Age-associated mitochondrial DNA mutations lead to small but significant changes in cell proliferation and apoptosis in human colonic crypts
about
Deficient expression of DNA repair enzymes in early progression to sporadic colon cancerAging of the mammalian gastrointestinal tract: a complex organ systemCancer and age related colonic crypt deficiencies in cytochrome c oxidase IThe road to rack and ruin: selecting deleterious mitochondrial DNA variantsClonal expansion of early to mid-life mitochondrial DNA point mutations drives mitochondrial dysfunction during human ageing.Passenger mutations as a marker of clonal cell lineages in emerging neoplasiaSensitivity to low-dose/low-LET ionizing radiation in mammalian cells harboring mutations in succinate dehydrogenase subunit C is governed by mitochondria-derived reactive oxygen speciesThe importance of mitochondrial DNA in aging and cancer.Human stem cell aging: do mitochondrial DNA mutations have a causal role?Umbilical cord mesenchymal stromal cells affected by gestational diabetes mellitus display premature aging and mitochondrial dysfunctionCell lineage tracing in human epithelial tissues using mitochondrial DNA mutations as clonal markers.Mechanisms linking mtDNA damage and aging.Mitochondrial DNA polymerase editing mutation, PolgD257A, disturbs stem-progenitor cell cycling in the small intestine and restricts excess fat absorptionEffects of aging on apoptosis gene expression in oral mucosal tissues.Reduced intestinal lipid absorption and body weight-independent improvements in insulin sensitivity in high-fat diet-fed Park2 knockout mice.Stress and stem cells.Stem cell identification--in vivo lineage analysis versus in vitro isolation and clonal expansion.Underlying role of mitochondrial mutagenesis in the pathogenesis of a disease and current approaches for translational research.The Barrett's Gland in Phenotype Space.The human urothelium consists of multiple clonal units, each maintained by a stem cell.Nutrition and ageing: knowledge, gaps and research priorities.Mitochondrial DNA alteration in primary and metastatic colorectal cancer: Different frequency and association with selected clinicopathological and molecular markers.Roles of Mitochondrial DNA Mutations in Stem Cell Ageing.Neuroendocrine and proliferative potential of human intestinal cells during aging.
P2860
Q21195898-AA6E6F59-9637-4F0F-B874-E33A93B9ED09Q26823914-B157463C-EF31-4045-BA9B-9C1FDDD1AFB7Q28301988-43BBFAE9-0713-4B06-8A9A-A126E1BBB3FCQ33655994-38D58363-1559-47AD-8F6D-17D335FD0E50Q34213867-E52D7176-214B-4877-B1D4-F070A4F6AF0DQ34361056-4EA8D469-BAE1-4F28-9DD8-ED609E603714Q34822379-CC6420F5-0D43-443A-A09A-6FC5FCD6C5C4Q34974582-8B21EA25-98D0-47E6-89A3-A0E4F5E38926Q35093139-4F167AD4-382D-4C5B-BD3B-D7C9916A9018Q35097799-65324E0C-DCED-4368-B0C2-D57D1291C7B8Q35753762-144C696A-9E7D-44E4-96E8-A9C8F5AFE15DQ35868104-465E233F-1E82-46D9-9B07-EABB93C53AB1Q35994011-E9AF8C7B-0E2F-4C98-A5AC-CF141806568DQ36670054-ECABAFA8-2BB6-4A1C-9367-F9C630352143Q37139415-CC840866-73D9-4657-BDAF-7A51813722BEQ37267831-CF29F106-3B7E-4614-940C-35E19781DFC4Q37992588-19A8B54D-8163-4AA8-A495-03D20EA5B027Q39000027-EBFFD195-0AD6-4387-9373-A9F2EE006FECQ39100481-28254B27-544F-43BB-A213-FD5D1E3481F6Q42491329-76F00D67-C845-4B5B-A66F-F3FB24C48416Q48215575-C88FDF93-B35E-4FC2-BDC0-4B032DA97E3BQ51084286-BDB70B5A-75FE-499B-B6FA-395E91736168Q51759033-C3B9F558-F788-432B-B2B9-EB3813CCE75FQ53192982-EECDEBBE-6C51-4349-B6F3-F7FF5BA3EA96
P2860
Age-associated mitochondrial DNA mutations lead to small but significant changes in cell proliferation and apoptosis in human colonic crypts
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Age-associated mitochondrial D ...... ptosis in human colonic crypts
@ast
Age-associated mitochondrial D ...... ptosis in human colonic crypts
@en
Age-associated mitochondrial D ...... ptosis in human colonic crypts
@nl
type
label
Age-associated mitochondrial D ...... ptosis in human colonic crypts
@ast
Age-associated mitochondrial D ...... ptosis in human colonic crypts
@en
Age-associated mitochondrial D ...... ptosis in human colonic crypts
@nl
prefLabel
Age-associated mitochondrial D ...... ptosis in human colonic crypts
@ast
Age-associated mitochondrial D ...... ptosis in human colonic crypts
@en
Age-associated mitochondrial D ...... ptosis in human colonic crypts
@nl
P2093
P2860
P50
P921
P1433
P1476
Age-associated mitochondrial D ...... ptosis in human colonic crypts
@en
P2093
Laura C Greaves
Marco Nooteboom
Riem Johnson
Robert N Lightowlers
Robert W Taylor
P2860
P356
10.1111/J.1474-9726.2009.00531.X
P407
P577
2010-02-01T00:00:00Z