Functionalized congeners of adenosine: preparation of analogues with high affinity for A1-adenosine receptors
about
Binary drugs: conjugates of purines and a peptide that bind to both adenosine and substance P receptorsElectrophilic derivatives of purines as irreversible inhibitors of A1 adenosine receptorsAdenosine receptor prodrugs: towards kidney-selective dialkylxanthinesFunctionalized congeners of 1,3-dipropyl-8-phenylxanthine: potent antagonists for adenosine receptors that modulate membrane adenylate cyclase in pheochromocytoma cells, platelets and fat cellsAdenosine analogs with covalently attached lipids have enhanced potency at A1-adenosine receptorsPharmacokinetic Properties of Adenosine Amine Congener in Cochlear Perilymph after Systemic AdministrationPHOTOLABILE A1-ADENOSINE RECEPTOR AGONISTS AS "CAGED" ELECTROPHYSIOLOGICAL PROBESSynthesis and biological activity of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine: water-soluble and peripherally selective adenosine agonistsAdenosine amine congener as a cochlear rescue agent.Adenosine amine congener mitigates noise-induced cochlear injuryA novel cardioprotective function of adenosine A1 and A3 receptors during prolonged simulated ischemia.Functionalized congener approach to the design of ligands for G protein-coupled receptors (GPCRs).XAC, a functionalized congener of 1,3-dialkylxanthine, antagonizes A1 adenosine receptor-mediated inhibition of renin secretion in vitro.Evidence that a novel 8-phenyl-substituted xanthine derivative is a cardioselective adenosine receptor antagonist in vivo.Agonist derived molecular probes for A2 adenosine receptorsN6-functionalized congeners of adenosine with high potency at A2-adenosine receptors: potential ligands for affinity chromatography.[3H]xanthine amine congener of 1,3-dipropyl-8-phenylxanthine: an antagonist radioligand for adenosine receptors.Adenosine A1 and A2 receptors: structure--function relationshipsA2A adenosine receptors from rat striatum and rat pheochromocytoma PC12 cells: characterization with radioligand binding and by activation of adenylate cyclase.Molecular probes for extracellular adenosine receptors.Characterization of human striatal A2-adenosine receptors using radioligand binding and photoaffinity labelingA PROSTHETIC GROUP FOR THE RAPID INTRODUCTION OF FLUORINE INTO PEPTIDES AND FUNCTIONALIZED DRUGS.Postischemic administration of adenosine amine congener (ADAC): analysis of recovery in gerbilsAdenosine receptor prodrugs: synthesis and biological activity of derivatives of potent, A1-selective agonistsA functionalized congener approach to adenosine receptor antagonists: amino acid conjugates of 1,3-dipropylxanthine.Functionalized congeners of 1,3-dialkylxanthines: preparation of analogues with high affinity for adenosine receptors.Species differences in structure-activity relationships of adenosine agonists and xanthine antagonists at brain A1 adenosine receptors.A novel pharmacological approach to treating cardiac ischemia. Binary conjugates of A1 and A3 adenosine receptor agonists.Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists.Enhanced A3 adenosine receptor selectivity of multivalent nucleoside-dendrimer conjugates.Application of the functionalized congener approach to dendrimer-based signaling agents acting through A(2A) adenosine receptors.Quantitative analysis of the formation and diffusion of A1-adenosine receptor-antagonist complexes in single living cells.Comparative molecular field analysis of selective A3 adenosine receptor agonists.Adenosine A1 receptor agonists as clinically viable agents for treatment of ischemic brain disorders.Adenosine derivatives with N6-alkyl, -alkylamine or -alkyladenosine substituents as probes for the A1-receptor.Improvement of cold tolerance by selective A1 adenosine receptor antagonists in rats.
P2860
Q28338174-E491B9A9-EC06-4B7B-A08D-7DCB5321FDD5Q28356112-2C3CB028-0C4D-4A05-BDD1-EA623F93529FQ28358958-1C324DC2-E67D-4915-916D-AAD7101E1F5EQ28360371-D70FA836-D770-4254-93CB-0C7629E2822EQ28361997-66E14BAB-2CB7-4E65-8E06-00AF5FBE6330Q30363358-9111BB14-A03C-4E2E-9F40-F6F836774239Q30384330-89C32B5F-BAEE-4904-95C8-994FCC158BC4Q30425523-39E8AA99-F670-4D24-99E3-EDB0EE0CA372Q30430524-AADD769A-BF8F-45CC-B0D7-02D9F0F75C06Q30479856-234CF2CB-B6C3-4052-984F-A114C49FE31FQ33797566-1A3E1F85-A1BF-4C35-A4B2-86BCE237C63BQ33926350-EC16CB66-9029-4669-9C70-E55C9B29A58FQ35024951-658F23A1-FF6E-4CE8-A6B8-B4B79CD90B00Q35153363-3A447076-A51C-4A42-B2E2-86479E060FE5Q35170171-17B5BC68-990A-4174-A9BB-3554F803B280Q35191322-6A5D98F7-07D8-4397-BB5C-0E2EF98CA4F0Q35609958-47FB2000-A455-4D28-9B17-9B75B68551B8Q35766866-9ED5FA9E-766C-4BB0-A620-49A355D89012Q35911207-7AC1DF15-82DE-4FF0-A74D-381168A518F9Q36072729-D070DA6A-4A21-415B-98DC-034BA9DE18B3Q36194316-0CF0B74F-3406-4577-AA84-DF140DCF49BEQ36224436-E8B59AAE-0349-4405-9035-A4A587C671D3Q36253704-F3166F67-EADB-4983-8ED9-8FE9799ABCD8Q36281936-1AFC3020-1AC1-4C33-8B9A-AFE8BFE39947Q36282911-6F58BAB7-7A8F-40BA-BB6A-533C39668586Q36308784-71E90084-EA46-43A2-BB9F-67F58C92F942Q36311732-62359251-3BF0-465C-845A-C64A9F321B0DQ36580219-1AAEFBBD-C0A9-4235-929C-6B4FC3E47E3CQ36725267-5910A04F-4553-4B5B-92FF-899298FA6112Q36970794-7228DB21-EB3A-4512-8FD1-BDE3121A0BB4Q37291594-393B51F3-41A4-4E3D-AD5B-F2CDC164B8E9Q37358468-EF70C4AA-6B25-40C1-B4E4-6B465FEBEFAAQ41316766-8784C64E-D220-4055-9C43-6EA7C22FA98EQ41643075-EA07110A-F922-49BE-ADA5-1307073D62F3Q42204092-E848F424-3E8E-4C5A-B7B7-3DF119F0E53FQ42393484-CE5A90E7-B484-4521-B494-061F58BE4A48
P2860
Functionalized congeners of adenosine: preparation of analogues with high affinity for A1-adenosine receptors
description
1985 nî lūn-bûn
@nan
1985 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1985 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
name
Functionalized congeners of ad ...... ity for A1-adenosine receptors
@ast
Functionalized congeners of ad ...... ity for A1-adenosine receptors
@en
Functionalized congeners of ad ...... ity for A1-adenosine receptors
@nl
type
label
Functionalized congeners of ad ...... ity for A1-adenosine receptors
@ast
Functionalized congeners of ad ...... ity for A1-adenosine receptors
@en
Functionalized congeners of ad ...... ity for A1-adenosine receptors
@nl
prefLabel
Functionalized congeners of ad ...... ity for A1-adenosine receptors
@ast
Functionalized congeners of ad ...... ity for A1-adenosine receptors
@en
Functionalized congeners of ad ...... ity for A1-adenosine receptors
@nl
P2093
P2860
P356
P1476
Functionalized congeners of ad ...... ity for A1-adenosine receptors
@en
P2093
K A Jacobson
W L Padgett
P2860
P304
P356
10.1021/JM00147A039
P407
P577
1985-09-01T00:00:00Z