Frabin, a novel FGD1-related actin filament-binding protein capable of changing cell shape and activating c-Jun N-terminal kinase
about
Endofin, an endosomal FYVE domain proteinEndofin recruits TOM1 to endosomesThe Phox homology (PX) domain, a new player in phosphoinositide signallingIdentification of a novel sequence in PDZ-RhoGEF that mediates interaction with the actin cytoskeletonFGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane rufflesPeripheral nerve demyelination caused by a mutant Rho GTPase guanine nucleotide exchange factor, frabin/FGD4Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4HCharcot-Marie-Tooth disease and intracellular trafficCdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.Cooperation of Cdc42 small G protein-activating and actin filament-binding activities of frabin in microspike formationPhosphatidylinositol 3-kinase and frabin mediate Cryptosporidium parvum cellular invasion via activation of Cdc42Nexilin: a novel actin filament-binding protein localized at cell-matrix adherens junctionInvolvement of Cdc42 and Rac small G proteins in invadopodia formation of RPMI7951 cells.Src kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin A receptor to JNK.Epstein-Barr virus-encoded LMP1 interacts with FGD4 to activate Cdc42 and thereby promote migration of nasopharyngeal carcinoma cells.Identification of a novel actin-binding domain within the Rho guanine nucleotide exchange factor TEM4.Signal transduction: stuck with FYVE domains.The phosphatidylinositol 3-phosphate-binding FYVE finger.Identification of a negative regulatory region for the exchange activity and characterization of T332I mutant of Rho guanine nucleotide exchange factor 10 (ARHGEF10).Silencing of Taxol-Sensitizer Genes in Cancer Cells: Lack of Sensitization Effects.Phosphatidylinositol 3-phosphate recognition and membrane docking by the FYVE domain.Frabin and other related Cdc42-specific guanine nucleotide exchange factors couple the actin cytoskeleton with the plasma membranePLEKHG3 enhances polarized cell migration by activating actin filaments at the cell frontMinireview: Role of genetic changes of faciogenital dysplasia protein 1 in human disease.A novel mutation in FGD4/FRABIN causes Charcot Marie Tooth disease type 4H in patients from a consanguineous Tunisian family.Structural basis for endosomal targeting by FYVE domains.Cdc42 and Rac small G proteins activated by trans-interactions of nectins are involved in activation of c-Jun N-terminal kinase, but not in association of nectins and cadherin to form adherens junctions, in fibroblasts.Association of frabin with specific actin and membrane structures.Two actions of frabin: direct activation of Cdc42 and indirect activation of Rac.A Mechanistic Understanding of Axon Degeneration in Chemotherapy-Induced Peripheral Neuropathy.Coordination of cytokinesis and cell separation by endosomal targeting of a Cdc42-specific guanine nucleotide exchange factor in Ustilago maydis.The amino acid motif L/IIxxFE defines a novel actin-binding sequence in PDZ-RhoGEF.Importance of spatial activation of Cdc42 and rac small G proteins by frabin for microspike formation in MDCK cells.A putative GDP-GTP exchange factor is required for development of the excretory cell in Caenorhabditis elegans.Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG.Regulation of cell separation in the dimorphic fungus Ustilago maydis.Two novel missense mutations in FGD4/FRABIN cause Charcot-Marie-Tooth type 4H (CMT4H).Association of Frabin with the Actin Cytoskeleton Is Essential for Microspike Formation through Activation of Cdc42 Small G Protein
P2860
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P2860
Frabin, a novel FGD1-related actin filament-binding protein capable of changing cell shape and activating c-Jun N-terminal kinase
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Frabin, a novel FGD1-related a ...... vating c-Jun N-terminal kinase
@ast
Frabin, a novel FGD1-related a ...... vating c-Jun N-terminal kinase
@en
Frabin, a novel FGD1-related a ...... vating c-Jun N-terminal kinase
@nl
type
label
Frabin, a novel FGD1-related a ...... vating c-Jun N-terminal kinase
@ast
Frabin, a novel FGD1-related a ...... vating c-Jun N-terminal kinase
@en
Frabin, a novel FGD1-related a ...... vating c-Jun N-terminal kinase
@nl
prefLabel
Frabin, a novel FGD1-related a ...... vating c-Jun N-terminal kinase
@ast
Frabin, a novel FGD1-related a ...... vating c-Jun N-terminal kinase
@en
Frabin, a novel FGD1-related a ...... vating c-Jun N-terminal kinase
@nl
P2093
P2860
P356
P1476
Frabin, a novel FGD1-related a ...... vating c-Jun N-terminal kinase
@en
P2093
H Nishioka
K Takahashi
K Takaishi
M Miyahara
P2860
P304
18697-18700
P356
10.1074/JBC.273.30.18697
P407
P577
1998-07-01T00:00:00Z