PTP-PEST, a scaffold protein tyrosine phosphatase, negatively regulates lymphocyte activation by targeting a unique set of substrates
about
Proline-serine-threonine phosphatase interacting proteinĀ 1 inhibition of T-cell receptor signaling depends on its SH3 domainLeupaxin negatively regulates B cell receptor signalingPositive and negative regulation of T-cell activation through kinases and phosphatasesProtein tyrosine phosphatases expression during development of mouse superior colliculusNitric oxide-induced inhibition of aortic smooth muscle cell motility: role of PTP-PEST and adaptor proteins p130cas and CrkProtein tyrosine phosphatases and the immune responseComparison of T cell receptor-induced proximal signaling and downstream functions in immortalized and primary T cellsThe PTB domain of ShcA couples receptor activation to the cytoskeletal regulator IQGAP1Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptorEmbryonal Fyn-associated substrate (EFS) and CASS4: The lesser-known CAS protein family membersRegulation of the Src kinase-associated phosphoprotein 55 homologue by the protein tyrosine phosphatase PTP-PEST in the control of cell motilityThe autoimmunity risk variant LYP-W620 cooperates with CSK in the regulation of TCR signaling.Caspase-3 regulates catalytic activity and scaffolding functions of the protein tyrosine phosphatase PEST, a novel modulator of the apoptotic response.Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation.Phosphorylation of paxillin at threonine 538 by PKCdelta regulates LFA1-mediated adhesion of lymphoid cells.RETRACTED: Silencing of B cell receptor signals in human naive B cells.Clinical, Molecular, and Genetic Characteristics of PAPA Syndrome: A Review.A loss-of-function screen for phosphatases that regulate neurite outgrowth identifies PTPN12 as a negative regulator of TrkB tyrosine phosphorylation.CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cellsRole of protein tyrosine phosphatases in T cell activation.Ras-induced and extracellular signal-regulated kinase 1 and 2 phosphorylation-dependent isomerization of protein tyrosine phosphatase (PTP)-PEST by PIN1 promotes FAK dephosphorylation by PTP-PEST.Central role of paxillin phosphorylation in regulation of LFA-1 integrins activity and lymphocyte migration.The balance of expression of PTPN22 splice forms is significantly different in rheumatoid arthritis patients compared with controls.Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity.Loss of PTPN12 Stimulates Progression of ErbB2-Dependent Breast Cancer by Enhancing Cell Survival, Migration, and Epithelial-to-Mesenchymal TransitionEssential function of PTP-PEST during mouse embryonic vascularization, mesenchyme formation, neurogenesis and early liver development.The phosphatase PTP-PEST/PTPN12 regulates endothelial cell migration and adhesion, but not permeability, and controls vascular development and embryonic viabilityPhosphatase regulation of immunoreceptor signaling in T cells, B cells and mast cells.The Leishmania surface protease GP63 cleaves multiple intracellular proteins and actively participates in p38 mitogen-activated protein kinase inactivation.TCR-induced downregulation of protein tyrosine phosphatase PEST augments secondary T cell responsesFAK phosphorylation by ERK primes ras-induced tyrosine dephosphorylation of FAK mediated by PIN1 and PTP-PESTRegulation of tumor cell migration by protein tyrosine phosphatase (PTP)-proline-, glutamate-, serine-,and threonine-rich sequence (PEST).Phosphatase regulation of intercellular junctions.Regulation of TCR signalling by tyrosine phosphatases: from immune homeostasis to autoimmunity.Teaching an old dogma new tricks: twenty years of Shc adaptor signalling.Does B cell receptor signaling in chronic lymphocytic leukaemia cells differ from that in other B cell types?Signaling mechanisms regulating B-lymphocyte activation and tolerance.Deficiency in VHR/DUSP3, a suppressor of focal adhesion kinase, reveals its role in regulating cell adhesion and migration.Reduced FAK-STAT3 signaling contributes to ER stress-induced mitochondrial dysfunction and death in endothelial cells.The Tyrosine Kinome Dictates Breast Cancer Heterogeneity and Therapeutic Responsiveness.
P2860
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P2860
PTP-PEST, a scaffold protein tyrosine phosphatase, negatively regulates lymphocyte activation by targeting a unique set of substrates
description
2001 nĆ® lÅ«n-bĆ»n
@nan
2001 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« Õ
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@hyw
2001 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Õ°ÕøÖÕ¬Õ«Õ½Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
2001幓ć®č«ę
@ja
2001幓č«ę
@yue
2001幓č«ę
@zh-hant
2001幓č«ę
@zh-hk
2001幓č«ę
@zh-mo
2001幓č«ę
@zh-tw
2001幓č®ŗę
@wuu
name
PTP-PEST, a scaffold protein t ...... ing a unique set of substrates
@ast
PTP-PEST, a scaffold protein t ...... ing a unique set of substrates
@en
PTP-PEST, a scaffold protein t ...... ing a unique set of substrates
@nl
type
label
PTP-PEST, a scaffold protein t ...... ing a unique set of substrates
@ast
PTP-PEST, a scaffold protein t ...... ing a unique set of substrates
@en
PTP-PEST, a scaffold protein t ...... ing a unique set of substrates
@nl
prefLabel
PTP-PEST, a scaffold protein t ...... ing a unique set of substrates
@ast
PTP-PEST, a scaffold protein t ...... ing a unique set of substrates
@en
PTP-PEST, a scaffold protein t ...... ing a unique set of substrates
@nl
P2860
P356
P1433
P1476
PTP-PEST, a scaffold protein t ...... ing a unique set of substrates
@en
P2093
A Veillette
D Davidson
P2860
P304
P356
10.1093/EMBOJ/20.13.3414
P407
P577
2001-07-01T00:00:00Z