The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor - Test2 - elhamkhani - TriplyDB

The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

http://www.wikidata.org/entity/Q28475670

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New insights into the aryl hydrocarbon receptor as a modulator of host responses to infection The Aryl Hydrocarbon Receptor: A Key Bridging Molecule of External and Internal Chemical Signals Anti-androgen flutamide suppresses hepatocellular carcinoma cell proliferation via the aryl hydrocarbon receptor mediated induction of transforming growth factor-β1 Access Path to the Ligand Binding Pocket May Play a Role in Xenobiotics Selection by AhR The aryl hydrocarbon receptor is required for induction of p21cip1/waf1 expression and growth inhibition by SU5416 in hepatoma cells.The aryl hydrocarbon receptor mediates raloxifene-induced apoptosis in estrogen receptor-negative hepatoma and breast cancer cells.AHR2 mutant reveals functional diversity of aryl hydrocarbon receptors in zebrafish The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells.A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain Transcriptome Analysis Reveals Novel Entry Mechanisms and a Central Role of SRC in Host Defense during High Multiplicity Mycobacterial Infection Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease.Potential protective mechanisms of aryl hydrocarbon receptor (AHR) signaling in benign prostatic hyperplasia Aryl hydrocarbon receptor ligands in cancer: friend and foe.Leflunomide Induces Pulmonary and Hepatic CYP1A Enzymes via Aryl Hydrocarbon Receptor.Aryl hydrocarbon receptor (AHR)-active pharmaceuticals are selective AHR modulators in MDA-MB-468 and BT474 breast cancer cells.Comparative analysis of homology models of the AH receptor ligand binding domain: verification of structure-function predictions by site-directed mutagenesis of a nonfunctional receptor.Inhibition of hepatic cytochrome P450 enzymes and sodium/bile acid cotransporter exacerbates leflunomide-induced hepatotoxicity Ligand promiscuity of aryl hydrocarbon receptor agonists and antagonists revealed by site-directed mutagenesis.Leflunomide: dermatologic perspective.Aryl hydrocarbon receptor and experimental autoimmune arthritis.The aryl hydrocarbon receptor: a review of its role in the physiology and pathology of the integument and its relationship to the tryptophan metabolism The emerging role of aryl hydrocarbon receptor in the activation and differentiation of Th17 cells.Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway.A redox-mediated Kemp eliminase.From Leflunomide to Teriflunomide: Drug Development and Immunosuppressive Oral Drugs in the Treatment of Multiple Sclerosis.Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis.Leflunomide suppresses growth in human medullary thyroid cancer cells.Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target.Genomic, Lipidomic and Metabolomic Analysis of Cyclooxygenase-null Cells: Eicosanoid Storm, Cross Talk, and Compensation by COX-1.Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells.Wnt-signaling enhances neural crest migration of melanoma cells and induces an invasive phenotype.Leflunomide induces NAD(P)H quinone dehydrogenase 1 enzyme via the aryl hydrocarbon receptor in neonatal mice.

P2860

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P2860

The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

http://www.wikidata.org/entity/Q28475670

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

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The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

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The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

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type

label

The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

@ast

The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

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The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

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prefLabel

The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

@ast

The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

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The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

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The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

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Daniel C Koch

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David Farrer

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Edmond F O'Donnell

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Lijoy K Mathew

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Nancy I Kerkvliet

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Prasad R Kopparapu

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Robert L Tanguay

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Siva Kumar Kolluri

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Sumitra Sengupta

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William H Bisson

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P2860

Role of the aryl hydrocarbon receptor in cell cycle regulation

A short Nur77-derived peptide converts Bcl-2 from a protector to a killer

The aryl hydrocarbon receptor: a perspective on potential roles in the immune system

Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3

Determination of lymphocyte division by flow cytometry

Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor

Cloning of a factor required for activity of the Ah (dioxin) receptor

Recruitment of thyroid hormone receptor/retinoblastoma-interacting protein 230 by the aryl hydrocarbon receptor nuclear translocator is required for the transcriptional response to both dioxin and hypoxia

p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells

The aryl hydrocarbon receptor complex and the control of gene expression

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10.1371/JOURNAL.PONE.0013128

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10

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5

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Katerine S Saili

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2010-10-01T00:00:00Z

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47459979

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20957046

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