Reversible phosphorylation of Bcl2 following interleukin 3 or bryostatin 1 is mediated by direct interaction with protein phosphatase 2A
about
The B56alpha regulatory subunit of protein phosphatase 2A is a target for regulation by double-stranded RNA-dependent protein kinase PKRPotentiation of GATA-2 activity through interactions with the promyelocytic leukemia protein (PML) and the t(15;17)-generated PML-retinoic acid receptor alpha oncoproteinIntegrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta.PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulumProtein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signallingProtein phosphatase 1alpha is a Ras-activated Bad phosphatase that regulates interleukin-2 deprivation-induced apoptosisAlterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the A beta subunit geneCharacterizing the novel protein p33MONOXProtein kinase C isoforms: Multi-functional regulators of cell life and deathToxicology of microcystins with reference to cases of human intoxications and epidemiological investigations of exposures to cyanobacteria and cyanotoxins.Spindle poisons and cell fate: a tale of two pathways.Actions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits.Role of Ku70 in deubiquitination of Mcl-1 and suppression of apoptosis.Use of marine toxins in combination with cytotoxic drugs for induction of apoptosis in acute myelogenous leukaemia cells.Differentiation therapy in poor risk myeloid malignancies: Results of a dose finding study of the combination bryostatin-1 and GM-CSF.Bcl2's flexible loop domain regulates p53 binding and survivalProtein phosphatase 2A catalytic subunit α (PP2Acα) maintains survival of committed erythroid cells in fetal liver erythropoiesis through the STAT5 pathway.Induction of apoptosis by adenovirus E4orf4 protein is specific to transformed cells and requires an interaction with protein phosphatase 2A.A Three Stage Integrative Pathway Search (TIPS) framework to identify toxicity relevant genes and pathways.Osteosarcoma Phenotype Is Inhibited by 3,4-Methylenedioxy-β-nitrostyreneApoptosis in cerebral ischemia: executional and regulatory signaling mechanisms.BCL2 family of apoptosis-related genes: functions and clinical implications in cancer.Protein phosphatase 2A inactivates Bcl2's antiapoptotic function by dephosphorylation and up-regulation of Bcl2-p53 binding.Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases.A nonhomologous end-joining pathway is required for protein phosphatase 2A promotion of DNA double-strand break repair.Molecular aspects of microcystin-induced hepatotoxicity and hepatocarcinogenesis.miR-3941: A novel microRNA that controls IGBP1 expression and is associated with malignant progression of lung adenocarcinoma.Regulation of anti-apoptotic BCL2-proteins by non-canonical interactions: the next step forward or two steps back?c-Myc and caspase-2 are involved in activating Bax during cytotoxic drug-induced apoptosis.Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway.Targeting PKC-mediated signal transduction pathways using enzastaurin to promote apoptosis in acute myeloid leukemia-derived cell lines and blast cellsB56-associated protein phosphatase 2A is required for survival and protects from apoptosis in Drosophila melanogaster.Protein phosphatase 4 regulates apoptosis in leukemic and primary human T-cells.Protein phosphatase 2A enhances the proapoptotic function of Bax through dephosphorylation.Dephosphorylation of Bcl-2 by protein phosphatase 2A results in apoptosis resistance.Bcl-2 phosphorylation is required for inhibition of oxidative stress-induced lysosomal leak and ensuing apoptosis.Radiation-induced apoptosis in human myeloma cell line increases BCL-2/BAX dimer formation and does not result in BAX/BAX homodimerization.Novel role for JNK as a stress-activated Bcl2 kinase.Adenovirus E4orf4 protein interacts with both Balpha and B' subunits of protein phosphatase 2A, but E4orf4-induced apoptosis is mediated only by the interaction with Balpha.A conditionally-active form of MEK1 results in autocrine tranformation of human and mouse hematopoietic cells.
P2860
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P2860
Reversible phosphorylation of Bcl2 following interleukin 3 or bryostatin 1 is mediated by direct interaction with protein phosphatase 2A
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
name
Reversible phosphorylation of ...... on with protein phosphatase 2A
@ast
Reversible phosphorylation of ...... on with protein phosphatase 2A
@en
Reversible phosphorylation of ...... on with protein phosphatase 2A
@nl
type
label
Reversible phosphorylation of ...... on with protein phosphatase 2A
@ast
Reversible phosphorylation of ...... on with protein phosphatase 2A
@en
Reversible phosphorylation of ...... on with protein phosphatase 2A
@nl
prefLabel
Reversible phosphorylation of ...... on with protein phosphatase 2A
@ast
Reversible phosphorylation of ...... on with protein phosphatase 2A
@en
Reversible phosphorylation of ...... on with protein phosphatase 2A
@nl
P2093
P2860
P356
P1476
Reversible phosphorylation of ...... on with protein phosphatase 2A
@en
P2093
P2860
P304
P356
10.1074/JBC.273.51.34157
P407
P577
1998-12-18T00:00:00Z