Torsades de pointes occurring in association with terfenadine use
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Role of cytochrome P450 in drug interactionsInvolvement of multiple human cytochromes P450 in the liver microsomal metabolism of astemizole and a comparison with terfenadineGrapefruit juice-drug interactionsMethodological considerations in the design of trials for safety assessment of new drugs and chemical entitiesVentricular repolarization measures for arrhythmic risk stratificationTowards a better understanding of QT interval variabilityDrug-drug interactions and QT prolongation as a commonly assessed cardiac effect - comprehensive overview of clinical trialsRisk of ventricular arrhythmias associated with nonsedating antihistamine drugsInhibition of HERG1 K(+) channels by the novel second-generation antihistamine mizolastineTorsades de pointes after terfenadine-itraconazole interactionSingle Doses up to 800 mg of E-52862 Do Not Prolong the QTc Interval--A Retrospective Validation by Pharmacokinetic-Pharmacodynamic Modelling of Electrocardiography Data Utilising the Effects of a Meal on QTc to Demonstrate ECG Assay SensitivityComputational tools and resources for metabolism-related property predictions. 1. Overview of publicly available (free and commercial) databases and softwareThe use of pharmacokinetic and pharmacodynamic data in the assessment of drug safety in early drug developmentFamilial and acquired long qt syndrome and the cardiac rapid delayed rectifier potassium current.Possible interactions with terfenadine or astemizoleA Bayesian meta-analysis on published sample mean and variance pharmacokinetic data with application to drug-drug interaction predictionVoriconazole associated torsades de pointes in two adult patients with haematological malignancies.The association between pro-arrhythmic agents and aortic stenosis in young adults: is it sufficient to clarify the sudden unexpected deaths?Differences and similarities between chronic obstructive pulmonary disease and asthma.Drug-induced QT interval prolongation: mechanisms and clinical managementCardiovascular safety of antihistamines.Examining the utilization and tolerability of the non-sedating antihistamine levocetirizine in England using prescription-event monitoring data.Drug-induced long QT syndromeRepurposing the antihistamine terfenadine for antimicrobial activity against Staphylococcus aureus.Understanding and preventing drug-drug and drug-gene interactions.The significance of QT interval in drug development.Clinical relevance and management of drug-related QT interval prolongation.Long-term bradycardia caused by atrioventricular block can remodel the canine heart to detect the histamine H1 blocker terfenadine-induced torsades de pointes arrhythmias.QTc prolongation assessment in anticancer drug development: clinical and methodological issuesNon-sedating antihistamine drugs and cardiac arrhythmias -- biased risk estimates from spontaneous reporting systems?Pharmacokinetics and electrocardiographic pharmacodynamics of artemether-lumefantrine (Riamet) with concomitant administration of ketoconazole in healthy subjects.Cardiac safety, drug-induced QT prolongation and torsade de pointes (TdP).Potential depot medroxyprogesterone acetate-triggered torsades de pointes in a case of congenital type 2 long QT syndromeLong QT syndrome: reduced repolarization reserve and the genetic link.Role of biotransformation in drug-induced toxicity: influence of intra- and inter-species differences in drug metabolism.Suppression of phosphoinositide 3-kinase signaling and alteration of multiple ion currents in drug-induced long QT syndromePrevalence of potential drug interactions in an Iranian general hospital.Extracellular sodium interacts with the HERG channel at an outer pore site.Drug-induced arrhythmia: pharmacogenomic prescribing?Antidepressant-drug interactions are potentially but rarely clinically significant.
P2860
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P2860
Torsades de pointes occurring in association with terfenadine use
description
1990 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of the American Medical Association
@fr
artículu científicu espublizáu en 1990
@ast
im Dezember 1990 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 5 December 1990)
@en
vedecký článok (publikovaný 1990/12/05)
@sk
vědecký článek publikovaný v roce 1990
@cs
wetenschappelijk artikel (gepubliceerd op 1990/12/05)
@nl
наукова стаття, опублікована в грудні 1990
@uk
name
Torsades de pointes occurring in association with terfenadine use
@ast
Torsades de pointes occurring in association with terfenadine use
@en
Torsades de pointes occurring in association with terfenadine use
@nl
type
label
Torsades de pointes occurring in association with terfenadine use
@ast
Torsades de pointes occurring in association with terfenadine use
@en
Torsades de pointes occurring in association with terfenadine use
@nl
prefLabel
Torsades de pointes occurring in association with terfenadine use
@ast
Torsades de pointes occurring in association with terfenadine use
@en
Torsades de pointes occurring in association with terfenadine use
@nl
P2093
P3181
P356
P1476
Torsades de pointes occurring in association with terfenadine use
@en
P2093
B P Monahan
C L Ferguson
E S Killeavy
L R Cantilena
P304
P3181
P356
10.1001/JAMA.264.21.2788
P407
P577
1990-12-05T00:00:00Z