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Prediction of protein binding regions in disordered proteinsHistone H1 recruitment by CHD8 is essential for suppression of the Wnt-β-catenin signaling pathwayDecoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complexAn intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acidTargeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signalingWnt signaling: the good and the badThe many faces and functions of β-cateninCell-context dependent TCF/LEF expression and function: alternative tales of repression, de-repression and activation potentialsCrystal Structure of the HEAT Domain from the Pre-mRNA Processing Factor SymplekinInhibition of oncogenic Wnt signaling through direct targeting of -cateninStructural basis of coactivation of liver receptor homolog-1 by -cateninHelical Repeat Structure of Apoptosis Inhibitor 5 Reveals Protein-Protein Interaction ModulesStructural and Thermodynamic Characterization of Cadherin{middle dot} -Catenin{middle dot} -Catenin Complex FormationExploiting tertiary structure through local folds for crystallographic phasingInteractions between Casein kinase Iepsilon (CKIepsilon) and two substrates from disparate signaling pathways reveal mechanisms for substrate-kinase specificityStructural basis for the recognition of Asef by adenomatous polyposis coli.The function of BCL9 in Wnt/beta-catenin signaling and colorectal cancer cells.NF2-deficient cells depend on the Rac1-canonical Wnt signaling pathway to promote the loss of contact inhibition of proliferation.SAR405838: an optimized inhibitor of MDM2-p53 interaction that induces complete and durable tumor regressionWnt signalling induces accumulation of phosphorylated β-catenin in two distinct cytosolic complexes.Methods for SAXS-based structure determination of biomolecular complexes.BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells.Cytoskeletal mechanisms regulating vascular endothelial barrier function in response to acute lung injuryFunctional inhibition of β-catenin-mediated Wnt signaling by intracellular VHH antibodiesNuclear signaling from cadherin adhesion complexesTranscriptional regulation in Saccharomyces cerevisiae: transcription factor regulation and function, mechanisms of initiation, and roles of activators and coactivators.Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cellsDesign of triazole-stapled BCL9 α-helical peptides to target the β-catenin/B-cell CLL/lymphoma 9 (BCL9) protein-protein interaction.Architecture of the trypanosome RNA editing accessory complex, MRB1.An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP.β-Catenin Upregulates the Constitutive and Virus-Induced Transcriptional Capacity of the Interferon Beta Promoter through T-Cell Factor Binding SitesBCL9/9L-β-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer.Local sequence assembly reveals a high-resolution profile of somatic structural variations in 97 cancer genomes.Ligand binding by repeat proteins: natural and designed.Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemiaRole of BCL9L in transforming growth factor-β (TGF-β)-induced epithelial-to-mesenchymal-transition (EMT) and metastasis of pancreatic cancer.Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling.Drugging Wnt signalling in cancermiR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/β-catenin/BCL9 pathway.Discovery of small molecule inhibitors of the Wnt/β-catenin signaling pathway by targeting β-catenin/Tcf4 interactions.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Crystal structure of a beta-catenin/BCL9/Tcf4 complex
@ast
Crystal structure of a beta-catenin/BCL9/Tcf4 complex
@en
Crystal structure of a beta-catenin/BCL9/Tcf4 complex
@nl
type
label
Crystal structure of a beta-catenin/BCL9/Tcf4 complex
@ast
Crystal structure of a beta-catenin/BCL9/Tcf4 complex
@en
Crystal structure of a beta-catenin/BCL9/Tcf4 complex
@nl
prefLabel
Crystal structure of a beta-catenin/BCL9/Tcf4 complex
@ast
Crystal structure of a beta-catenin/BCL9/Tcf4 complex
@en
Crystal structure of a beta-catenin/BCL9/Tcf4 complex
@nl
P2093
P3181
P1433
P1476
Crystal structure of a beta-catenin/BCL9/Tcf4 complex
@en
P2093
Caroline L Dahlberg
David Kimelman
James Sampietro
Thomas R Hinds
Uhn Soo Cho
P304
P3181
P356
10.1016/J.MOLCEL.2006.09.001
P407
P50
P577
2006-10-20T00:00:00Z