about
Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switchingAsymmetric distribution of histones during Drosophila male germline stem cell asymmetric divisionsRelated Mechanisms of Antibody Somatic Hypermutation and Class Switch RecombinationCytokine reporter mice: the special case of IL-10B cell receptor editing in tolerance and autoimmunityAllelome.PRO, a pipeline to define allele-specific genomic features from high-throughput sequencing data.Immunoglobulin heavy chain exclusion in the sharkIndependent recruitment of Igh alleles in V(D)J recombination.Analysis of mice lacking DNaseI hypersensitive sites at the 5' end of the IgH locusClonally stable Vκ allelic choice instructs Igκ repertoire.TCR beta feedback signals inhibit the coupling of recombinationally accessible V beta 14 segments with DJ beta complexesPosttranscriptional silencing of VbetaDJbetaCbeta genes contributes to TCRbeta allelic exclusion in mammalian lymphocytes.The pre-B cell receptor checkpoint.The ataxia telangiectasia mutated and cyclin D3 proteins cooperate to help enforce TCRβ and IgH allelic exclusionEpigenetic regulation of antigen receptor gene rearrangementA major deletion in the Vκ-Jκ intervening region results in hyperelevated transcription of proximal Vκ genes and a severely restricted repertoire.Antigen receptor allelic exclusion: an update and reappraisalElements between the IgH variable (V) and diversity (D) clusters influence antisense transcription and lineage-specific V(D)J recombination.Cis-regulatory elements and epigenetic changes control genomic rearrangements of the IgH locus.CTCF-binding elements 1 and 2 in the Igh intergenic control region cooperatively regulate V(D)J recombination.Regulation of TCRβ allelic exclusion by gene segment proximity and accessibilityIgG1+ ovalbumin-specific B-cell transnuclear mice show class switch recombination in rare allelically included B cellsIgkappa allelic inclusion is a consequence of receptor editing.Fluorescence tagging and inducible depletion of PD-L2-expressing B-1 B cells in vivoTurning T-cell receptor beta recombination on and off: more questions than answers.A plasma cell differentiation quality control ablates B cell clones with biallelic Ig rearrangements and truncated Ig productionFrom gene amplification to V(D)J recombination and back: a personal account of my early years in B cell biologyA role for the IgH intronic enhancer E mu in enforcing allelic exclusion.Biallelic, ubiquitous transcription from the distal germline Ig{kappa} locus promoter during B cell development.Highly sensitive and unbiased approach for elucidating antibody repertoires.Equal transcription rates of productively and nonproductively rearranged immunoglobulin mu heavy chain alleles in a pro-B cell line.'Runxs and regulations' of sensory and motor neuron subtype differentiation: implications for hematopoietic development.Vbeta cluster sequences reduce the frequency of primary Vbeta2 and Vbeta14 rearrangements.Hematopoietic stem cells for cancer immunotherapyIntrinsic transcriptional heterogeneity in B cells controls early class switching to IgE.Epigenetic aspects of lymphocyte antigen receptor gene rearrangement or 'when stochasticity completes randomness'.Mechanisms of programmed DNA lesions and genomic instability in the immune system.Mechanisms of pre-B-cell receptor checkpoint control and its oncogenic subversion in acute lymphoblastic leukemia.Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody GenesLocus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The lingering enigma of the allelic exclusion mechanism
@ast
The lingering enigma of the allelic exclusion mechanism
@en
The lingering enigma of the allelic exclusion mechanism
@nl
type
label
The lingering enigma of the allelic exclusion mechanism
@ast
The lingering enigma of the allelic exclusion mechanism
@en
The lingering enigma of the allelic exclusion mechanism
@nl
prefLabel
The lingering enigma of the allelic exclusion mechanism
@ast
The lingering enigma of the allelic exclusion mechanism
@en
The lingering enigma of the allelic exclusion mechanism
@nl
P1433
P1476
The lingering enigma of the allelic exclusion mechanism
@en
P2093
Frederick W Alt
Raul Mostoslavsky
P304
P356
10.1016/J.CELL.2004.08.023
P407
P577
2004-09-03T00:00:00Z