Evidence for a dipyrromethane cofactor at the catalytic site of E. coli porphobilinogen deaminase
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Studies on the mechanism of hydroxymethylbilane synthase concerning the role of arginine residues in substrate bindingStructure of human porphobilinogen deaminase at 2.8 A: the molecular basis of acute intermittent porphyriaStructural evidence for the partially oxidized dipyrromethene and dipyrromethanone forms of the cofactor of porphobilinogen deaminase: structures of theBacillus megateriumenzyme at near-atomic resolutionInsights into the mechanism of pyrrole polymerization catalysed by porphobilinogen deaminase: high-resolution X-ray studies of the Arabidopsis thaliana enzymeUnique properties of Plasmodium falciparum porphobilinogen deaminaseIdentification of Shell Colour Pigments in Marine Snails Clanculus pharaonius and C. margaritarius (Trochoidea; Gastropoda)Time-resolved and static-ensemble structural chemistry of hydroxymethylbilane synthaseReflections on the discovery of nature's pathways to vitamin B12.Tetrapyrrole Metabolism in Arabidopsis thaliana.Availability of porphobilinogen controls appearance of porphobilinogen deaminase activity in Escherichia coli K-12.Structure and function of enzymes in heme biosynthesis.Prokaryotic Heme Biosynthesis: Multiple Pathways to a Common Essential Product.Allosteric inhibition of human lymphoblast and purified porphobilinogen deaminase by protoporphyrinogen and coproporphyrinogen. A possible mechanism for the acute attack of variegate porphyria.The three-dimensional structures of mutants of porphobilinogen deaminase: toward an understanding of the structural basis of acute intermittent porphyria.Crystallization and preliminary X-ray characterization of the tetrapyrrole-biosynthetic enzyme porphobilinogen deaminase from Arabidopsis thaliana.Evidence that the pyrromethane cofactor of hydroxymethylbilane synthase (porphobilinogen deaminase) is bound to the protein through the sulphur atom of cysteine-242.Purification and properties of porphobilinogen deaminase from Arabidopsis thaliana.Evidence that the pyrromethane cofactor of hydroxymethylbilane synthase (porphobilinogen deaminase) is bound through the sulphur atom of a cysteine residue.Conformational stability and activity analysis of two hydroxymethylbilane synthase mutants, K132N and V215E, with different phenotypic association with acute intermittent porphyria.Purification, crystallization and properties of porphobilinogen deaminase from a recombinant strain of Escherichia coli K12The three-dimensional structure of Escherichia coli porphobilinogen deaminase at 1.76-A resolution.Mutagenesis of arginine residues in the catalytic cleft of Escherichia coli porphobilinogen deaminase that affects dipyrromethane cofactor assembly and tetrapyrrole chain initiation and elongation.Discovery that the assembly of the dipyrromethane cofactor of porphobilinogen deaminase holoenzyme proceeds initially by the reaction of preuroporphyrinogen with the apoenzyme.Crystallization and preliminary X-ray characterization of the tetrapyrrole-biosynthetic enzyme porphobilinogen deaminase from Bacillus megaterium.Functional characterization of the early steps of tetrapyrrole biosynthesis and modification in Desulfovibrio vulgaris Hildenborough.Identification and characterization of 40 novel hydroxymethylbilane synthase mutations that cause acute intermittent porphyria.Human hydroxymethylbilane synthase: Molecular dynamics of the pyrrole chain elongation identifies step-specific residues that cause AIP.Identification of a cysteine residue as the binding site for the dipyrromethane cofactor at the active site of Escherichia coli porphobilinogen deaminase.Structural basis of pyrrole polymerization in human porphobilinogen deaminase
P2860
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P2860
Evidence for a dipyrromethane cofactor at the catalytic site of E. coli porphobilinogen deaminase
description
1987 nî lūn-bûn
@nan
1987 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
name
Evidence for a dipyrromethane ...... coli porphobilinogen deaminase
@ast
Evidence for a dipyrromethane ...... coli porphobilinogen deaminase
@en
Evidence for a dipyrromethane ...... coli porphobilinogen deaminase
@nl
type
label
Evidence for a dipyrromethane ...... coli porphobilinogen deaminase
@ast
Evidence for a dipyrromethane ...... coli porphobilinogen deaminase
@en
Evidence for a dipyrromethane ...... coli porphobilinogen deaminase
@nl
prefLabel
Evidence for a dipyrromethane ...... coli porphobilinogen deaminase
@ast
Evidence for a dipyrromethane ...... coli porphobilinogen deaminase
@en
Evidence for a dipyrromethane ...... coli porphobilinogen deaminase
@nl
P2860
P3181
P1433
P1476
Evidence for a dipyrromethane ...... coli porphobilinogen deaminase
@en
P2093
M J Warren
P M Jordan
P2860
P3181
P356
10.1016/0014-5793(87)81136-5
P407
P577
1987-12-10T00:00:00Z