Secretion of sphingolipid hydrolase activator precursor, prosaposin
about
GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposinBinding and transport of gangliosides by prosaposinThe role of saposin C in Gaucher diseaseThe protective role of prosaposin and its receptors in the nervous systemNeurotrophic signalling pathway triggered by prosaposin in PC12 cells occurs through lipid raftsPurified recombinant human prosaposin forms oligomers that bind procathepsin D and affect its autoactivation.The exon 8-containing prosaposin gene splice variant is dispensable for mouse development, lysosomal function, and secretion.Cellular uptake of saposin (SAP) precursor and lysosomal delivery by the low density lipoprotein receptor-related protein (LRP).Sphingolipid activator proteins: proteins with complex functions in lipid degradation and skin biogenesis.Biosynthesis and degradation of mammalian glycosphingolipids.Temporal changes in prosaposin expression in the rat dentate gyrus after birth.Prosaposin overexpression following kainic acid-induced neurotoxicity.A prosaposin-derived Peptide alleviates kainic Acid-induced brain injury.Identification of prosaposin as a neurotrophic factor.Regional expression of prosaposin in the wild-type and saposin D-deficient mouse brain detected by an anti-mouse prosaposin-specific antibody.A saposin deficiency model in Drosophila: Lysosomal storage, progressive neurodegeneration and sensory physiological declineRole of sialic acid in the endocytosis of prosaposin by the nonciliated cells of the rat efferent ducts.Two Faces of Cathepsin D: Physiological Guardian Angel and Pathological Demon.Biosynthesis, processing, and targeting of sphingolipid activator protein (SAP )precursor in cultured human fibroblasts. Mannose 6-phosphate receptor-independent endocytosis of SAP precursor.An 18-mer Peptide Derived from Prosaposin Ameliorates the Effects of Aβ1-42 Neurotoxicity on Hippocampal Neurogenesis and Memory Deficit in Mice.Prosaposin is immunolocalized to muscle and prosaptides promote myoblast fusion and attenuate loss of muscle mass after nerve injury.Importance of splicing for prosaposin sortingProteolytic processing patterns of prosaposin in insect and mammalian cells.Additional biochemical findings in a patient and fetal sibling with a genetic defect in the sphingolipid activator protein (SAP) precursor, prosaposin. Evidence for a deficiency in SAP-1 and for a normal lysosomal neuraminidase.Decrease in prosaposin in the Dystrophic mdx mouse brain.TX14(A), a prosaposin-derived peptide, reverses established nerve disorders in streptozotocin-diabetic rats and prevents them in galactose-fed rats.Differential expression of the alternatively spliced forms of prosaposin mRNAs in rat choroid plexus.Quantitative Analysis of the Proteome Response to the Histone Deacetylase Inhibitor (HDACi) Vorinostat in Niemann-Pick Type C1 disease.Structural analysis of the mouse prosaposin (SGP-1) gene reveals the presence of an exon that is alternatively spliced in transcribed mRNAs.An 18-mer peptide fragment of prosaposin ameliorates place navigation disability, cortical infarction, and retrograde thalamic degeneration in rats with focal cerebral ischemia.Clinical, biochemical and molecular characterization of prosaposin deficiency.
P2860
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P2860
Secretion of sphingolipid hydrolase activator precursor, prosaposin
description
1991 nî lūn-bûn
@nan
1991 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Secretion of sphingolipid hydrolase activator precursor, prosaposin
@ast
Secretion of sphingolipid hydrolase activator precursor, prosaposin
@en
Secretion of sphingolipid hydrolase activator precursor, prosaposin
@nl
type
label
Secretion of sphingolipid hydrolase activator precursor, prosaposin
@ast
Secretion of sphingolipid hydrolase activator precursor, prosaposin
@en
Secretion of sphingolipid hydrolase activator precursor, prosaposin
@nl
prefLabel
Secretion of sphingolipid hydrolase activator precursor, prosaposin
@ast
Secretion of sphingolipid hydrolase activator precursor, prosaposin
@en
Secretion of sphingolipid hydrolase activator precursor, prosaposin
@nl
P2093
P1476
Secretion of sphingolipid hydrolase activator precursor, prosaposin
@en
P2093
P304
P356
10.1016/S0006-291X(05)80236-0
P407
P577
1991-04-30T00:00:00Z