The complexity of KIT gene mutations and chromosome rearrangements and their clinical correlation in gastrointestinal stromal (pacemaker cell) tumors
about
Targeted mutations of the juxtamembrane tyrosines in the Kit receptor tyrosine kinase selectively affect multiple cell lineagesChromosome copy number changes carry prognostic information independent of KIT/PDGFRA point mutations in gastrointestinal stromal tumorsc-Kit expression, angiogenesis, and grading in canine mast cell tumour: a unique model to study c-Kit driven human malignancies.Gastrointestinal stromal tumors (GIST): C-kit mutations, CD117 expression, differential diagnosis and targeted cancer therapy with Imatinib.Surgery and imatinib in the management of GIST: emerging approaches to adjuvant and neoadjuvant therapy.Recent advances in the understanding of mastocytosis: the role of KIT mutations.GIST: an update.Gleevec: prototype or outlier?An update on molecular genetics of gastrointestinal stromal tumours.Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation.Clinical manifestations and prognostic factors in patients with gastrointestinal stromal tumorsC-kit gene mutation in human gastrointestinal stromal tumors.Expression and mutation of c-kit gene in gastrointestinal stromal tumorsMultiple gastric stromal tumors in a child without syndromic association lacks common KIT or PDGFRalpha mutations.Spectral karyotyping of human, mouse, rat and ape chromosomes--applications for genetic diagnostics and research.Neoadjuvant, adjuvant and palliative treatment of gastrointestinal stromal tumours (GIST) with imatinib: a centre-based study of 17 patients.Interstitial cells of Cajal in health and disease. Part II: ICC and gastrointestinal stromal tumours.Molecular approaches to resolve diagnostic dilemmas: the case of gastrointestinal stromal tumor and leiomyosarcoma.Subepithelial mass lesions in the upper gastrointestinal tract.Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumours.Identification of c-kit gene mutations in primary adenoid cystic carcinoma of the salivary gland.KIT exon 11 codon 557/558 deletion/insertion mutations define a subset of gastrointestinal stromal tumors with malignant potential.Gastrointestinal stromal tumor and its mimics.Multiple novel alterations in Kit tyrosine kinase in patients with gastrointestinally pronounced systemic mast cell activation disorder.KIT gene mutations in gastrointestinal stromal tumors: more complex than previously recognized?Apparent KIT Ser(715) deletion in GIST mRNA is not detectable in genomic DNA and represents a previously known splice variant of KIT transcript.Dramatic response of a gastrointestinal stromal tumor to neadjuvant imatinib therapy.[Pathology and molecular biology of gastrointestinal stromal tumors (GIST)].Deletion of Trp-557 and Lys-558 in the juxtamembrane domain of the c-kit protooncogene is associated with metastatic behavior of gastrointestinal stromal tumors.c-kit and SCF expression in normal and tumor breast tissue.The identification and characterisation of novel KIT transcripts in aggressive mast cell malignancies and normal CD34+ cells.Expression of c-kit in fibroepithelial lesions of the breast is a mast cell phenomenon.Follow-up of gastro-intestinal stromal tumours (GIST) during treatment with imatinib mesylate by abdominal MRI.Inactivating Mutations of RB1 and TP53 Correlate With Sarcomatous Histomorphology and Metastasis/Recurrence in Gastrointestinal Stromal Tumors.Clinical implications of C-kit gene mutation in patients with large gastrointestinal stromal tumors.Differential diagnosis of gastrointestinal leiomyoma versus gastrointestinal stromal tumor.Two different KIT mutations may lead to different responses to imatinib in metastatic gastrointestinal stromal tumor.
P2860
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P2860
The complexity of KIT gene mutations and chromosome rearrangements and their clinical correlation in gastrointestinal stromal (pacemaker cell) tumors
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2002 nî lūn-bûn
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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2002 թվականի հունվարին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
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name
The complexity of KIT gene mut ...... tromal (pacemaker cell) tumors
@ast
The complexity of KIT gene mut ...... tromal (pacemaker cell) tumors
@en
The complexity of KIT gene mut ...... tromal (pacemaker cell) tumors
@nl
type
label
The complexity of KIT gene mut ...... tromal (pacemaker cell) tumors
@ast
The complexity of KIT gene mut ...... tromal (pacemaker cell) tumors
@en
The complexity of KIT gene mut ...... tromal (pacemaker cell) tumors
@nl
prefLabel
The complexity of KIT gene mut ...... tromal (pacemaker cell) tumors
@ast
The complexity of KIT gene mut ...... tromal (pacemaker cell) tumors
@en
The complexity of KIT gene mut ...... tromal (pacemaker cell) tumors
@nl
P2093
P2860
P1476
The complexity of KIT gene mut ...... tromal (pacemaker cell) tumors
@en
P2093
Göran Stenman
Helene Sjögren
Jeanne M Meis-Kindblom
Johanna Andersson
P2860
P356
10.1016/S0002-9440(10)64343-X
P407
P577
2002-01-01T00:00:00Z