Upregulation of pleiotrophin gene expression in developing microvasculature, macrophages, and astrocytes after acute ischemic brain injury
about
Pleiotrophin signals increased tyrosine phosphorylation of beta beta-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase beta/zetaPleiotrophin (PTN) is expressed in vascularized human atherosclerotic plaques: IFN-{gamma}/JAK/STAT1 signaling is critical for the expression of PTN in macrophages.Behavioral and neuroanatomical abnormalities in pleiotrophin knockout mice.Pleiotrophin regulates serine phosphorylation and the cellular distribution of beta-adducin through activation of protein kinase CThe role of pleiotrophin and beta-catenin in fetal lung development.Expression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia.Pleiotrophin is a neurotrophic factor for spinal motor neurons.Gene expression suggests spontaneously hypertensive rats may have altered metabolism and reduced hypoxic toleranceGenes that distinguish physiological and pathological angiogenesisA dominant-negative pleiotrophin mutant introduced by homologous recombination leads to germ-cell apoptosis in male mice.Pleiotrophin induces transdifferentiation of monocytes into functional endothelial cellsPleiotrophin regulates the expansion and regeneration of hematopoietic stem cellsPleiotrophin suppression of receptor protein tyrosine phosphatase-β/ζ maintains the self-renewal competence of fetal human oligodendrocyte progenitor cells.Toll-like receptor signaling in endogenous neuroprotection and stroke.VEGF and pleiotrophin modulate the immune profile of breast cancer.Pleiotrophin regulates lung epithelial cell proliferation and differentiation during fetal lung development via beta-catenin and Dlk1.From top to bottom: midkine and pleiotrophin as emerging players in immune regulation.Pleiotrophin induces nitric oxide dependent migration of endothelial progenitor cells.Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis.A novel quantification-driven proteomic strategy identifies an endogenous peptide of pleiotrophin as a new biomarker of Alzheimer's disease.Development of inhibitors of receptor protein tyrosine phosphatase β/ζ (PTPRZ1) as candidates for CNS disorders.Pleiotrophin, a multifunctional cytokine and growth factor, induces leukocyte responses through the integrin Mac-1.Cyclin-dependent kinase 5 mediates pleiotrophin-induced endothelial cell migration.
P2860
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P2860
Upregulation of pleiotrophin gene expression in developing microvasculature, macrophages, and astrocytes after acute ischemic brain injury
description
1998 nî lūn-bûn
@nan
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Upregulation of pleiotrophin g ...... er acute ischemic brain injury
@ast
Upregulation of pleiotrophin g ...... er acute ischemic brain injury
@en
Upregulation of pleiotrophin g ...... er acute ischemic brain injury
@nl
type
label
Upregulation of pleiotrophin g ...... er acute ischemic brain injury
@ast
Upregulation of pleiotrophin g ...... er acute ischemic brain injury
@en
Upregulation of pleiotrophin g ...... er acute ischemic brain injury
@nl
prefLabel
Upregulation of pleiotrophin g ...... er acute ischemic brain injury
@ast
Upregulation of pleiotrophin g ...... er acute ischemic brain injury
@en
Upregulation of pleiotrophin g ...... er acute ischemic brain injury
@nl
P2093
P921
P1476
Upregulation of pleiotrophin g ...... er acute ischemic brain injury
@en
P2093
P304
P356
10.1523/JNEUROSCI.18-10-03699.1998
P407
P577
1998-05-01T00:00:00Z