about
Effects of Animal Venoms and Toxins on Hallmarks of CancerDisintegrins from snake venoms and their applications in cancer research and therapy.Distinctive expansion of potential virulence genes in the genome of the oomycete fish pathogen Saprolegnia parasiticaDynamics and functional differences between dendroaspin and rhodostomin: Insights into protein scaffolds in integrin recognitionA review on the Scorpaena plumieri fish venom and its bioactive compoundsInhibition of lung tumor colonization and cell migration with the disintegrin crotatroxin 2 isolated from the venom of Crotalus atrox.Crotaline Fab antivenom reverses platelet dysfunction induced by Crotalus scutulatus venom: an in vitro study.CC-PLA2-1 and CC-PLA2-2, two Cerastes cerastes venom-derived phospholipases A2, inhibit angiogenesis both in vitro and in vivo.Effects of the RGD loop and C-terminus of rhodostomin on regulating integrin αIIbβ3 recognition.The mojastin mutant Moj-DM induces apoptosis of the human melanoma SK-Mel-28, but not the mutant Moj-NN nor the non-mutated recombinant Moj-WN.Cloning, expression, and hemostatic activities of a disintegrin, r-mojastin 1, from the mohave rattlesnake (Crotalus scutulatus scutulatus).Functional analysis of a recombinant PIII-SVMP, GST-acocostatin; an apoptotic inducer of HUVEC and HeLa, but not SK-Mel-28 cellsMorulustatin, A Disintegrin that Inhibits ADP-Induced Platelet Aggregation, Isolated from the Mexican Tamaulipan Rock Rattlesnake (Crotalus lepidus morulus).Recombinant rubistatin (r-Rub), an MVD disintegrin, inhibits cell migration and proliferation, and is a strong apoptotic inducer of the human melanoma cell line SK-Mel-28.Impairment of the cell-to-matrix adhesion and cytotoxicity induced by the Mediterranean jellyfish Pelagia noctiluca venom and its fractions in cultured glioblastoma cellscDNA cloning of a snake venom metalloproteinase from the eastern diamondback rattlesnake (Crotalus adamanteus), and the expression of its disintegrin domain with anti-platelet effects.Anti-metastatic activity of the recombinant disintegrin, r-mojastin 1, from the Mohave rattlesnakeTwo Chitotriose-Specific Lectins Show Anti-Angiogenesis, Induces Caspase-9-Mediated Apoptosis and Early Arrest of Pancreatic Tumor Cell Cycle.Inhibition of melanoma cell motility by the snake venom disintegrin eristostatinLaminin-511: a multi-functional adhesion protein regulating cell migration, tumor invasion and metastasis.Effect of the disintegrin eristostatin on melanoma-natural killer cell interactionsQuantitative analysis of snake venoms using soluble polymer-based isotope labeling.Integrins: signaling, disease, and therapy.Rational design of a protein that binds integrin αvβ3 outside the ligand binding site.Inhibition of neutrophil function by two tick salivary proteinsAnti-invasive and anti-adhesive activities of a recombinant disintegrin, r-viridistatin 2, derived from the Prairie rattlesnake (Crotalus viridis viridis).Functional analysis of four single (RGDWL, RGDWM, RGDWP, RGDMN) and two double (RGDNM, RGDMP) mutants: The importance of methionine (M) in the functional potency of recombinant mojastin (r-Moj)The role of integrins in cancer and the development of anti-integrin therapeutic agents for cancer therapy.The binding effectiveness of anti-r-disintegrin polyclonal antibodies against disintegrins and PII and PIII metalloproteases: An immunological survey of type A, B and A+B venoms from Mohave rattlesnakes.Structure and function of snake venom proteins affecting platelet plug formation.ADAM-15 disintegrin-like domain structure and function.Functional characterization of six aspartate (D) recombinant mojastin mutants (r-Moj): A second aspartate amino acid carboxyl to the RGD in r-Moj-D_ peptides is not sufficient to induce apoptosis of SK-Mel-28 cells.Integrin-dependent response to laminin-511 regulates breast tumor cell invasion and metastasis.Venom-based peptide therapy: insights into anti-cancer mechanism.Pyrosequencing the salivary transcriptome ofHaemadipsa interrupta(Annelida: Clitellata: Haemadipsidae): anticoagulant diversity and insight into the evolution of anticoagulation capabilities in leechesRecombinant and Chimeric Disintegrins in Preclinical Research
P2860
Q26740611-0788D2AD-110B-4FB1-828C-EDBF95160466Q27000037-82ADEE9E-B4B6-4859-BD31-D586CC0F7B26Q27324506-651C65E7-D00B-4710-9244-E589EDE02F08Q27674048-E36127A7-0890-4210-B638-14E11DFFFD87Q28818821-20A5940D-75A8-43C1-BD30-F219DBF2F7D3Q33326923-4087B152-04FF-4688-8C85-23FF5DC866EAQ33407731-1C045F81-39D6-449B-93F0-82083DA558C3Q33530304-BD8BB0EB-2954-4097-841E-A2C35BFF5BEBQ33554510-0421FC10-0BEC-44B7-8077-3D236F96F71BQ33558005-3E03CD8C-32E0-4E3E-83BA-043CFE664099Q33624340-9CC1404F-5174-45B2-95AB-0079690D26BEQ33800091-6965138B-A2CE-43A7-A01E-3569CE973649Q33902280-2290D4A4-9D80-4A2B-9BD0-A6FDF5CB41A4Q34109116-32E23705-194A-4B2C-929F-A53B50AF054AQ34319898-579D5EFD-466C-4817-BD78-FDB1B95E49E2Q34546426-A6E30F6A-F335-4C1B-9D68-58D2F34B2AE1Q35801679-A1180B6F-5277-469C-AA60-4FD92612715DQ35900162-679186DB-FAC6-487F-8EDC-C1A71E8B1740Q35940293-4805062B-92AA-4821-B338-9D19650F3D08Q36531794-D45BEC32-79A9-43B9-AA48-9CB9F25A4910Q36677452-9A042857-9EC9-4F80-A313-AF7C722E4F5CQ36685013-74DFAEFD-BFE8-48B7-A3DB-B672E7A29B37Q36939598-847052AD-AECB-4C9A-8873-1DB6A931C490Q36974007-DC258FBD-DC01-424A-BA79-6B3A13D18586Q37204467-105A6FE0-5D26-44CB-932E-BD3A50D5DAFAQ37418714-74FE30A4-EBD8-48D6-B47A-B493F7E4DACCQ37523297-14BF0ED8-CBEE-40EB-B47C-50458CC9D988Q37604903-3E2C5666-7FEB-468A-99DD-00D6BDE777EFQ37716297-F4181EC2-0C45-4EE5-8554-805F56037967Q37954266-B9B195A9-F3CE-4267-9EA7-F30EE67A82B3Q37954269-EFB696B5-2AA0-416C-A259-2921A9993463Q38776214-D93C13CE-55E5-4BC0-A23F-050A02F513B6Q39579106-3FD11447-6CDC-4BA1-991B-FECE8865F1C8Q49215171-19CE7DDE-BF68-47CB-8996-73D701453651Q57833657-3C48A590-8509-4C30-B55B-F5E664AB152BQ58796867-7E8D00C3-767E-4EA1-B782-01C1064D2205
P2860
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Disintegrins
@ast
Disintegrins
@en
Disintegrins
@nl
type
label
Disintegrins
@ast
Disintegrins
@en
Disintegrins
@nl
prefLabel
Disintegrins
@ast
Disintegrins
@en
Disintegrins
@nl
P2093
P3181
P356
P1476
Disintegrins
@en
P2093
Alice Wong
Carrie Paquette-Straub
Elda E Sanchez
John C Perez
Mary Ann McLane
P304
P3181
P356
10.2174/1568006043335880
P407
P577
2004-12-01T00:00:00Z