Increased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseases
about
Trans-4-hydroxy-2-nonenal inhibits nucleotide excision repair in human cells: a possible mechanism for lipid peroxidation-induced carcinogenesisHFE C282Y and H63D in adults with malignancies in a community medical oncology practiceThe Stereochemistry of trans -4-Hydroxynonenal-Derived Exocyclic 1, N 2 -2′-Deoxyguanosine Adducts Modulates Formation of Interstrand Cross-Links in the 5′-CpG-3′ Sequence †Conformational Interconversion of the trans -4-Hydroxynonenal-Derived (6 S ,8 R ,11 S ) 1, N 2 -Deoxyguanosine Adduct When Mismatched with Deoxyadenosine in DNAReplication Bypass of the trans -4-Hydroxynonenal-Derived (6 S ,8 R ,11 S )-1, N 2 -Deoxyguanosine DNA Adduct by the Sulfolobus solfataricus DNA Polymerase IVDietary iron overload in the African and hepatocellular carcinoma4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathwayElevated copper remodels hepatic RNA processing machinery in the mouse model of Wilson's diseaseThe "two-faced" effects of reactive oxygen species and the lipid peroxidation product 4-hydroxynonenal in the hallmarks of cancerThe effect of zinc and the role of p53 in copper-induced cellular stress responses.Repair kinetics of trans-4-hydroxynonenal-induced cyclic 1,N2-propanodeoxyguanine DNA adducts by human cell nuclear extractsClinical outcomes and correlates of TP53 mutations and cancer.8-Hydroxydeoxyguanosine: a new potential independent prognostic factor in breast cancer.Nitric oxide: perspectives and emerging studies of a well known cytotoxinAcetaldehyde adducts in alcoholic liver disease.The core control system of intracellular iron homeostasis: a mathematical model.P53 mutations in thyroid carcinoma: tidings from an old foe.Redox regulation of apurinic/apyrimidinic endonuclease 1 activity in Long-Evans Cinnamon rats during spontaneous hepatitisNitric oxide-induced cellular stress and p53 activation in chronic inflammationThe p53 tumor suppressor network is a key responder to microenvironmental components of chronic inflammatory stress.S-nitrosylation from GSNOR deficiency impairs DNA repair and promotes hepatocarcinogenesisRegulation of DNA repair by S-nitrosylation.N-hydroxylation of 4-aminobiphenyl by CYP2E1 produces oxidative stress in a mouse model of chemically induced liver cancer.Stress-induced corneal epithelial apoptosis mediated by K+ channel activationHFE gene mutations in susceptibility to childhood leukemia: HuGE review.The point mutation of p53 gene exon7 in hepatocellular carcinoma from Anhui Province, a non HCC prevalent area in China.DNA sequence context effects on the glycosylase activity of human 8-oxoguanine DNA glycosylase.Hepatocarcinogenesis driven by GSNOR deficiency is prevented by iNOS inhibition.Suppression of tumor suppressor Tsc2 and DNA repair glycosylase Nth1 during spontaneous liver tumorigenesis in Long-Evans Cinnamon rats.Protein expression profiling of nuclear membrane protein reveals potential biomarker of human hepatocellular carcinomaAcrolein-derived DNA adduct formation in human colon cancer cells: its role in apoptosis induction by docosahexaenoic acid.Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.Aging and inflammation: etiological culprits of cancerNitric oxide and redox regulation in the liver: part II. Redox biology in pathologic hepatocytes and implications for intervention.DNA cross-link induced by trans-4-hydroxynonenal.Redox modulation of p53: mechanisms and functional significance.Chemistry and structural biology of DNA damage and biological consequencesCellular and molecular mechanisms of hepatocellular carcinoma: an update.MicroRNAs and liver cancer associated with iron overload: therapeutic targets unravelled.Copper alters the conformation and transcriptional activity of the tumor suppressor protein p53 in human Hep G2 cells.
P2860
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P2860
Increased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseases
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2000 nî lūn-bûn
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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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Increased p53 mutation load in ...... : oxyradical overload diseases
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Increased p53 mutation load in ...... : oxyradical overload diseases
@en
Increased p53 mutation load in ...... : oxyradical overload diseases
@nl
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label
Increased p53 mutation load in ...... : oxyradical overload diseases
@ast
Increased p53 mutation load in ...... : oxyradical overload diseases
@en
Increased p53 mutation load in ...... : oxyradical overload diseases
@nl
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Increased p53 mutation load in ...... : oxyradical overload diseases
@ast
Increased p53 mutation load in ...... : oxyradical overload diseases
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Increased p53 mutation load in ...... : oxyradical overload diseases
@nl
P2093
P2860
P356
P1476
Increased p53 mutation load in ...... : oxyradical overload diseases
@en
P2093
A J Marrogi
C C Harris
C Trautwein
D H Phillips
L J Hofseth
L J Trudel
P A Amstad
P2860
P304
P356
10.1073/PNAS.220416097
P407
P577
2000-11-07T00:00:00Z