about
The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activityA novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexesDisruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and miceARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7, in vitroPitchfork regulates primary cilia disassembly and left-right asymmetryIntegrative analysis of the mitochondrial proteome in yeastSuccessful subretinal delivery and monitoring of MicroBeads in miceActive transport and diffusion barriers restrict Joubert Syndrome-associated ARL13B/ARL-13 to an Inv-like ciliary membrane subdomainPitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway ActivationKIAA0556 is a novel ciliary basal body component mutated in Joubert syndromeStructural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Marius Ueffing
@ast
Marius Ueffing
@en
Marius Ueffing
@es
Marius Ueffing
@nl
Marius Ueffing
@sl
type
label
Marius Ueffing
@ast
Marius Ueffing
@en
Marius Ueffing
@es
Marius Ueffing
@nl
Marius Ueffing
@sl
prefLabel
Marius Ueffing
@ast
Marius Ueffing
@en
Marius Ueffing
@es
Marius Ueffing
@nl
Marius Ueffing
@sl