Insulin-induced cortical actin remodeling promotes GLUT4 insertion at muscle cell membrane ruffles
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SKIP negatively regulates insulin-induced GLUT4 translocation and membrane ruffle formation.Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes.Lipid Raft targeting of the TC10 amino terminal domain is responsible for disruption of adipocyte cortical actinAn actin filament population defined by the tropomyosin Tpm3.1 regulates glucose uptakeRac1 signaling is required for insulin-stimulated glucose uptake and is dysregulated in insulin-resistant murine and human skeletal muscleInsulin stimulates movement of sorting nexin 9 between cellular compartments: a putative role mediating cell surface receptor expression and insulin actionProtein kinase Czeta mediates insulin-induced glucose transport through actin remodeling in L6 muscle cellsMyo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesiclesArp2/3- and cofilin-coordinated actin dynamics is required for insulin-mediated GLUT4 translocation to the surface of muscle cellsRab8A and Rab13 are activated by insulin and regulate GLUT4 translocation in muscle cellsCortactin, an actin binding protein, regulates GLUT4 translocation via actin filament remodelingInsulin-induced endothelial cell cortical actin filament remodeling: a requirement for trans-endothelial insulin transport.Insulin signaling diverges into Akt-dependent and -independent signals to regulate the recruitment/docking and the fusion of GLUT4 vesicles to the plasma membraneIdentification of a distal GLUT4 trafficking event controlled by actin polymerizationKinetics of contraction-induced GLUT4 translocation in skeletal muscle fibers from living mice.Myosin IIB and F-actin control apical vacuolar morphology and histamine-induced trafficking of H-K-ATPase-containing tubulovesicles in gastric parietal cells.Unconventional myosin Myo1c promotes membrane fusion in a regulated exocytic pathway.Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling.PKC-induced intracellular trafficking of Ca(V)2 precedes its rapid recruitment to the plasma membrane.Glucose lowering effect of transgenic human insulin-like growth factor-I from rice: in vitro and in vivo studiesDynamin-2 mutations linked to Centronuclear Myopathy impair actin-dependent trafficking in muscle cells.Bioactives from Artemisia dracunculus L. enhance insulin sensitivity via modulation of skeletal muscle protein phosphorylationMyo1c regulates glucose uptake in mouse skeletal muscle.Nexilin, a cardiomyopathy-associated F-actin binding protein, binds and regulates IRS1 signaling in skeletal muscle cells.Nef inhibits glucose uptake in adipocytes and contributes to insulin resistance in human immunodeficiency virus type I infection.Subcellular trafficking of the substrate transporters GLUT4 and CD36 in cardiomyocytesIntracellular segregation of phosphatidylinositol-3,4,5-trisphosphate by insulin-dependent actin remodeling in L6 skeletal muscle cellsIdentification of P-Rex1 as a novel Rac1-guanine nucleotide exchange factor (GEF) that promotes actin remodeling and GLUT4 protein trafficking in adipocytesGLUT4 exocytosis.Regulation of glucose transport by ROCK1 differs from that of ROCK2 and is controlled by actin polymerizationβ(2)-Adrenoceptors increase translocation of GLUT4 via GPCR kinase sites in the receptor C-terminal tail.Turning down insulin signaling.Insulin signaling and the regulation of glucose transport.Rac-mediated actin remodeling and myosin II are involved in KATP channel trafficking in pancreatic β-cells."Actin"g on GLUT4: membrane & cytoskeletal components of insulin action.Disruption of cortical actin in skeletal muscle demonstrates an essential role of the cytoskeleton in glucose transporter 4 translocation in insulin-sensitive tissues.Loss of cortical actin filaments in insulin-resistant skeletal muscle cells impairs GLUT4 vesicle trafficking and glucose transport.Phosphoinositides in insulin action on GLUT4 dynamics: not just PtdIns(3,4,5)P3.Septin 7 reduces nonmuscle myosin IIA activity in the SNAP23 complex and hinders GLUT4 storage vesicle docking and fusion.Insulin and hypertonicity recruit GLUT4 to the plasma membrane of muscle cells by using N-ethylmaleimide-sensitive factor-dependent SNARE mechanisms but different v-SNAREs: role of TI-VAMP.
P2860
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P2860
Insulin-induced cortical actin remodeling promotes GLUT4 insertion at muscle cell membrane ruffles
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Insulin-induced cortical actin ...... t muscle cell membrane ruffles
@ast
Insulin-induced cortical actin ...... t muscle cell membrane ruffles
@en
Insulin-induced cortical actin ...... t muscle cell membrane ruffles
@nl
type
label
Insulin-induced cortical actin ...... t muscle cell membrane ruffles
@ast
Insulin-induced cortical actin ...... t muscle cell membrane ruffles
@en
Insulin-induced cortical actin ...... t muscle cell membrane ruffles
@nl
prefLabel
Insulin-induced cortical actin ...... t muscle cell membrane ruffles
@ast
Insulin-induced cortical actin ...... t muscle cell membrane ruffles
@en
Insulin-induced cortical actin ...... t muscle cell membrane ruffles
@nl
P2093
P2860
P356
P1476
Insulin-induced cortical actin ...... t muscle cell membrane ruffles
@en
P2093
P2860
P304
P356
10.1172/JCI12348
P407
P577
2001-08-01T00:00:00Z