about
Phosphorylation: the molecular switch of double-strand break repairKu regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cellsThe mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathwayBeyond DNA repair: DNA-PK function in cancerDiseases associated with defective responses to DNA damagePhosphopeptide interactions with BRCA1 BRCT domains: More than just a motifThe DNA Damage Response: Making It Safe to Play with KnivesThe DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosisThe response to and repair of RAG-mediated DNA double-strand breaksRole of non-homologous end joining in V(D)J recombinationFunctional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombinationDNA-PK target identification reveals novel links between DNA repair signaling and cytoskeletal regulationChemical Inhibitors of Non-Homologous End Joining Increase Targeted Construct Integration in Cryptococcus neoformansMechanisms for Structural Variation in the Human GenomeA noncatalytic function of the ligation complex during nonhomologous end joining.ATM and ATR activities maintain replication fork integrity during SV40 chromatin replication.Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex.Dynamics of the PI3K-like protein kinase members ATM and DNA-PKcs at DNA double strand breaks.Nonhomologous end joining: a good solution for bad endsSCID dogs: similar transplant potential but distinct intra-uterine growth defects and premature replicative senescence compared with SCID mice.Non-homologous end joining: emerging themes and unanswered questions.TRF2/RAP1 and DNA-PK mediate a double protection against joining at telomeric ends.Phosphorylation of histone H2A.X by DNA-dependent protein kinase is not affected by core histone acetylation, but it alters nucleosome stability and histone H1 bindingStructural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a timeMitochondria regulate DNA damage and genomic instability induced by high LET radiation.DNA-PKcs deficiency leads to persistence of oxidatively induced clustered DNA lesions in human tumor cells.Targeting DNA repair pathways for cancer treatment: what's new?Structural dynamics in DNA damage signaling and repairIdentification of a coiled coil in werner syndrome protein that facilitates multimerization and promotes exonuclease processivityCoincident In Vitro Analysis of DNA-PK-Dependent and -Independent Nonhomologous End Joining.Phosphatases in the cellular response to DNA damage.XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair.DNA-PK, ATM and ATR collaboratively regulate p53-RPA interaction to facilitate homologous recombination DNA repairCooperative assembly of a protein-DNA filament for nonhomologous end joiningDNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritisA structural model for regulation of NHEJ by DNA-PKcs autophosphorylationCongenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair.Tandem BRCT Domains: DNA's Praetorian Guard.DNA structure-specific priming of ATR activation by DNA-PKcsChoosing the right path: does DNA-PK help make the decision?
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008 թուականին հրատարակուած գիտական յօդուած
@hyw
2008 թվականին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
DNA-PK: the means to justify the ends?
@ast
DNA-PK: the means to justify the ends?
@en
DNA-PK: the means to justify the ends?
@nl
type
label
DNA-PK: the means to justify the ends?
@ast
DNA-PK: the means to justify the ends?
@en
DNA-PK: the means to justify the ends?
@nl
prefLabel
DNA-PK: the means to justify the ends?
@ast
DNA-PK: the means to justify the ends?
@en
DNA-PK: the means to justify the ends?
@nl
P2093
P3181
P1476
DNA-PK: the means to justify the ends?
@en
P2093
Katheryn Meek
Susan P Lees-Miller
P3181
P356
10.1016/S0065-2776(08)00602-0
P407
P577
2008-01-01T00:00:00Z