Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X-linked hypophosphatemia - Test2 - elhamkhani - TriplyDB

Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X-linked hypophosphatemia

Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X-linked hypophosphatemia

http://www.wikidata.org/entity/Q28275381

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Fibroblast Growth Factor 23: A New Dimension to Diseases of Calcium-Phosphorus Metabolism Extracellular matrix mineralization in periodontal tissues: Noncollagenous matrix proteins, enzymes, and relationship to hypophosphatasia and X-linked hypophosphatemia Osteocytes: master orchestrators of bone Excessive Osteocytic Fgf23 Secretion Contributes to Pyrophosphate Accumulation and Mineralization Defect in Hyp Mice A unified model for bone-renal mineral and energy metabolism PHEX mimetic (SPR4-peptide) corrects and improves HYP and wild type mice energy-metabolism Behavior of Human Osteoblast Cells Cultured on Titanium Discs in Relation to Surface Roughness and Presence of Melatonin.Hypophosphatemic rickets: revealing novel control points for phosphate homeostasis.Abnormal osteopontin and matrix extracellular phosphoglycoprotein localization, and odontoblast differentiation, in X-linked hypophosphatemic teeth.MEPE-derived ASARM peptide inhibits odontogenic differentiation of dental pulp stem cells and impairs mineralization in tooth models of X-linked hypophosphatemia The impairment of osteogenesis in bone sialoprotein (BSP) knockout calvaria cell cultures is cell density dependent.SPR4-peptide alters bone metabolism of normal and HYP mice.High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes.Age dependent regulation of bone-mass and renal function by the MEPE ASARM-motif Downregulation of PHEX in multibacillary leprosy patients: observational cross-sectional study.Current concepts in odontohypophosphatasia form of hypophosphatasia and report of two cases.Do ASARM peptides play a role in nephrogenic systemic fibrosis?Family with sequence similarity member 20C is the primary but not the only kinase for the small-integrin-binding ligand N-linked glycoproteins in bone Retinoic acid-induced premature osteoblast-to-preosteocyte transitioning has multiple effects on calvarial development.Multifunctional role of osteopontin in directing intrafibrillar mineralization of collagen and activation of osteoclasts.The rachitic tooth.Increased osteopontin contributes to inhibition of bone mineralization in FGF23-deficient mice.Therapeutic management of hypophosphatemic rickets from infancy to adulthood.Impaired urinary osteopontin excretion in Npt2a-/- mice.Mathematical model for bone mineralization.FGF23 regulates renal sodium handling and blood pressure.Effect of Phosphorylation on a Human-like Osteopontin Peptide.FGF23 Regulates Bone Mineralization in a 1,25(OH)2 D3 and Klotho-Independent Manner.Mineralization of dense collagen hydrogel scaffolds by human pulp cells.Osteopontin regulates dentin and alveolar bone development and mineralization.Defective Mineralization in X-Linked Hypophosphatemia Dental Pulp Cell Cultures.Impact of Conventional Medical Therapy on Bone Mineral Density and Bone Turnover in Adult Patients with X-Linked Hypophosphatemia: A 6-Year Prospective Cohort Study.Physiological Actions of Fibroblast Growth Factor-23.Phosphate and Vitamin D Prevent Periodontitis in X-Linked Hypophosphatemia Magnetic Resonance Imaging Features as Surrogate Markers of X-Linked Hypophosphatemic Rickets Activity

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P2860

Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X-linked hypophosphatemia

http://www.wikidata.org/entity/Q28275381

description

2013 nî lūn-bûn

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2013 թուականի Մարտին հրատարակուած գիտական յօդուած

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2013 թվականի մարտին հրատարակված գիտական հոդված

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2013年の論文

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Proteolytic processing of oste ...... l of X-linked hypophosphatemia

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Proteolytic processing of oste ...... l of X-linked hypophosphatemia

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Proteolytic processing of oste ...... l of X-linked hypophosphatemia

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Proteolytic processing of oste ...... l of X-linked hypophosphatemia

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Proteolytic processing of oste ...... l of X-linked hypophosphatemia

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Proteolytic processing of oste ...... l of X-linked hypophosphatemia

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Proteolytic processing of oste ...... l of X-linked hypophosphatemia

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Proteolytic processing of oste ...... l of X-linked hypophosphatemia

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Proteolytic processing of oste ...... l of X-linked hypophosphatemia

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Journal of Bone and Mineral Research

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Proteolytic processing of oste ...... l of X-linked hypophosphatemia

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Adriana K Carmona

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Betty Hoac

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Diego M Assis

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Marc D McKee

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Monzur Murshed

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Nilana M T Barros

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Raquel L Neves

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William N Addison

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P2860

MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia

Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23

FGF-23 inhibits renal tubular phosphate transport and is a PHEX substrate

A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. The HYP Consortium

Cloning of human PEX cDNA. Expression, subcellular localization, and endopeptidase activity

Human recombinant endopeptidase PHEX has a strict S1' specificity for acidic residues and cleaves peptides derived from fibroblast growth factor-23 and matrix extracellular phosphoglycoprotein

Post-translationally modified residues of native human osteopontin are located in clusters: identification of 36 phosphorylation and five O-glycosylation sites and their biological implications

Degradation of MEPE, DMP1, and release of SIBLING ASARM-peptides (minhibins): ASARM-peptide(s) are directly responsible for defective mineralization in HYP

Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics

Structure of human neutral endopeptidase (Neprilysin) complexed with phosphoramidon

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688-99

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scholarly article

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4054835

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10.1002/JBMR.1766

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3

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28

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2013-03-01T00:00:00Z

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230880358

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22991293

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