Systemic administration of antiretrovirals prior to exposure prevents rectal and intravenous HIV-1 transmission in humanized BLT mice - Test2 - elhamkhani - TriplyDB

Systemic administration of antiretrovirals prior to exposure prevents rectal and intravenous HIV-1 transmission in humanized BLT mice

Systemic administration of antiretrovirals prior to exposure prevents rectal and intravenous HIV-1 transmission in humanized BLT mice

http://www.wikidata.org/entity/Q28472590

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Human breast milk and antiretrovirals dramatically reduce oral HIV-1 transmission in BLT humanized mice Tuberculosis and HIV co-infection In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells Animal and human mucosal tissue models to study HIV biomedical interventions: can we predict success?Animal models to study Mycobacterium tuberculosis and HIV co-infection Studies of retroviral infection in humanized mice Advances in HIV microbicide development Animal models in HIV cure research New generation humanized mice for virus research: comparative aspects and future prospects Nanoformulations of Rilpivirine for Topical Pericoital and Systemic Coitus-Independent Administration Efficiently Prevent HIV Transmission A humanized mouse model of tuberculosis Immune reconstitution of the female reproductive tract of humanized BLT mice and their susceptibility to human immunodeficiency virus infection.Stampidine as a promising antiretroviral drug candidate for pre-exposure prophylaxis against sexually transmitted HIV/AIDS A topical microbicide gel formulation of CCR5 antagonist maraviroc prevents HIV-1 vaginal transmission in humanized RAG-hu mice Rectal transmission of transmitted/founder HIV-1 is efficiently prevented by topical 1% tenofovir in BLT humanized mice In vivo analysis of highly conserved Nef activities in HIV-1 replication and pathogenesis.Overlapping effector interfaces define the multiple functions of the HIV-1 Nef polyproline helix.Eradication therapies for HIV Infection: time to begin again.Animal models for HIV/AIDS research Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice Oral pre-exposure prophylaxis by anti-retrovirals raltegravir and maraviroc protects against HIV-1 vaginal transmission in a humanized mouse model.Humanized Rag1-/- γc-/- mice support multilineage hematopoiesis and are susceptible to HIV-1 infection via systemic and vaginal routes Current humanized mouse models for studying human immunology and HIV-1 immuno-pathogenesis.HIV restriction by APOBEC3 in humanized mice.One percent tenofovir applied topically to humanized BLT mice and used according to the CAPRISA 004 experimental design demonstrates partial protection from vaginal HIV infection, validating the BLT model for evaluation of new microbicide candidates Superior human leukocyte reconstitution and susceptibility to vaginal HIV transmission in humanized NOD-scid IL-2Rγ(-/-) (NSG) BLT mice.The utility of the new generation of humanized mice to study HIV-1 infection: transmission, prevention, pathogenesis, and treatment.Eradicating HIV-1 infection: seeking to clear a persistent pathogen.Hypogammaglobulinemia in BLT humanized mice--an animal model of primary antibody deficiency.Humanized mouse models for HIV-1 infection of the CNS.Generation of HIV latency in humanized BLT mice.Preexposure prophylaxis for HIV prevention.The use of preexposure treatments for HIV prophylaxis Alpha interferon and HIV infection cause activation of human T cells in NSG-BLT mice In vivo analysis of Nef's role in HIV-1 replication, systemic T cell activation and CD4(+) T cell loss.BLT humanized mice as a small animal model of HIV infection.Nef functions in BLT mice to enhance HIV-1 replication and deplete CD4+CD8+ thymocytes.Incorporation of the HIV-1 microbicide cyanovirin-N in a food product.Role of Semen on Vaginal HIV-1 Transmission and Maraviroc Protection.In vivo platforms for analysis of HIV persistence and eradication.

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P2860

Systemic administration of antiretrovirals prior to exposure prevents rectal and intravenous HIV-1 transmission in humanized BLT mice

http://www.wikidata.org/entity/Q28472590

description

2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2010年の論文

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Deborah A Payne

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Francisco Martinez-Torres

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J Victor Garcia

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Jacob D Estes

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John F Krisko

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Melissa Mathias

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Youn Tae Kwak

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P2860

Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice

Post-exposure prophylaxis for SIV revisited: animal model for HIV prevention

The spread, treatment, and prevention of HIV-1: evolution of a global pandemic

The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?

How do viral and host factors modulate the sexual transmission of HIV? Can transmission be blocked?

Global epidemiology of injecting drug use and HIV among people who inject drugs: a systematic review

Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine

Pharmacokinetics, oral bioavailability, and metabolism in mice and cynomolgus monkeys of (2'R,5'S-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, an agent active against human immunodeficiency virus and human hepatitis B virus

Antiretroviral efficacy and pharmacokinetics of oral bis(isopropyloxycarbonyloxymethyl)-9-(2-phosphonylmethoxypropyl)adenine in mice

Criteria for drugs used in pre-exposure prophylaxis trials against HIV infection

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Daniel A Powell

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2010-01-21T00:00:00Z

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41124004

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20098623

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HIV transmission

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2809117

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