A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells
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Neural tube defects and folate: case far from closedBiomarkers of Nutrition for Development-Folate ReviewNovel Approaches to Investigate One-Carbon Metabolism and Related B-Vitamins in Blood PressureHomocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication biasNo effect of folic acid supplementation on global DNA methylation in men and women with moderately elevated homocysteineMutated 5,10-methylenetetrahydrofolate reductase, hyperhomocysteinemia and risk for cardiovascular disease. Nature, nurture or nonsense?Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms and therapy-related toxicity in children treated for acute lymphoblastic leukemia and non-Hodgkin lymphoma.Preliminary evidence for cell membrane amelioration in children with cystic fibrosis by 5-MTHF and vitamin B12 supplementation: a single arm trial.A hybrid stochastic model of folate-mediated one-carbon metabolism: Effect of the common C677T MTHFR variant on de novo thymidylate biosynthesisGenetic and lifestyle variables associated with homocysteine concentrations and the distribution of folate derivatives in healthy premenopausal women.Stable-isotope dilution LC–MS for quantitative biomarker analysis.Targeted metabolomics and mathematical modeling demonstrate that vitamin B-6 restriction alters one-carbon metabolism in cultured HepG2 cells.Maternal MTHFR genotype and haplotype predict deficits in early cognitive development in a lead-exposed birth cohort in Mexico CityPharmacogenetics research on chemotherapy resistance in colorectal cancer over the last 20 yearsA common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status.Folate status assessment history: implications for measurement of biomarkers in NHANESMaternal methylenetetrahydrofolate reductase C677T polymorphism and down syndrome risk: a meta-analysis from 34 studiesSingle nucleotide polymorphisms of one-carbon metabolism and cancers of the esophagus, stomach, and liver in a Chinese population.Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects.The association between MTHFR gene polymorphisms and hepatocellular carcinoma risk: a meta-analysis.Polymorphisms in folate-metabolizing enzymes and response to 5-fluorouracil among patients with stage II or III rectal cancer (INT-0144; SWOG 9304).Role of the MTHFR polymorphisms in cancer risk modification and treatment.Pharmacogenetics and folate metabolism -- a promising direction.Individualization of thiopurine therapy: thiopurine S-methyltransferase and beyond.Methionine synthase reductase deficiency results in adverse reproductive outcomes and congenital heart defects in mice.Determination of unmetabolized folic acid in human plasma using affinity HPLC.Biomarkers of folate status in NHANES: a roundtable summaryQuantification of key red blood cell folates from subjects with defined MTHFR 677C>T genotypes using stable isotope dilution liquid chromatography/mass spectrometry.Is there more to folates than neural-tube defects?Insights into metabolic mechanisms underlying folate-responsive neural tube defects: a minireview.Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer.Routine storage of red blood cell (RBC) units in additive solution-3: a comprehensive investigation of the RBC metabolome.The methylenetetrahydrofolate reductase 677C-->T polymorphism as a modulator of a B vitamin network with major effects on homocysteine metabolism.5,10-methylenetetrahydrofolate reductase 677 and 1298 polymorphisms, folate intake, and microsatellite instability in colon cancerHomocysteine Metabolism Gene Polymorphisms (MTHFR C677T, MTHFR A1298C, MTR A2756G and MTRR A66G) Jointly Elevate the Risk of Folate DeficiencyAssociation of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study.Pharmacogenetics of folate-related drug targets in cancer treatment.Methylenetetrahydrofolate reductase C677T polymorphism and breast cancer risk in Moroccan women.Sensitivity of markers of DNA stability and DNA repair activity to folate supplementation in healthy volunteersNeither folic acid supplementation nor pregnancy affects the distribution of folate forms in the red blood cells of women
P2860
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P2860
A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
A common mutation in the methy ...... ydrofolates in red blood cells
@ast
A common mutation in the methy ...... ydrofolates in red blood cells
@en
A common mutation in the methy ...... ydrofolates in red blood cells
@nl
type
label
A common mutation in the methy ...... ydrofolates in red blood cells
@ast
A common mutation in the methy ...... ydrofolates in red blood cells
@en
A common mutation in the methy ...... ydrofolates in red blood cells
@nl
prefLabel
A common mutation in the methy ...... ydrofolates in red blood cells
@ast
A common mutation in the methy ...... ydrofolates in red blood cells
@en
A common mutation in the methy ...... ydrofolates in red blood cells
@nl
P2860
P356
P1476
A common mutation in the methy ...... ydrofolates in red blood cells
@en
P2093
P2860
P304
13217-13220
P356
10.1073/PNAS.95.22.13217
P407
P577
1998-10-01T00:00:00Z