Signal transducer and activator of transcription 5A/B in prostate and breast cancers - Test2 - elhamkhani - TriplyDB

Signal transducer and activator of transcription 5A/B in prostate and breast cancers

Signal transducer and activator of transcription 5A/B in prostate and breast cancers

http://www.wikidata.org/entity/Q28281791

about

Low levels of Stat5a protein in breast cancer are associated with tumor progression and unfavorable clinical outcomes The tumor suppressor hTid1 inhibits STAT5b activity via functional interaction PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers Suppressor of cytokine signaling (SOCS)-1 is expressed in human prostate cancer and exerts growth-inhibitory function through down-regulation of cyclins and cyclin-dependent kinases Inhibition of STAT5a by Naa10p contributes to decreased breast cancer metastasis STAT6 expression in glioblastoma promotes invasive growth Mucin 13: structure, function, and potential roles in cancer pathogenesis.Expression of STAT5, COX-2 and PIAS3 in correlation with NSCLC histhopathological features.Dystroglycan controls signaling of multiple hormones through modulation of STAT5 activity.Progress towards the development of SH2 domain inhibitors.Transcription factor Stat5a/b as a therapeutic target protein for prostate cancer.Signal transducer and activator of transcription 5a/b: biomarker and therapeutic target in prostate and breast cancer Negative cross talk between NFAT1 and Stat5 signaling in breast cancer.STAT5A-mediated SOCS2 expression regulates Jak2 and STAT3 activity following c-Src inhibition in head and neck squamous carcinoma Signal transducer and activator of transcription 5 as a key signaling pathway in normal mammary gland developmental biology and breast cancer.CSF2 Overexpression Is Associated with STAT5 Phosphorylation and Poor Prognosis in Patients with Urothelial Carcinoma.Coffee polyphenols change the expression of STAT5B and ATF-2 modifying cyclin D1 levels in cancer cells DARPP32, STAT5 and STAT3 mRNA expression ratios in glioblastomas are associated with patient outcome.β-arrestin-selective G protein-coupled receptor agonists engender unique biological efficacy in vivo Dynamic trafficking of STAT5 depends on an unconventional nuclear localization signal Life stage differences in mammary gland gene expression profile in non-human primates.Prognostic significance of signal transducer and activator of transcription 5 and 5b expression in Epstein-Barr virus-positive patients with chronic lymphocytic leukemia SOCS2 correlates with malignancy and exerts growth-promoting effects in prostate cancer.An N-terminal splice variant of human Stat5a that interacts with different transcription factors is the dominant form expressed in invasive ductal carcinoma.Androgen receptor-dependent and -independent mechanisms driving prostate cancer progression: Opportunities for therapeutic targeting from multiple angles.Targeting transcription factor Stat5a/b as a therapeutic strategy for prostate cancer.What we have learnt about PIKE from the knockout mice.Robust gene network analysis reveals alteration of the STAT5a network as a hallmark of prostate cancer.Retinoic acid amide inhibits JAK/STAT pathway in lung cancer which leads to apoptosis.Reactive stroma component COL6A1 is upregulated in castration-resistant prostate cancer and promotes tumor growth.N-terminal truncation of Stat5a/b circumvents PIAS3-mediated transcriptional inhibition of Stat5 in prostate cancer cells.Identification of Gene and MicroRNA Signatures for Oral Cancer Developed from Oral Leukoplakia.Nanomolar-Potency Small Molecule Inhibitor of STAT5 Protein.Gender-specific transcriptomic response to environmental exposure in Flemish adults.The prevalence and associated factors of colorectal neoplasms in acromegaly: a single center based study.High incidence of mammary intraepithelial neoplasia development in Men1-disrupted murine mammary glands.Mammalian target of rapamycin complex 2 regulates muscle glucose uptake during exercise in mice.Effects of Pimozide Derivatives on pSTAT5 in K562 Cells.

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Signal transducer and activator of transcription 5A/B in prostate and breast cancers

http://www.wikidata.org/entity/Q28281791

description

2008 nî lūn-bûn

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2008 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2008 թվականի հունիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Signal transducer and activator of transcription 5A/B in prostate and breast cancers

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Signal transducer and activator of transcription 5A/B in prostate and breast cancers

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Signal transducer and activator of transcription 5A/B in prostate and breast cancers

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type

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Signal transducer and activator of transcription 5A/B in prostate and breast cancers

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Signal transducer and activator of transcription 5A/B in prostate and breast cancers

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Signal transducer and activator of transcription 5A/B in prostate and breast cancers

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Signal transducer and activator of transcription 5A/B in prostate and breast cancers

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Signal transducer and activator of transcription 5A/B in prostate and breast cancers

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Signal transducer and activator of transcription 5A/B in prostate and breast cancers

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Endocrine-related cancer

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Signal transducer and activator of transcription 5A/B in prostate and breast cancers

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Marja T Nevalainen

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Shyh-Han Tan

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P2860

Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling

cDNA cloning, expression and chromosome mapping of the human STAT4 gene: both STAT4 and STAT1 genes are mapped to 2q32.2-->q32.3

Inhibition of Stat1-mediated gene activation by PIAS1

hZimp7, a novel PIAS-like protein, enhances androgen receptor-mediated transcription and interacts with SWI/SNF-like BAF complexes

Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells

Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade.

Identification and purification of human Stat proteins activated in response to interleukin-2

Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse

Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA

Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1.

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10.1677/ERC-08-0013

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