Increased secretion, altered processing, and glycosylation of pro-cathepsin D in human mammary cancer cells
about
Overexpression of human alpha-galactosidase A results in its intracellular aggregation, crystallization in lysosomes, and selective secretionCathepsin D--many functions of one aspartic proteaseAGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and DA human milk factor susceptible to cathepsin D inhibitors enhances human immunodeficiency virus type 1 infectivity and allows virus entry into a mammary epithelial cell line.Cathepsin-D, a key protease in breast cancer, is up-regulated in obese mouse and human adipose tissue, and controls adipogenesisInsulin-like growth factors I and II receptors in the breast cancer survival disparity among African-American women.Pro-cathepsin D interacts with the extracellular domain of the beta chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.Cathepsin D: Regulation in mammary gland remodeling, misregulation in breast cancerDeficiency in trefoil factor 1 (TFF1) increases tumorigenicity of human breast cancer cells and mammary tumor development in TFF1-knockout mice.Reevaluating cathepsin D as a biomarker for breast cancer: serum activity levels versus histopathology.Correlation between cathepsin D expression and p53 protein nuclear accumulation in oesophageal squamous cell carcinoma.Cathepsin D in invasive ductal NOS breast carcinoma as defined by immunohistochemistry. No correlation with survival at 5 years.Relationship between cathepsin D, urokinase, and plasminogen activator inhibitors in malignant vs benign breast tumours.Bile acids influence the growth, oestrogen receptor and oestrogen-regulated proteins of MCF-7 human breast cancer cells.Immunohistochemical and other features of breast carcinomas presenting clinically compared with those detected by cancer screeningProteolytic-antiproteolytic balance and its regulation in carcinogenesis.Proteolytic Systems in Milk: Perspectives on the Evolutionary Function within the Mammary Gland and the Infant.Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cellsLow levels of cathepsin D are associated with a poor prognosis in endometrial cancer.Cathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis.Regulation of protein glycosylation and sorting by the Golgi matrix proteins GRASP55/65.Prolactin promotes the secretion of active cathepsin D at the basal side of rat mammary acini.Effect of carbohydrate position on lysosomal transport of procathepsin L.Identification of differentially secreted biomarkers using LC-MS/MS in isogenic cell lines representing a progression of breast cancer.Differential protein expression in perfusates from metastasized rat livers.Pre-operative urinary cathepsin D is associated with survival in patients with renal cell carcinoma.Procathepsin D and cancer: From molecular biology to clinical applications.Two Faces of Cathepsin D: Physiological Guardian Angel and Pathological Demon.Elucidating the function of secreted maspin: inhibiting cathepsin D-mediated matrix degradation.Detection of oral squamous cell carcinoma metastasis with cathepsin D: An immunohistochemical approach.Exploration of subsite binding specificity of human cathepsin D through kinetics and rule-based molecular modeling.Cation-dependent mannose-6-phosphate receptor expression and distribution are influenced by estradiol in MCF-7 breast cancer cells
P2860
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P2860
Increased secretion, altered processing, and glycosylation of pro-cathepsin D in human mammary cancer cells
description
1989 nî lūn-bûn
@nan
1989 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Increased secretion, altered p ...... in human mammary cancer cells
@ast
Increased secretion, altered p ...... in human mammary cancer cells
@en
Increased secretion, altered p ...... in human mammary cancer cells
@nl
type
label
Increased secretion, altered p ...... in human mammary cancer cells
@ast
Increased secretion, altered p ...... in human mammary cancer cells
@en
Increased secretion, altered p ...... in human mammary cancer cells
@nl
prefLabel
Increased secretion, altered p ...... in human mammary cancer cells
@ast
Increased secretion, altered p ...... in human mammary cancer cells
@en
Increased secretion, altered p ...... in human mammary cancer cells
@nl
P2093
P1433
P1476
Increased secretion, altered p ...... in human mammary cancer cells
@en
P2093
H Rochefort
P Montcourrier
V Cavailles
P304
P407
P577
1989-07-15T00:00:00Z