Lin28: primal regulator of growth and metabolism in stem cells - Test2 - elhamkhani - TriplyDB

Lin28: primal regulator of growth and metabolism in stem cells

Lin28: primal regulator of growth and metabolism in stem cells

http://www.wikidata.org/entity/Q28288454

about

Lin28 and let-7 in cell metabolism and cancer RNA-Binding Proteins in the Regulation of miRNA Activity: A Focus on Neuronal Functions Functional Integration of mRNA Translational Control Programs Insights into the post-transcriptional regulation of the mitochondrial electron transport chain Injuries to appendage extremities and digit tips: A clinical and cellular update Lin28 enhances tissue repair by reprogramming cellular metabolism Lin28 sustains early renal progenitors and induces Wilms tumor Transcriptomic characterization of C57BL/6 mouse embryonic stem cell differentiation and its modulation by developmental toxicants The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea.A Lin28 homologue reprograms differentiated cells to stem cells in the moss Physcomitrella patens Reprogramming of the chick retinal pigmented epithelium after retinal injury Oncogenic mechanisms of Lin28 in breast cancer: new functions and therapeutic opportunities.Identification of hair shaft progenitors that create a niche for hair pigmentation.RNA-binding proteins in human oogenesis: Balancing differentiation and self-renewal in the female fetal germline The bromodomain inhibitor JQ1 triggers growth arrest and apoptosis in testicular germ cell tumours in vitro and in vivo.Metabolic requirements for the maintenance of self-renewing stem cells.Inhibition of Let-7 microRNA attenuates myocardial remodeling and improves cardiac function postinfarction in mice.MicroRNA-188 suppresses G1/S transition by targeting multiple cyclin/CDK complexes Coordination of insulin and Notch pathway activities by microRNA miR-305 mediates adaptive homeostasis in the intestinal stem cells of the Drosophila gut.Wnt/β-catenin and FGF signalling direct the specification and maintenance of a neuromesodermal axial progenitor in ensembles of mouse embryonic stem cells Genetic insulin resistance is a potent regulator of gene expression and proliferation in human iPS cells Müller glial cell reprogramming and retina regeneration.SET7/9 methylation of the pluripotency factor LIN28A is a nucleolar localization mechanism that blocks let-7 biogenesis in human ESCs Engineering Hematopoietic Stem Cells: Lessons from Development.Short loop-targeting oligoribonucleotides antagonize Lin28 and enable pre-let-7 processing and suppression of cell growth in let-7-deficient cancer cells.TRAF2 recruitment via T61 in CD30 drives NFκB activation and enhances hESC survival and proliferation.MUC1-C Induces the LIN28B→LET-7→HMGA2 Axis to Regulate Self-Renewal in NSCLC Regulation of pluripotency by RNA binding proteins Concise review: custodians of the transcriptome: how microRNAs guard stemness in squamous epithelia.Novel insights into embryonic stem cell self-renewal revealed through comparative human and mouse systems biology networks Lin28 promotes the proliferative capacity of neural progenitor cells in brain development.LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans.The ribonuclease DIS3 promotes let-7 miRNA maturation by degrading the pluripotency factor LIN28B mRNA.Lhx8 regulates primordial follicle activation and postnatal folliculogenesis.The role of Lin28b in myeloid and mast cell differentiation and mast cell malignancy Stress granules, P-bodies and cancer.Aberrant regulation of the LIN28A/LIN28B and let-7 loop in human malignant tumors and its effects on the hallmarks of cancer LIN28A Modulates Splicing and Gene Expression Programs in Breast Cancer Cells.Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor.A Single Let-7 MicroRNA Bypasses LIN28-Mediated Repression.

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P2860

Lin28: primal regulator of growth and metabolism in stem cells

http://www.wikidata.org/entity/Q28288454

description

2013 nî lūn-bûn

@nan

2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2013 թվականի ապրիլին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

@zh-mo

2013年論文

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2013年论文

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name

Lin28: primal regulator of growth and metabolism in stem cells

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Lin28: primal regulator of growth and metabolism in stem cells

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Lin28: primal regulator of growth and metabolism in stem cells

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type

label

Lin28: primal regulator of growth and metabolism in stem cells

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Lin28: primal regulator of growth and metabolism in stem cells

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Lin28: primal regulator of growth and metabolism in stem cells

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Lin28: primal regulator of growth and metabolism in stem cells

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Lin28: primal regulator of growth and metabolism in stem cells

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Lin28: primal regulator of growth and metabolism in stem cells

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J.STEM.2013.03.005

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P1476

Lin28: primal regulator of growth and metabolism in stem cells

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P2860

MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output

Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation

Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules

LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans

Understanding the Warburg effect: the metabolic requirements of cell proliferation

Selective blockade of microRNA processing by Lin28

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395-406

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scholarly article

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10.1016/J.STEM.2013.03.005

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4

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George Q. Daley

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