The Caenorhabditis elegans homolog of Gen1/Yen1 resolvases links DNA damage signaling to DNA double-strand break repair
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A role for the malignant brain tumour (MBT) domain protein LIN-61 in DNA double-strand break repair by homologous recombinationA novel role of human holliday junction resolvase GEN1 in the maintenance of centrosome integrityMeiotic development in Caenorhabditis elegansUnpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleasesIntermittent Stem Cell Cycling Balances Self-Renewal and Senescence of the C. elegans Germ LineA new thermosensitive smc-3 allele reveals involvement of cohesin in homologous recombination in C. elegansCombinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleasesJoint molecule resolution requires the redundant activities of MUS-81 and XPF-1 during Caenorhabditis elegans meiosisSynthetic cytotoxicity: digenic interactions with TEL1/ATM mutations reveal sensitivity to low doses of camptothecinProcessing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes.ZTF-8 interacts with the 9-1-1 complex and is required for DNA damage response and double-strand break repair in the C. elegans germline.SLX-1 is required for maintaining genomic integrity and promoting meiotic noncrossovers in the Caenorhabditis elegans germline.DNA double-strand break repair in Caenorhabditis elegansThe EEL-1 ubiquitin ligase promotes DNA damage-induced germ cell apoptosis in C. elegansAtGEN1 and AtSEND1, two paralogs in Arabidopsis, possess holliday junction resolvase activity.A genomic screen revealing the importance of vesicular trafficking pathways in genome maintenance and protection against genotoxic stress in diploid Saccharomyces cerevisiae cellsMRG-1 is required for genomic integrity in Caenorhabditis elegans germ cells.JMJD-5/KDM8 regulates H3K36me2 and is required for late steps of homologous recombination and genome integrity.A genome-wide RNAi screen identifies core components of the G₂-M DNA damage checkpoint.DNA Damage Sensitivity Assays in Caenorhabditis elegans.Pro-crossover factors regulate damage-dependent apoptosis in the Caenorhabditis elegans germ line.X Chromosome Crossover Formation and Genome Stability in Caenorhabditis elegans Are Independently Regulated by xnd-1.E4 ligase-specific ubiquitination hubs coordinate DNA double-strand-break repair and apoptosisEffect of GEN1 interference on the chemosensitivity of the breast cancer MCF-7 and SKBR3 cell lines.Caenorhabditis elegans as a powerful alternative model organism to promote research in genetic toxicology and biomedicine.Holliday junction-resolving enzymes-structures and mechanisms.Prophase I: Preparing Chromosomes for Segregation in the Developing Oocyte.A Role for the Nonsense-Mediated mRNA Decay Pathway in Maintaining Genome Stability in Caenorhabditis elegans.Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA.Methodological considerations for mutagen exposure in C. elegans.GEN1 from a thermophilic fungus is functionally closely similar to non-eukaryotic junction-resolving enzymes.The atm-1 gene is required for genome stability in Caenorhabditis elegansExpression and localization of GEN1 in mouse mammary epithelial cells.Cooperative control of holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases.Caenorhabditis elegans BUB-3 and SAN-1/MAD3 Spindle Assembly Checkpoint Components Are Required for Genome Stability in Response to Treatment with Ionizing Radiation.Resolvase OsGEN1 Mediates DNA Repair by Homologous Recombination.The Structure-Specific Endonucleases MUS81 and SEND1 Are Essential for Telomere Stability in Arabidopsis.Maintenance of Genome Integrity by Mi2 Homologs CHD-3 and LET-418 in Caenorhabditis elegans.Disruption of Gen1 Causes Congenital Anomalies of the Kidney and Urinary Tract in Mice.The conserved LEM-3/Ankle1 nuclease is involved in the combinatorial regulation of meiotic recombination repair and chromosome segregation in Caenorhabditis elegans.
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P2860
The Caenorhabditis elegans homolog of Gen1/Yen1 resolvases links DNA damage signaling to DNA double-strand break repair
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2010 nî lūn-bûn
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2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2010 թվականի հուլիսին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
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2010年論文
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2010年論文
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The Caenorhabditis elegans hom ...... DNA double-strand break repair
@ast
The Caenorhabditis elegans hom ...... DNA double-strand break repair
@en
The Caenorhabditis elegans hom ...... DNA double-strand break repair
@nl
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label
The Caenorhabditis elegans hom ...... DNA double-strand break repair
@ast
The Caenorhabditis elegans hom ...... DNA double-strand break repair
@en
The Caenorhabditis elegans hom ...... DNA double-strand break repair
@nl
prefLabel
The Caenorhabditis elegans hom ...... DNA double-strand break repair
@ast
The Caenorhabditis elegans hom ...... DNA double-strand break repair
@en
The Caenorhabditis elegans hom ...... DNA double-strand break repair
@nl
P2093
P2860
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The Caenorhabditis elegans hom ...... DNA double-strand break repair
@en
P2093
Alasdair Freeman
David M J Lilley
Julie Hall
Shawn Ahmed
P2860
P304
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10.1371/JOURNAL.PGEN.1001025
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P577
2010-07-15T00:00:00Z