Selective deletion of leptin receptor in neurons leads to obesity - Test2 - elhamkhani - TriplyDB

Selective deletion of leptin receptor in neurons leads to obesity

Selective deletion of leptin receptor in neurons leads to obesity

http://www.wikidata.org/entity/Q28361816

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Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41 Recent advances in understanding leptin signaling and leptin resistance Neuropeptide Y in normal eating and in genetic and dietary-induced obesity Lean heart: Role of leptin in cardiac hypertrophy and metabolism Control of metabolic and cardiovascular function by the leptin-brain melanocortin pathway Central nervous system mechanisms linking the consumption of palatable high-fat diets to the defense of greater adiposity Central nervous control of energy and glucose balance: focus on the central melanocortin system Leptin action in pubertal development: recent advances and unanswered questions Leptin in pregnancy and development: a contributor to adulthood disease?Fatty acid binding receptors and their physiological role in type 2 diabetes Nutrigenomic analysis of diet-gene interactions on functional supplements for weight management Targeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesity Leptin-inhibited PBN neurons enhance responses to hypoglycemia in negative energy balance Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation The cellular and molecular bases of leptin and ghrelin resistance in obesity.Leptin receptor null mice with reexpression of LepR in GnRHR expressing cells display elevated FSH levels but remain in a prepubertal state Disruption in the leptin-NPY link underlies the pandemic of diabetes and metabolic syndrome: new therapeutic approaches Cross-Talk between Metabolism and Reproduction: The Role of POMC and SF1 Neurons Leptin signaling in intestinal epithelium mediates resistance to enteric infection by Entamoeba histolytica.Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons.PET imaging of leptin biodistribution and metabolism in rodents and primates.Forebrain glutamatergic neurons mediate leptin action on depression-like behaviors and synaptic depression Analysis of N-glycan in serum glycoproteins from db/db mice and humans with type 2 diabetes.Obesity-induced hepatic steatosis is mediated by endoplasmic reticulum stress in the subfornical organ of the brain Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation.The role of leptin in glucose homeostasis.Leptin and the systems neuroscience of meal size control.Utility of transplantation in studying adipocyte biogenesis and function Minireview: Metabolism of female reproduction: regulatory mechanisms and clinical implications Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons.Functional role of suppressor of cytokine signaling 3 upregulation in hypothalamic leptin resistance and long-term energy homeostasis.Melanocortin-3 receptors and metabolic homeostasis.Leptin- and leptin receptor-deficient rodent models: relevance for human type 2 diabetes.An intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorption A leptin-mediated central mechanism in analgesia-enhanced opioid reward in rats A role of phosphodiesterase-3B pathway in mediating leptin action on proopiomelanocortin and neurotensin neurons in the hypothalamus.Systemic leptin dose-dependently increases STAT3 phosphorylation within hypothalamic and hindbrain nuclei.Leptin functions peripherally to regulate differentiation of mesenchymal progenitor cells.Leptin-receptor-expressing mesenchymal stromal cells represent the main source of bone formed by adult bone marrow.Disruption of hypothalamic leptin signaling in mice leads to early-onset obesity, but physiological adaptations in mature animals stabilize adiposity levels

P2860

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P2860

Selective deletion of leptin receptor in neurons leads to obesity

http://www.wikidata.org/entity/Q28361816

description

2001 nî lūn-bûn

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2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

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2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

Selective deletion of leptin receptor in neurons leads to obesity

@ast

Selective deletion of leptin receptor in neurons leads to obesity

@en

Selective deletion of leptin receptor in neurons leads to obesity

@nl

type

label

Selective deletion of leptin receptor in neurons leads to obesity

@ast

Selective deletion of leptin receptor in neurons leads to obesity

@en

Selective deletion of leptin receptor in neurons leads to obesity

@nl

prefLabel

Selective deletion of leptin receptor in neurons leads to obesity

@ast

Selective deletion of leptin receptor in neurons leads to obesity

@en

Selective deletion of leptin receptor in neurons leads to obesity

@nl

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Journal of Clinical Investigation

P1476

Selective deletion of leptin receptor in neurons leads to obesity

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P2093

C Zhao

http://www.w3.org/2001/XMLSchema#string

J M Friedman

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J M Montez

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P Cohen

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P Feinstein

http://www.w3.org/2001/XMLSchema#string

P Mombaerts

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S C Rohani

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X Cai

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P2860

Positional cloning of the mouse obese gene and its human homologue

Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein

Hypothalamic CART is a new anorectic peptide regulated by leptin

Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass

Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain

Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

Leptin and the regulation of body weight in mammals

Weight-reducing effects of the plasma protein encoded by the obese gene

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1113-21

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3308044

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10.1172/JCI13914

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8

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