Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres
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Finding the end: recruitment of telomerase to telomeresTERRA: telomeric repeat-containing RNAAnalyses of Candida Cdc13 Orthologues Revealed a Novel OB Fold Dimer Arrangement, Dimerization-Assisted DNA Binding, and Substantial Structural Differences between Cdc13 and RPA70Modulation of yeast telomerase activity by Cdc13 and Est1 in vitro.Rvb2/reptin physically associates with telomerase in budding yeast.Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongation.RPA facilitates telomerase activity at chromosome ends in budding and fission yeastsSingle-strand DNA-binding protein SSB1 facilitates TERT recruitment to telomeres and maintains telomere G-overhangsThe Saccharomyces cerevisiae telomerase subunit Est3 binds telomeres in a cell cycle- and Est1-dependent manner and interacts directly with Est1 in vitroThe telomere capping complex CST has an unusual stoichiometry, makes multipartite interaction with G-Tails, and unfolds higher-order G-tail structuresThe TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasisAn RPA-related sequence-specific DNA-binding subunit of telomerase holoenzyme is required for elongation processivity and telomere maintenance.Duplication and functional specialization of the telomere-capping protein Cdc13 in Candida speciesPreserving Yeast Genetic Heritage through DNA Damage Checkpoint Regulation and Telomere Maintenance.Investigating the role of the Est3 protein in yeast telomere replication.Protection and replication of telomeres in fission yeast.Rif1 supports the function of the CST complex in yeast telomere capping.Quantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects.To fuse or not to fuse: how do checkpoint and DNA repair proteins maintain telomeres?The principal role of Ku in telomere length maintenance is promotion of Est1 association with telomeresNormal telomere length maintenance in Saccharomyces cerevisiae requires nuclear import of the ever shorter telomeres 1 (Est1) protein via the importin alpha pathway.Evolution of CST function in telomere maintenance.Telomeres: structures in need of unwinding.A yeast telomerase complex containing the Est1 recruitment protein is assembled early in the cell cycle.Telomerase recruitment in Saccharomyces cerevisiae is not dependent on Tel1-mediated phosphorylation of Cdc13.Analysis of poly(ADP-Ribose) polymerases in Arabidopsis telomere biology.POT1a and components of CST engage telomerase and regulate its activity in Arabidopsis.Tpz1-Ccq1 and Tpz1-Poz1 interactions within fission yeast shelterin modulate Ccq1 Thr93 phosphorylation and telomerase recruitment.The telomeric Cdc13 protein interacts directly with the telomerase subunit Est1 to bring it to telomeric DNA ends in vitro.DNA-end capping by the budding yeast transcription factor and subtelomeric binding protein Tbf1Schizosaccharomyces pombe Ccq1 and TER1 bind the 14-3-3-like domain of Est1, which promotes and stabilizes telomerase-telomere association.Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end.The interaction between the yeast telomerase RNA and the Est1 protein requires three structural elements.Stiffened yeast telomerase RNA supports RNP function in vitro and in vivo.DNA repair at telomeres: keeping the ends intact.Mechanisms that regulate localization of a DNA double-strand break to the nuclear periphery.Telomere length regulation: coupling DNA end processing to feedback regulation of telomerase.The conserved Est1 protein stimulates telomerase DNA extension activity.Telomerase: an RNP enzyme synthesizes DNA.Telomeres and telomerase in Candida albicans.
P2860
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P2860
Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres
@ast
Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres
@en
Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres
@nl
type
label
Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres
@ast
Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres
@en
Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres
@nl
prefLabel
Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres
@ast
Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres
@en
Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres
@nl
P2860
P3181
P1433
P1476
Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres
@en
P2093
Angela Chan
Virginia A Zakian
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1000236
P407
P577
2008-10-24T00:00:00Z