Reduction in the developmental potential of intrathymic T cell progenitors with age
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The effect of age on thymic functionImmunosenescence: emerging challenges for an ageing populationImmunosenescence and vaccination.Changes in primary lymphoid organs with agingGenetic regulation of thymocyte progenitor agingT cell ageing: effects of age on development, survival & functionImmunosenescence: deficits in adaptive immunity in the elderlyDeletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell lossEnhancing T lineage production in aged mice: a novel function of Foxn1 in the bone marrow nicheFoxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive mannerDeclining expression of a single epithelial cell-autonomous gene accelerates age-related thymic involutionThymic fatness and approaches to enhance thymopoietic fitness in aging.Is thymocyte development functional in the aged?CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymusA quantitative trait locus on chr.4 regulates thymic involution.Aging of the T cell compartment in mice and humans: from no naive expectations to foggy memories.Prolongevity hormone FGF21 protects against immune senescence by delaying age-related thymic involutionExpression of p16(INK4a) prevents cancer and promotes aging in lymphocytes.Manifestations and mechanisms of stem cell aging.Emerging strategies to boost thymic functionEnhanced hematopoietic stem cell function mediates immune regeneration following sex steroid blockade.RhoB deficiency in thymic medullary epithelium leads to early thymic atrophyMCL1 increases primitive thymocyte viability in female mice and promotes thymic expansion into adulthoodThe expansion of thymopoiesis in neonatal mice is dependent on expression of high mobility group a 2 protein (Hmga2).Overexpression of Foxn1 attenuates age-associated thymic involution and prevents the expansion of peripheral CD4 memory T cellsSustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of agingYoung, proliferative thymic epithelial cells engraft and function in aging thymuses.Transforming growth factor-beta2 is involved in quantitative genetic variation in thymic involution.Keratinocyte growth factor (KGF) is required for postnatal thymic regeneration.Mouse plasmacytoid dendritic cells derive exclusively from estrogen-resistant myeloid progenitorsMechanisms of immunosenescence: lessons from models of accelerated immune aging.Multiple prethymic defects underlie age-related loss of T progenitor competenceGhrelin promotes thymopoiesis during agingThymus Size and Age-related Thymic Involution: Early Programming, Sexual Dimorphism, Progenitors and Stroma.Fibroblast growth factor-7 partially reverses murine thymocyte progenitor aging by repression of Ink4a.Effects of aging on early B- and T-cell development.T cell immune reconstitution following lymphodepletion.Premature thymic involution is independent of structural plasticity of the thymic stroma.Aging induced decline in T-lymphopoiesis is primarily dependent on status of progenitor niches in the bone marrow and thymusFrom stem cell to T cell: one route or many?
P2860
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P2860
Reduction in the developmental potential of intrathymic T cell progenitors with age
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Reduction in the developmental potential of intrathymic T cell progenitors with age
@ast
Reduction in the developmental potential of intrathymic T cell progenitors with age
@en
Reduction in the developmental potential of intrathymic T cell progenitors with age
@nl
type
label
Reduction in the developmental potential of intrathymic T cell progenitors with age
@ast
Reduction in the developmental potential of intrathymic T cell progenitors with age
@en
Reduction in the developmental potential of intrathymic T cell progenitors with age
@nl
prefLabel
Reduction in the developmental potential of intrathymic T cell progenitors with age
@ast
Reduction in the developmental potential of intrathymic T cell progenitors with age
@en
Reduction in the developmental potential of intrathymic T cell progenitors with age
@nl
P2093
P1476
Reduction in the developmental potential of intrathymic T cell progenitors with age
@en
P2093
Encarnacion Montecino-Rodriguez
Hyeyoung Min
Kenneth Dorshkind
P304
P356
10.4049/JIMMUNOL.173.1.245
P407
P577
2004-07-01T00:00:00Z