Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment
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Beyond DNA repair: DNA-PK function in cancerGenotypic characteristics of resistant tumors to pre-operative ionizing radiation in rectal cancerTNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1ATM, ATR and DNA-PKcs expressions correlate to adverse clinical outcomes in epithelial ovarian cancersDNA-PK target identification reveals novel links between DNA repair signaling and cytoskeletal regulationNSCLC cells demonstrate differential mode of cell death in response to the combined treatment of radiation and a DNA-PKcs inhibitor.The Catalytic Subunit of DNA-Dependent Protein Kinase Coordinates with Polo-Like Kinase 1 to Facilitate Mitotic Entry.DNA-Dependent Protein Kinase As Molecular Target for Radiosensitization of Neuroblastoma Cells.DNA-PKcs Negatively Regulates Cyclin B1 Protein Stability through Facilitating Its Ubiquitination Mediated by Cdh1-APC/C Pathway.Doxycycline down-regulates DNA-PK and radiosensitizes tumor initiating cells: Implications for more effective radiation therapy.Novel kinase fusion transcripts found in endometrial cancerCommon cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition.Global Mapping of Traditional Chinese Medicine into Bioactivity Space and Pathways Annotation Improves Mechanistic Understanding and Discovers Relationships between Therapeutic Action (Sub)classes.Spontaneous tumor development in bone marrow-rescued DNA-PKcs(3A/3A) mice due to dysfunction of telomere leading strand deprotectionDNA double strand break repair via non-homologous end-joining.Deregulation of DNA-dependent protein kinase catalytic subunit contributes to human hepatocarcinogenesis development and has a putative prognostic value.DNA-PKcs activates the Chk2-Brca1 pathway during mitosis to ensure chromosomal stability.Targeting hyperactivated DNA-PKcs by KU0060648 inhibits glioma progression and enhances temozolomide therapy via suppression of AKT signaling.Differential radiosensitivity phenotypes of DNA-PKcs mutations affecting NHEJ and HRR systems following irradiation with gamma-rays or very low fluences of alpha particles.Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit.Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway.DNA-dependent protein kinase catalytic subunit functions in metastasis and influences survival in advanced-stage laryngeal squamous cell carcinomaDNA-PK Inhibition by NU7441 Enhances Chemosensitivity to Topoisomerase Inhibitor in Non-Small Cell Lung Carcinoma Cells by Blocking DNA Damage RepairStudies of lncRNAs in DNA double strand break repair: what is new?Expression of DNA-dependent protein kinase catalytic subunit in laryngeal squamous cell carcinoma and its importance.Integrated multi-omics data analysis identifying novel drug sensitivity-associated molecular targets of hepatocellular carcinoma cells.
P2860
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P2860
Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Role of DNA-dependent protein ...... ncer development and treatment
@ast
Role of DNA-dependent protein ...... ncer development and treatment
@en
Role of DNA-dependent protein ...... ncer development and treatment
@nl
type
label
Role of DNA-dependent protein ...... ncer development and treatment
@ast
Role of DNA-dependent protein ...... ncer development and treatment
@en
Role of DNA-dependent protein ...... ncer development and treatment
@nl
prefLabel
Role of DNA-dependent protein ...... ncer development and treatment
@ast
Role of DNA-dependent protein ...... ncer development and treatment
@en
Role of DNA-dependent protein ...... ncer development and treatment
@nl
P2093
P2860
P1476
Role of DNA-dependent protein ...... ncer development and treatment
@en
P2093
Benjamin P C Chen
Feng-Ming Hsu
Shichuan Zhang
P2860
P356
10.3978/J.ISSN.2218-676X.2012.04.01
P407
P577
2012-06-01T00:00:00Z