Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pat
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Present Advances and Future Perspectives of Molecular Targeted Therapy for OsteosarcomaThe dark side of ZNF217, a key regulator of tumorigenesis with powerful biomarker valueInhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells.Aurora-A affects radiosenstivity in cervical squamous cell carcinoma and predicts poor prognosis.Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells.Aurora A Kinase Inhibitor AKI603 Induces Cellular Senescence in Chronic Myeloid Leukemia Cells Harboring T315I Mutation.Aurora kinase A revives dormant laryngeal squamous cell carcinoma cells via FAK/PI3K/Akt pathway activation.Diosmetin inhibits cell proliferation and induces apoptosis by regulating autophagy via the mammalian target of rapamycin pathway in hepatocellular carcinoma HepG2 cells.The inhibition of lung cancer cell migration by AhR-regulated autophagy.The Aurora kinase A inhibitor TC-A2317 disrupts mitotic progression and inhibits cancer cell proliferation.Domain-specific interactions between MLN8237 and human serum albumin estimated by STD and WaterLOGSY NMR, ITC, spectroscopic, and docking techniques.Alisertib induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt/mTOR- and p38 MAPK-mediated pathways in human glioblastoma cellsThe Aurora kinase inhibitors in cancer research and therapy.EMMPRIN, SP1 and microRNA-27a mediate physcion 8-O-β-glucopyranoside-induced apoptosis in osteosarcoma cells.Aberrant expression of microRNA-99a and its target gene mTOR associated with malignant progression and poor prognosis in patients with osteosarcoma.A SILAC-based proteomics elicits the molecular interactome of alisertib (MLN8237) in human erythroleukemia K562 cells.A proteomics-based investigation on the anticancer activity of alisertib, an Aurora kinase A inhibitor, in hepatocellular carcinoma Hep3B cells.Knockdown of SIRT1 Suppresses Bladder Cancer Cell Proliferation and Migration and Induces Cell Cycle Arrest and Antioxidant Response through FOXO3a-Mediated Pathways.Ginsenoside Rg3 Suppresses Proliferation and Induces Apoptosis in Human Osteosarcoma.
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P2860
Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pat
description
2015 nî lūn-bûn
@nan
2015 թուականին հրատարակուած գիտական յօդուած
@hyw
2015 թվականին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
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name
Pro-apoptotic and pro-autophag ...... PK/PI3K/Akt/mTOR signaling pat
@nl
type
label
Pro-apoptotic and pro-autophag ...... PK/PI3K/Akt/mTOR signaling pat
@nl
prefLabel
Pro-apoptotic and pro-autophag ...... PK/PI3K/Akt/mTOR signaling pat
@nl
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Pro-apoptotic and pro-autophag ...... I3K/Akt/mTOR signaling pathway
@en
P2093
Giang H T Au
Guozhi Xiao
Hui-Qiang Ding
Jia-Xuan Qiu
Ning-Kui Niu
Shu-Feng Zhou
Shu-Ting Pan
Tianxin Yang
Xiao-Wu Chen
Xueji Zhang
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P304
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10.2147/DDDT.S74197
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P577
2015-01-01T00:00:00Z