1Peptide library approach to uncover phosphomimetic inhibitors of the BRCA1 C-terminal domainMechanism of PhosphoThreonine/Serine Recognition and Specificity for Modular Domains from All-atom Molecular DynamicsFunctional impact of missense variants in BRCA1 predicted by supervised learningCharacterization of Promiscuous Binding of Phosphor Ligands to Breast-Cancer-Gene 1 (BRCA1) C-Terminal (BRCT): Molecular Dynamics, Free Energy, Entropy and Inhibitor DesignBRCT domains: A little more than kin, and less than kindHigh occurrence of BRCA1 intragenic rearrangements in hereditary breast and ovarian cancer syndrome in the Czech Republic.Rtt107/Esc4 binds silent chromatin and DNA repair proteins using different BRCT motifs.FANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein.Dual-fluorophore quantitative high-throughput screen for inhibitors of BRCT-phosphoprotein interactionCharting the landscape of tandem BRCT domain-mediated protein interactions.The BRCA1-interacting protein Abraxas is required for genomic stability and tumor suppression.Determination of cancer risk associated with germ line BRCA1 missense variants by functional analysis.BRCA1-directed, enhanced and aberrant homologous recombination: mechanism and potential treatment strategies.TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint.
P2860
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P2860
Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling
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2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
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2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Structure of the BRCT repeats ...... de: implications for signaling
@ast
Structure of the BRCT repeats ...... de: implications for signaling
@en
Structure of the BRCT repeats ...... de: implications for signaling
@nl
type
label
Structure of the BRCT repeats ...... de: implications for signaling
@ast
Structure of the BRCT repeats ...... de: implications for signaling
@en
Structure of the BRCT repeats ...... de: implications for signaling
@nl
prefLabel
Structure of the BRCT repeats ...... de: implications for signaling
@ast
Structure of the BRCT repeats ...... de: implications for signaling
@en
Structure of the BRCT repeats ...... de: implications for signaling
@nl
P1433
P1476
Structure of the BRCT repeats ...... de: implications for signaling
@en
P2093
Eric N Shiozaki
Lichuan Gu
P304
P407
P577
2004-05-07T00:00:00Z