Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome - Test2 - elhamkhani - TriplyDB

Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome

Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome

http://www.wikidata.org/entity/Q28297967

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Cholangiocarcinoma Vascular patterning sets the stage for macro and micro hepatic architecture Sox9b is a key regulator of pancreaticobiliary ductal system development Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancer Notch signaling in human development and disease Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome Jagged1 (JAG1): Structure, expression, and disease associations Testosterone levels influence mouse fetal Leydig cell progenitors through notch signaling.Angiocrine factors deployed by tumor vascular niche induce B cell lymphoma invasiveness and chemoresistance Hippo pathway activity influences liver cell fate.Molecular pathogenesis of cholangiocarcinoma.Pathogenesis, diagnosis, and management of cholangiocarcinoma Vascular smooth muscle Notch signals regulate endothelial cell sensitivity to angiogenic stimulation.Cholangiocarcinoma: molecular pathways and therapeutic opportunities Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.Evidence against a stem cell origin of new hepatocytes in a common mouse model of chronic liver injury.Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway.Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane.LKB1 and Notch Pathways Interact and Control Biliary Morphogenesis.Functional and structural features of cholangiocytes in health and disease.Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease.Cholangiocarcinomas can originate from hepatocytes in mice.Jagged1 heterozygosity in mice results in a congenital cholangiopathy which is reversed by concomitant deletion of one copy of Poglut1 (Rumi)Molecular basis for Jagged-1/Serrate ligand recognition by the Notch receptor Hepatic stellate cells in liver development, regeneration, and cancer.Recent advances in vascular development.Targeting of the pulmonary capillary vascular niche promotes lung alveolar repair and ameliorates fibrosis.Oncogenic role of the Notch pathway in primary liver cancer.Histology Atlas of the Developing Mouse Hepatobiliary Hemolymphatic Vascular System with Emphasis on Embryonic Days 11.5-18.5 and Early Postnatal Development LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development.Notch signaling regulates tubular morphogenesis during repair from biliary damage in mice.Regulation of pre-natal circle of Willis assembly by vascular smooth muscle Notch signaling Meta-analysis identifies gene-by-environment interactions as demonstrated in a study of 4,965 mice.Development of the bile ducts: essentials for the clinical hepatologist.Differentiation of progenitors in the liver: a matter of local choice Renal involvement and the role of Notch signalling in Alagille syndrome.Molecular mechanisms of liver and bile duct development.Vascular biology of the biliary epithelium

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Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome

http://www.wikidata.org/entity/Q28297967

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

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2010年论文

@wuu

name

Jagged1 in the portal vein mes ...... nsights into Alagille syndrome

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Jagged1 in the portal vein mes ...... nsights into Alagille syndrome

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Jagged1 in the portal vein mes ...... nsights into Alagille syndrome

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type

label

Jagged1 in the portal vein mes ...... nsights into Alagille syndrome

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Jagged1 in the portal vein mes ...... nsights into Alagille syndrome

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Jagged1 in the portal vein mes ...... nsights into Alagille syndrome

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prefLabel

Jagged1 in the portal vein mes ...... nsights into Alagille syndrome

@ast

Jagged1 in the portal vein mes ...... nsights into Alagille syndrome

@en

Jagged1 in the portal vein mes ...... nsights into Alagille syndrome

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Jagged1 in the portal vein mes ...... nsights into Alagille syndrome

@en

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Ann C Zovein

http://www.w3.org/2001/XMLSchema#string

Gerry Weinmaster

http://www.w3.org/2001/XMLSchema#string

Huilin Koh

http://www.w3.org/2001/XMLSchema#string

Jennifer J Hofmann

http://www.w3.org/2001/XMLSchema#string

M Luisa Iruela-Arispe

http://www.w3.org/2001/XMLSchema#string

P2860

NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway

Mutations in the human Jagged1 gene are responsible for Alagille syndrome

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

Identification and cloning of the human homolog (JAG1) of the rat Jagged1 gene from the Alagille syndrome critical region at 20p12

JAGGED1 expression in human embryos: correlation with the Alagille syndrome phenotype

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

Generalized lacZ expression with the ROSA26 Cre reporter strain

Notch signaling: cell fate control and signal integration in development

A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency

Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development

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4061-4072

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scholarly article

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350278

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10.1242/DEV.052118

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23

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137

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47729285

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21062863

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2976287

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