The role of mu opioid receptor desensitization and endocytosis in morphine tolerance and dependence
about
Single dose of morphine produced a prolonged effect on dopamine neuron activitiesMOR is not enough: identification of novel mu-opioid receptor interacting proteins using traditional and modified membrane yeast two-hybrid screensThe analgesic efficacy of fentanyl: relationship to tolerance and mu-opioid receptor regulationInvolvement of Mammalian RF-Amide Peptides and Their Receptors in the Modulation of Nociception in RodentsCell-autonomous regulation of Mu-opioid receptor recycling by substance P.Imaging of kiss-and-run exocytosis of surface receptors in neuronal cultures.Opioid-receptor-heteromer-specific trafficking and pharmacology.Rapid delivery of internalized signaling receptors to the somatodendritic surface by sequence-specific local insertion.Opioid rotation in clinical practice.μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization.Opioid-induced mitogen-activated protein kinase signaling in rat enteric neurons following chronic morphine treatment.Chronic Δ⁹-tetrahydrocannabinol treatment in rhesus monkeys: differential tolerance and cross-tolerance among cannabinoidsProlonged morphine treatment alters δ opioid receptor post-internalization traffickingUsing the Phenogen website for 'in silico' analysis of morphine-induced analgesia: identifying candidate genes.Melatonin prevents morphine-induced hyperalgesia and tolerance in rats: role of protein kinase C and N-methyl-D-aspartate receptors.Association of OPRM1 A118G variant with risk of morphine-induced respiratory depression following spine fusion in adolescents.Ubiquitination in the first cytoplasmic loop of μ-opioid receptors reveals a hierarchical mechanism of lysosomal down-regulation.Chronic methadone treatment shows a better cost/benefit ratio than chronic morphine in mice.Experimental psychiatric illness and drug abuse models: from human to animal, an overviewGRK2 protein-mediated transphosphorylation contributes to loss of function of μ-opioid receptors induced by neuropeptide FF (NPFF2) receptors.Fast modulation of μ-opioid receptor (MOR) recycling is mediated by receptor agonists.Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons.Multiple inhibitory G-protein-coupled receptors resist acute desensitization in the presynaptic but not postsynaptic compartments of neuronsTolerance and sensitization to chronic escalating dose heroin following extended withdrawal in Fischer rats: possible role of mu-opioid receptors.Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.Differentiation of opioid drug effects by hierarchical multi-site phosphorylationQuantitative encoding of the effect of a partial agonist on individual opioid receptors by multisite phosphorylation and threshold detection.Ligand-induced μ opioid receptor internalization in enteric neurons following chronic treatment with the opiate fentanylDivergent modes for cargo-mediated control of clathrin-coated pit dynamicsHydromorphone efficacy and treatment protocol impact on tolerance and mu-opioid receptor regulation.Molecular Pharmacology of δ-Opioid Receptors.D-serine in the midbrain periaqueductal gray contributes to morphine tolerance in rats.Methadone Reverses Analgesic Tolerance Induced by Morphine Pretreatment.Downregulation of miR-219 enhances brain-derived neurotrophic factor production in mouse dorsal root ganglia to mediate morphine analgesic tolerance by upregulating CaMKIIγ.Bidirectional effects of fentanyl on dendritic spines and AMPA receptors depend upon the internalization of mu opioid receptorsMorphine Protects Spinal Cord Astrocytes from Glutamate-Induced Apoptosis via Reducing Endoplasmic Reticulum Stress.Role of µ-opioid receptor reserve and µ-agonist efficacy as determinants of the effects of µ-agonists on intracranial self-stimulation in ratsEndocytic profiles of δ-opioid receptor ligands determine the duration of rapid but not sustained cAMP responses.Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery.miR-365 targets β-arrestin 2 to reverse morphine tolerance in rats.
P2860
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P2860
The role of mu opioid receptor desensitization and endocytosis in morphine tolerance and dependence
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The role of mu opioid receptor ...... phine tolerance and dependence
@ast
The role of mu opioid receptor ...... phine tolerance and dependence
@en
The role of mu opioid receptor ...... phine tolerance and dependence
@nl
type
label
The role of mu opioid receptor ...... phine tolerance and dependence
@ast
The role of mu opioid receptor ...... phine tolerance and dependence
@en
The role of mu opioid receptor ...... phine tolerance and dependence
@nl
prefLabel
The role of mu opioid receptor ...... phine tolerance and dependence
@ast
The role of mu opioid receptor ...... phine tolerance and dependence
@en
The role of mu opioid receptor ...... phine tolerance and dependence
@nl
P921
P3181
P1476
The role of mu opioid receptor ...... phine tolerance and dependence
@en
P2093
Jennifer L Whistler
Lene Martini
P304
P3181
P356
10.1016/J.CONB.2007.10.004
P407
P577
2007-10-01T00:00:00Z