Mutations in haemagglutinin that affect receptor binding and pH stability increase replication of a PR8 influenza virus with H5 HA in the upper respiratory tract of ferrets and may contribute to transmissibility

Mutations in haemagglutinin that affect receptor binding and pH stability increase replication of a PR8 influenza virus with H5 HA in the upper respiratory tract of ferrets and may contribute to transmissibility

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http://www.wikidata.org/entity/Q28385604

Q28385604

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One health, multiple challenges: The inter-species transmission of influenza A virus Molecular requirements for a pandemic influenza virus: An acid-stable hemagglutinin protein Airborne transmission of highly pathogenic H7N1 influenza virus in ferrets Influenza A virus transmission via respiratory aerosols or droplets as it relates to pandemic potential Mammalian Pathogenesis and Transmission of H7N9 Influenza Viruses from Three Waves, 2013-2015 Avian influenza A viruses: from zoonosis to pandemic Viral factors in influenza pandemic risk assessment.Ethical alternatives to experiments with novel potential pandemic pathogens.One-way trip: influenza virus' adaptation to gallinaceous poultry may limit its pandemic potential.Pseudotype-based neutralization assays for influenza: a systematic analysis.The ethics of biosafety considerations in gain-of-function research resulting in the creation of potential pandemic pathogens.H1N1 Swine Influenza Viruses Differ from Avian Precursors by a Higher pH Optimum of Membrane Fusion.Constitutively Expressed IFITM3 Protein in Human Endothelial Cells Poses an Early Infection Block to Human Influenza Viruses.H1N1 influenza viruses varying widely in hemagglutinin stability transmit efficiently from swine to swine and to ferrets.Variability in H9N2 haemagglutinin receptor-binding preference and the pH of fusion A novel A(H7N2) influenza virus isolated from a veterinarian caring for cats in a New York City animal shelter causes mild disease and transmits poorly in the ferret model.Increased acid stability of the hemagglutinin protein enhances H5N1 influenza virus growth in the upper respiratory tract but is insufficient for transmission in ferrets.Glycomic characterization of respiratory tract tissues of ferrets: implications for its use in influenza virus infection studies Role of receptor binding specificity in influenza A virus transmission and pathogenesis.Identification, characterization, and natural selection of mutations driving airborne transmission of A/H5N1 virus.Crucial role of PA in virus life cycle and host adaptation of influenza A virus.Genetic Adaptation of Influenza A Viruses in Domestic Animals and Their Potential Role in Interspecies Transmission: A Literature Review.Amino Acid Substitutions That Affect Receptor Binding and Stability of the Hemagglutinin of Influenza A/H7N9 Virus.A novel eight amino acid insertion contributes to the hemagglutinin cleavability and the virulence of a highly pathogenic avian influenza A (H7N3) virus in mice.Influenza hemagglutinin (HA) stem region mutations that stabilize or destabilize the structure of multiple HA subtypes Modulating secretory pathway pH by proton channel co-expression can increase recombinant protein stability in plants.Influenza Hemagglutinin Protein Stability, Activation, and Pandemic Risk.Evaluation of antiviral activity of Ocimum sanctum and Acacia arabica leaves extracts against H9N2 virus using embryonated chicken egg model.Retroviral Pseudotypes - From Scientific Tools to Clinical Utility The application of pseudotypes to influenza pandemic preparedness

P2860

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P2860

Mutations in haemagglutinin that affect receptor binding and pH stability increase replication of a PR8 influenza virus with H5 HA in the upper respiratory tract of ferrets and may contribute to transmissibility

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http://www.wikidata.org/entity/Q28385604

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2013 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2013 թվականի հունիսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年论文

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