Soluble epoxide hydrolase: a novel therapeutic target in stroke - Test2 - elhamkhani - TriplyDB

Soluble epoxide hydrolase: a novel therapeutic target in stroke

Soluble epoxide hydrolase: a novel therapeutic target in stroke

http://www.wikidata.org/entity/Q28388145

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Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases Arachidonic acid cytochrome P450 epoxygenase pathway Mechanism of the sex difference in endothelial dysfunction after stroke Removal of distal protein-water hydrogen bonds in a plant epoxide hydrolase increases catalytic turnover but decreases thermostability The role of long chain fatty acids and their epoxide metabolites in nociceptive signaling The role of epoxyeicosatrienoic acids in the cardiovascular system The Natural Flavonoid Pinocembrin: Molecular Targets and Potential Therapeutic Applications Cyclooxygenase- and cytochrome P450-derived eicosanoids in stroke Mammalian soluble epoxide hydrolase is identical to liver hepoxilin hydrolase Estrogen, aging and the cardiovascular system Genetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese population Soluble epoxide hydrolase activity determines the severity of ischemia-reperfusion injury in kidney Soluble epoxide hydrolase gene deletion reduces survival after cardiac arrest and cardiopulmonary resuscitation Possible role of Epoxyeicosatrienoic acid in prevention of oxidative stress mediated neuroinflammation in Parkinson disorders Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia Red blood cells (RBCs), epoxyeicosatrienoic acids (EETs) and adenosine triphosphate (ATP)Heavy chain single-domain antibodies to detect native human soluble epoxide hydrolase Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammation Genetic variation in soluble epoxide hydrolase: association with outcome after aneurysmal subarachnoid hemorrhage Soluble Epoxide Hydrolase Inhibition: Targeting Multiple Mechanisms of Ischemic Brain Injury with a Single Agent Inhibition of soluble epoxide hydrolase does not protect against endotoxin-mediated hepatic inflammation Sex- and isoform-specific mechanism of neuroprotection by transgenic expression of P450 epoxygenase in vascular endothelium Soluble epoxide hydrolase inhibition modulates vascular remodeling Epoxyeicosanoid signaling in CNS function and disease Disrupting Dimerization Translocates Soluble Epoxide Hydrolase to Peroxisomes Soluble epoxide hydrolase in atherosclerosis Cytochrome P450 eicosanoids and cerebral vascular function Pharmacokinetic screening of soluble epoxide hydrolase inhibitors in dogs Renal Ischemia/Reperfusion Injury in Soluble Epoxide Hydrolase-Deficient Mice Effect of 20-HETE inhibition on infarct volume and cerebral blood flow after transient middle cerebral artery occlusion.Epoxyeicosanoids as mediators of neurogenic vasodilation in cerebral vessels.Role of soluble epoxide hydrolase in the sex-specific vascular response to cerebral ischemia.Mechanism of protection by soluble epoxide hydrolase inhibition in type 2 diabetic stroke Dose-dependent effects of androgens on outcome after focal cerebral ischemia in adult male mice.Inhibition of soluble epoxide hydrolase by trans-4- [4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is protective against ischemia-reperfusion injury.Oxidation of the endogenous cannabinoid arachidonoyl ethanolamide by the cytochrome P450 monooxygenases: physiological and pharmacological implications.Intrarenal cytochrome P-450 metabolites of arachidonic acid in the regulation of the nonclipped kidney function in two-kidney, one-clip Goldblatt hypertensive rats.Testosterone deficiency accelerates neuronal and vascular aging of SAMP8 mice: protective role of eNOS and SIRT1 Role of epoxyeicosatrienoic acids as autocrine metabolites in glutamate-mediated K+ signaling in perivascular astrocytes.The inhibitor of 20-HETE synthesis, TS-011, improves cerebral microcirculatory autoregulation impaired by middle cerebral artery occlusion in mice.

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P2860

Soluble epoxide hydrolase: a novel therapeutic target in stroke

http://www.wikidata.org/entity/Q28388145

description

2007 nî lūn-bûn

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2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Soluble epoxide hydrolase: a novel therapeutic target in stroke

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Soluble epoxide hydrolase: a novel therapeutic target in stroke

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Soluble epoxide hydrolase: a novel therapeutic target in stroke

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Soluble epoxide hydrolase: a novel therapeutic target in stroke

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SJ.JCBFM.9600494

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Journal of Cerebral Blood Flow & Metabolism

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Soluble epoxide hydrolase: a novel therapeutic target in stroke

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Hsing-Ju Tsai

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Ines P Koerner

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John R Falck

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Marjorie Grafe

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Nabil J Alkayed

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Ruediger Noppens

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Wenri Zhang

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P2860

Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study

The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity

Epoxide hydrolases: their roles and interactions with lipid metabolism

Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway

Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids.

Soluble epoxide hydrolase in rat inflammatory cells is indistinguishable from soluble epoxide hydrolase in rat liver

Soluble epoxide hydrolase is a therapeutic target for acute inflammation

Cytochrome p450 epoxygenase metabolism of arachidonic acid inhibits apoptosis

Identification and characterisation of soluble epoxide hydrolase in mouse brain by a robust protein biochemical method.

Polymorphism in soluble epoxide hydrolase and blood pressure in spontaneously hypertensive rats.

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1931-40

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1481285

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10.1038/SJ.JCBFM.9600494

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12

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Christophe Morisseau

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2007-12-01T00:00:00Z

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6389097

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17440491

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2664093

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