Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders
about
The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5qMutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldismHuman proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligandFMS mutations in myelodysplastic, leukemic, and normal subjectsLoss of both CSF1R (FMS) alleles in patients with myelodysplasia and a chromosome 5 deletioncDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factorDeletion of IRF-1, mapping to chromosome 5q31.1, in human leukemia and preleukemic myelodysplasiaGenetic and radiation hybrid mapping of the hyperekplexia region on chromosome 5q.Linkage mapping of the human CSF2 and IL3 genesA myeloproliferative disease in two infants associated with eosinophilia and chromosome t(1;5) translocation.Close genetic and physical linkage between the murine haemopoietic growth factor genes GM-CSF and Multi-CSF (IL3).A comprehensive genetic map of murine chromosome 11 reveals extensive linkage conservation between mouse and human.Comparative effects in vivo of recombinant murine interleukin 3, natural murine colony-stimulating factor-1, and recombinant murine granulocyte-macrophage colony-stimulating factor on myelopoiesis in mice.Assignment of CSF-1 to 5q33.1: evidence for clustering of genes regulating hematopoiesis and for their involvement in the deletion of the long arm of chromosome 5 in myeloid disorders.Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family--oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.Cytogenetic study in therapy-related myelodysplastic syndromes (t-MDS) and acute non-lymphocytic leukaemia (t-ANLL)Human preleukaemia: do we have a model?High titer autoantibodies to GM-CSF in patients with AML, CML and MDS are associated with active diseaseCytogenetic characteristics of therapy-related acute nonlymphocytic leukaemia, preleukaemia and acute myeloproliferative syndrome: correlation with clinical data for 61 consecutive cases.Fim-1, Fim-2/c-fms, and Fim-3, three common integration sites of Friend murine leukemia virus in myeloblastic leukemias, map to mouse chromosomes 13, 18, and 3, respectivelyRecent advances in the characterization of genetic factors involved in human susceptibility to infection by schistosomiasis."Replacement" of COOH-terminal truncation of v-fms with c-fms sequences markedly reduces transformation potential.Regulation of expression of human granulocyte/macrophage colony-stimulating factor.Deletion 5q in myelodysplastic syndrome: a paradigm for the study of hemizygous deletions in cancer.Nuclear proteins interacting with the promoter region of the human granulocyte/macrophage colony-stimulating factor gene.An overview of tumor biology.Chromosome maps of man and mouse. IV.Colony-stimulating factors in the pathogenesis and treatment of disease.Dysregulation of growth factor-receptor system in cellular transformation.The role of the colony-stimulating factors in resistance to acute infections.Human cancer and cellular oncogenes.Activation of cellular oncogenes in human and mouse leukemia-lymphomas: spontaneous and induced oncogene expression in murine B lymphocytic neoplasms.The expression of FMS, KIT and FLT3 in hematopoietic malignancies.A frequent EcoRI RFLP demonstrated within the human M-CSF receptor gene (CSFIR).Chromosomal deletions in myelodysplasia.Modulation of cytotoxicity and differentiation-inducing potential of arabinofuranosylcytosine in myeloid leukemia cells by hematopoietic cytokines.Clustering of cytokine genes on mouse chromosome 11.
P2860
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P2860
Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders
description
1986 nî lūn-bûn
@nan
1986 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
name
Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders
@ast
Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders
@en
Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders
@nl
type
label
Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders
@ast
Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders
@en
Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders
@nl
prefLabel
Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders
@ast
Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders
@en
Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders
@nl
P2093
P356
P1433
P1476
Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders
@en
P2093
C A Westbrook
J C Gasson
J D Rowley
M M Le Beau
R A Larson
P356
10.1126/SCIENCE.3484837
P407
P577
1986-02-28T00:00:00Z