Selective deletion of leptin receptor in neurons leads to obesity
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Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41Recent advances in understanding leptin signaling and leptin resistanceNeuropeptide Y in normal eating and in genetic and dietary-induced obesityLean heart: Role of leptin in cardiac hypertrophy and metabolismControl of metabolic and cardiovascular function by the leptin-brain melanocortin pathwayCentral nervous system mechanisms linking the consumption of palatable high-fat diets to the defense of greater adiposityCentral nervous control of energy and glucose balance: focus on the central melanocortin systemLeptin action in pubertal development: recent advances and unanswered questionsLeptin in pregnancy and development: a contributor to adulthood disease?Fatty acid binding receptors and their physiological role in type 2 diabetesNutrigenomic analysis of diet-gene interactions on functional supplements for weight managementTargeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesityLeptin-inhibited PBN neurons enhance responses to hypoglycemia in negative energy balanceDisruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulationThe cellular and molecular bases of leptin and ghrelin resistance in obesity.Leptin receptor null mice with reexpression of LepR in GnRHR expressing cells display elevated FSH levels but remain in a prepubertal stateDisruption in the leptin-NPY link underlies the pandemic of diabetes and metabolic syndrome: new therapeutic approachesCross-Talk between Metabolism and Reproduction: The Role of POMC and SF1 NeuronsLeptin signaling in intestinal epithelium mediates resistance to enteric infection by Entamoeba histolytica.Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons.PET imaging of leptin biodistribution and metabolism in rodents and primates.Forebrain glutamatergic neurons mediate leptin action on depression-like behaviors and synaptic depressionAnalysis of N-glycan in serum glycoproteins from db/db mice and humans with type 2 diabetes.Obesity-induced hepatic steatosis is mediated by endoplasmic reticulum stress in the subfornical organ of the brainEndogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation.The role of leptin in glucose homeostasis.Leptin and the systems neuroscience of meal size control.Utility of transplantation in studying adipocyte biogenesis and functionMinireview: Metabolism of female reproduction: regulatory mechanisms and clinical implicationsSegregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons.Functional role of suppressor of cytokine signaling 3 upregulation in hypothalamic leptin resistance and long-term energy homeostasis.Melanocortin-3 receptors and metabolic homeostasis.Leptin- and leptin receptor-deficient rodent models: relevance for human type 2 diabetes.An intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorptionA leptin-mediated central mechanism in analgesia-enhanced opioid reward in ratsA role of phosphodiesterase-3B pathway in mediating leptin action on proopiomelanocortin and neurotensin neurons in the hypothalamus.Systemic leptin dose-dependently increases STAT3 phosphorylation within hypothalamic and hindbrain nuclei.Leptin functions peripherally to regulate differentiation of mesenchymal progenitor cells.Leptin-receptor-expressing mesenchymal stromal cells represent the main source of bone formed by adult bone marrow.Disruption of hypothalamic leptin signaling in mice leads to early-onset obesity, but physiological adaptations in mature animals stabilize adiposity levels
P2860
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P2860
Selective deletion of leptin receptor in neurons leads to obesity
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Selective deletion of leptin receptor in neurons leads to obesity
@ast
Selective deletion of leptin receptor in neurons leads to obesity
@en
Selective deletion of leptin receptor in neurons leads to obesity
@nl
type
label
Selective deletion of leptin receptor in neurons leads to obesity
@ast
Selective deletion of leptin receptor in neurons leads to obesity
@en
Selective deletion of leptin receptor in neurons leads to obesity
@nl
prefLabel
Selective deletion of leptin receptor in neurons leads to obesity
@ast
Selective deletion of leptin receptor in neurons leads to obesity
@en
Selective deletion of leptin receptor in neurons leads to obesity
@nl
P2093
P2860
P3181
P1476
Selective deletion of leptin receptor in neurons leads to obesity
@en
P2093
J M Friedman
J M Montez
P Feinstein
P Mombaerts
S C Rohani
P2860
P304
P3181
P356
10.1172/JCI13914
10.1172/JCI200113914
P407
P577
2001-10-01T00:00:00Z