Control of daughter cell fates during asymmetric division: interaction of Numb and Notch
about
Notch signaling induces rapid degradation of achaete-scute homolog 1.The adaptor-associated kinase 1, AAK1, is a positive regulator of the Notch pathwayIdentification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with NumbIdentification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor proteinaPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb.The Mdm2 oncoprotein interacts with the cell fate regulator NumbLNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradationThe neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNASiah-1 binds and regulates the function of NumbThe TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitorsLinking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localizationNumb links extracellular cues to intracellular polarity machinery to promote chemotaxisLoss of negative regulation by Numb over Notch is relevant to human breast carcinogenesisDistinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineageNumb is an endocytic proteinSpindle orientation in mammalian cerebral cortical developmentNotch activity in neural progenitors coordinates cytokinesis and asymmetric differentiationNon-canonical Notch signaling: emerging role and mechanismGain of function notch phenotypes associated with ectopic expression of the Su(H) C-terminal domain illustrate separability of Notch and hairless-mediated activitiesThe Numb/p53 circuitry couples replicative self-renewal and tumor suppression in mammary epithelial cells.Notch and Prospero repress proliferation following cyclin E overexpression in the Drosophila bristle lineageZebrafish numb and numblike are involved in primitive erythrocyte differentiationS-phase favours notch cell responsiveness in the Drosophila bristle lineageMultiple modes of peptide recognition by the PTB domain of the cell fate determinant NumbStructure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificityAssociation of transcription factor YY1 with the high molecular weight Notch complex suppresses the transactivation activity of NotchAsymmetric cell divisionLnx2 ubiquitin ligase is essential for exocrine cell differentiation in the early zebrafish pancreasThe mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domain-containing numb binding protein, LNXA role for the primary cilium in Notch signaling and epidermal differentiation during skin developmentNotch1 signaling stimulates proliferation of immature cardiomyocytesPhosphorylation of Numb regulates its interaction with the clathrin-associated adaptor AP-2Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout miceEya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epitheliumTargeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborizationNodal points and complexity of Notch-Ras signal integrationAdapting for endocytosis: roles for endocytic sorting adaptors in directing neural development.Notch inhibition as a promising new approach to cancer therapy.Mitotic spindle rotation and mode of cell division in the developing telencephalon
P2860
Q24293622-5938057E-524E-4ACA-B4AD-0416FBACDBBDQ24298942-9F21079C-246C-4770-A74C-4D02038ACC5EQ24305261-E2E8FBBF-BCEB-49F0-8609-652094CFDFD2Q24309682-08243A24-85B9-4F97-A37A-7640536A5845Q24315811-572E2407-3EE2-45AF-9FBA-CB396F01ADD0Q24338740-27C546E9-2D9C-484C-96E9-CDF471105617Q24522545-EB9E1E03-802E-4BEE-842E-EC661184E376Q24536102-D0C38F31-F929-46C0-B408-06DC36AF41F8Q24550956-93CE91A8-55F7-4873-931C-59D58A8D3E50Q24555052-5A83961C-5294-48A0-A590-79EA96907C14Q24569665-2C826341-DEDE-42CF-A2F0-08A680E0042BQ24595932-25CB0600-CEFC-4AB1-9F5D-DE29E47B4762Q24630294-0B846A3F-11B9-4F3F-9A52-CC45CCCFB276Q24676117-8D4CA592-2E5E-4765-B3AF-69907913B809Q24678598-5E89E2C6-2D5A-4779-9386-C16730C237A8Q24681102-4DA5815F-B617-49A5-B79A-F000EA5CEFF7Q26829174-105F217C-9DC6-4C18-9C4B-E75E9EA83900Q26830299-10F7090C-BEC1-4ED5-8AA7-1208DA41B7D2Q26863550-A2F153B3-2D84-4DD8-99AF-2D7A095671C2Q27301042-6EB071EA-60F9-4CA5-B990-D7700424563DQ27309278-5914C94B-C0BF-4A9A-8550-62BCFBBD10A8Q27312082-3218A5B8-A5AB-45EA-BC73-3C8DB3CCCD9CQ27315869-C5FBC937-AFAA-4D14-86DD-03168E7257C2Q27438149-0740FEBA-3A53-4B79-B65E-2E04676610F9Q27622039-406DFCC9-7EB3-4FA8-BAB0-53309AF7ADD9Q27766331-CFA4DC37-B48C-4E81-BE4D-E4F21D945962Q28200963-8FA56045-E5C2-45E0-A12C-94DEA4454968Q28269713-AB07C175-3F64-4C7C-B59B-F906DF890D44Q28312136-949F292F-E095-4CB2-A767-9468A328CFC9Q28509667-6D230B2B-3AF0-427B-A0F7-0D0F21889D4AQ28510710-E9AA1AB1-0E63-4696-9691-2D94FB445B53Q28565088-41E27899-9E7A-44D8-81C4-42759403C38EQ28571594-40EAC2F2-97BD-4826-8AF4-B3D528CFB489Q28586326-9108EB98-446C-49F9-9D62-056C551B95ADQ28593989-98A6C2A2-B682-4031-B962-97E184DD09EBQ28594301-9B3C2184-48EF-4605-9926-F41C39BAB439Q28755679-B7A9EE1D-6385-43E9-8DB6-48E3EC7B4E9EQ30300136-AF98E32E-30E2-4604-941A-A30E9812FF7DQ30426785-A6A74C16-A2C6-4A92-98C2-11E2F3A3C66EQ30477646-AE549671-42FF-4B26-B2D0-D43438A2EFB6
P2860
Control of daughter cell fates during asymmetric division: interaction of Numb and Notch
description
1996 nî lūn-bûn
@nan
1996 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Control of daughter cell fates during asymmetric division: interaction of Numb and Notch
@ast
Control of daughter cell fates during asymmetric division: interaction of Numb and Notch
@en
Control of daughter cell fates during asymmetric division: interaction of Numb and Notch
@nl
type
label
Control of daughter cell fates during asymmetric division: interaction of Numb and Notch
@ast
Control of daughter cell fates during asymmetric division: interaction of Numb and Notch
@en
Control of daughter cell fates during asymmetric division: interaction of Numb and Notch
@nl
prefLabel
Control of daughter cell fates during asymmetric division: interaction of Numb and Notch
@ast
Control of daughter cell fates during asymmetric division: interaction of Numb and Notch
@en
Control of daughter cell fates during asymmetric division: interaction of Numb and Notch
@nl
P2093
P3181
P1433
P1476
Control of daughter cell fates during asymmetric division: interaction of Numb and Notch
@en
P2093
P3181
P356
10.1016/S0896-6273(00)80278-0
P407
P577
1996-07-01T00:00:00Z