The oncogene and developmental regulator EVI1: expression, biochemical properties, and biological functions
about
EVI1 controls proliferation in acute myeloid leukaemia through modulation of miR-1-2The PR/SET domain in PRDM4 is preceded by a zinc knuckleSignificance of oncogenes and tumor suppressor genes in AML prognosis.Hemorheological alterations in sickle cell anemia and their clinical consequences - The role of genetic modulators.PRDM16 expression in the developing mouse embryoOverexpression of EVI1 interferes with cytokinesis and leads to accumulation of cells with supernumerary centrosomes in G0/1 phase.EVI1 activation in blast crisis CML due to juxtaposition to the rare 17q22 partner region as part of a 4-way variant translocation t(9;22).Mutations in MECOM, Encoding Oncoprotein EVI1, Cause Radioulnar Synostosis with Amegakaryocytic ThrombocytopeniaComplex or monosomal karyotype and not blast percentage is associated with poor survival in acute myeloid leukemia and myelodysplastic syndrome patients with inv(3)(q21q26.2)/t(3;3)(q21;q26.2): a Bone Marrow Pathology Group studyPRDM Proteins: Molecular Mechanisms in Signal Transduction and Transcriptional Regulation.A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancerOverexpression of ecotropic viral integration site-1 is a prognostic factor of lung squamous cell cancerFine mapping of the NRG1 Hirschsprung's disease locusAcetylation of the proto-oncogene EVI1 abrogates Bcl-xL promoter binding and induces apoptosisChanges in the gene expression programs of renal mesangial cells during diabetic nephropathyHigh DNA methyltransferase DNMT3B levels: a poor prognostic marker in acute myeloid leukemia.Tissue-specific upregulation of MDS/EVI gene transcripts in the intestine by thyroid hormone during Xenopus metamorphosis.EVI1 inhibits apoptosis induced by antileukemic drugs via upregulation of CDKN1A/p21/WAF in human myeloid cellsMutational landscape of gingivo-buccal oral squamous cell carcinoma reveals new recurrently-mutated genes and molecular subgroups.Cancer gene discovery in mouse and man.Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defectsNovel genetic variants in differentiated thyroid cancer and assessment of the cumulative risk.Down-regulation of EVI1 is associated with epigenetic alterations and good prognosis in patients with acute myeloid leukemiaInfant sex-specific placental cadmium and DNA methylation associations.Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors.Exploratory bioinformatics investigation reveals importance of "junk" DNA in early embryo development.EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylationDisease-specific motifs can be identified in circulating nucleic acids from live elk and cattle infected with transmissible spongiform encephalopathies.Update on genetic and molecular markers associated with myelodysplastic syndromes.Overexpression of Evi-1 oncoprotein represses TGF-β signaling in colorectal cancer.PRDM proteins: important players in differentiation and disease.Histone methylation in myelodysplastic syndromes.Ecotropic viral integration site 1, stem cell self-renewal and leukemogenesis.-7/7q- syndrome in myeloid-lineage hematopoietic malignancies: attempts to understand this complex disease entity.EVI1 promotes tumor growth via transcriptional repression of MS4A3.EVI1 overexpression in distinct subtypes of pediatric acute myeloid leukemia.Enhanced sensitivity to hydrogen peroxide-induced apoptosis in Evi1 transformed Rat1 fibroblasts due to repression of carbonic anhydrase III.Functional features of EVI1 and EVI1Δ324 isoforms of MECOM gene in genome-wide transcription regulation and oncogenicity.Recent advances in elucidating the genetic mechanisms of nephrogenesis using zebrafish.3q26/EVI1 rearrangements in myeloid hemopathies: a cytogenetic review.
P2860
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P2860
The oncogene and developmental regulator EVI1: expression, biochemical properties, and biological functions
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The oncogene and developmental ...... ties, and biological functions
@ast
The oncogene and developmental ...... ties, and biological functions
@en
The oncogene and developmental ...... ties, and biological functions
@nl
type
label
The oncogene and developmental ...... ties, and biological functions
@ast
The oncogene and developmental ...... ties, and biological functions
@en
The oncogene and developmental ...... ties, and biological functions
@nl
prefLabel
The oncogene and developmental ...... ties, and biological functions
@ast
The oncogene and developmental ...... ties, and biological functions
@en
The oncogene and developmental ...... ties, and biological functions
@nl
P1433
P1476
The oncogene and developmental ...... ties, and biological functions
@en
P2093
Rotraud Wieser
P304
P356
10.1016/J.GENE.2007.04.012
P407
P577
2007-07-15T00:00:00Z