Use of the thiol-specific derivatizing agent N-iodoacetyl-3-[125I]iodotyrosine to demonstrate conformational differences between the unbound and hsp90-bound glucocorticoid receptor hormone binding domain
about
The Hsp organizer protein hop enhances the rate of but is not essential for glucocorticoid receptor folding by the multiprotein Hsp90-based chaperone systemNucleotide binding states of hsp70 and hsp90 during sequential steps in the process of glucocorticoid receptor.hsp90 heterocomplex assemblyMutations at positions 547-553 of rat glucocorticoid receptors reveal that hsp90 binding requires the presence, but not defined composition, of a seven-amino acid sequence at the amino terminus of the ligand binding domain11beta-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of type 2 diabetes.Folding of the glucocorticoid receptor by the reconstituted Hsp90-based chaperone machinery. The initial hsp90.p60.hsp70-dependent step is sufficient for creating the steroid binding conformation.Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70.Ubiquitylation of nuclear receptors: new linkages and therapeutic implications.Solubility-promoting function of Hsp90 contributes to client maturation and robust cell growth.Hsp90 and client protein maturation.hsp90 is required for heme binding and activation of apo-neuronal nitric-oxide synthase: geldanamycin-mediated oxidant generation is unrelated to any action of hsp90.Stoichiometry, abundance, and functional significance of the hsp90/hsp70-based multiprotein chaperone machinery in reticulocyte lysate.Biomolecular interaction analysis of IFN gamma-induced signaling events in whole-cell lysates: prevalence of latent STAT1 in high-molecular weight complexes.Binding of hsp90 to the glucocorticoid receptor requires a specific 7-amino acid sequence at the amino terminus of the hormone-binding domain.Stepwise assembly of a glucocorticoid receptor.hsp90 heterocomplex resolves two sequential ATP-dependent events involving first hsp70 and then hsp90 in opening of the steroid binding pocket.Effect of 4-hydroxynonenal on antioxidant capacity and apoptosis induction in Jurkat T cells.
P2860
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P2860
Use of the thiol-specific derivatizing agent N-iodoacetyl-3-[125I]iodotyrosine to demonstrate conformational differences between the unbound and hsp90-bound glucocorticoid receptor hormone binding domain
description
1996 nî lūn-bûn
@nan
1996 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Use of the thiol-specific deri ...... eceptor hormone binding domain
@ast
Use of the thiol-specific deri ...... eceptor hormone binding domain
@en
Use of the thiol-specific deri ...... eceptor hormone binding domain
@nl
type
label
Use of the thiol-specific deri ...... eceptor hormone binding domain
@ast
Use of the thiol-specific deri ...... eceptor hormone binding domain
@en
Use of the thiol-specific deri ...... eceptor hormone binding domain
@nl
prefLabel
Use of the thiol-specific deri ...... eceptor hormone binding domain
@ast
Use of the thiol-specific deri ...... eceptor hormone binding domain
@en
Use of the thiol-specific deri ...... eceptor hormone binding domain
@nl
P2093
P2860
P356
P1476
Use of the thiol-specific deri ...... eceptor hormone binding domain
@en
P2093
A M Silverstein
L F Stancato
P2860
P304
P356
10.1074/JBC.271.15.8831
P407
P577
1996-04-12T00:00:00Z