Structure of protein interaction networks and their implications on drug design
about
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewNetwork connectivity during mergers and growth: Optimizing the addition of a moduleSystems Biology for Smart Crops and Agricultural Innovation: Filling the Gaps between Genotype and Phenotype for Complex Traits Linked with Robust Agricultural Productivity and SustainabilityNetwork neighbors of drug targets contribute to drug side-effect similarityTarget essentiality and centrality characterize drug side effectsRobustness and evolvability of the human signaling networkDistinctive Behaviors of Druggable Proteins in Cellular NetworksInferring gene dependency network specific to phenotypic alteration based on gene expression data and clinical information of breast cancerSynSysNet: integration of experimental data on synaptic protein-protein interactions with drug-target relationsEffects of protein interaction data integration, representation and reliability on the use of network properties for drug target prediction.VAN: an R package for identifying biologically perturbed networks via differential variability analysisA computational model to predict bone metastasis in breast cancer by integrating the dysregulated pathways.Systems analysis of inflammatory bowel disease based on comprehensive gene information.Topology of molecular interaction networks.Dissecting the human protein-protein interaction network via phylogenetic decomposition.Intercellular interactomics of human brain endothelial cells and th17 lymphocytes: a novel strategy for identifying therapeutic targets of CNS inflammationDrug target prediction based on the herbs components: the study on the multitargets pharmacological mechanism of qishenkeli acting on the coronary heart diseaseSystems biology of fungal infection.Diverse array-designed modes of combination therapies in Fangjiomics.Cardioprotective Effects of Qishenyiqi Mediated by Angiotensin II Type 1 Receptor Blockade and Enhancing Angiotensin-Converting Enzyme 2Evolutionary Model Selection and Parameter Estimation for Protein-Protein Interaction Network Based on Differential Evolution Algorithm.Functional analysis of long intergenic non-coding RNAs in phosphate-starved rice using competing endogenous RNA network.Proteome-wide prediction of self-interacting proteins based on multiple properties.Modeling and analysis of retinoic acid induced differentiation of uncommitted precursor cellsVisualization of the interactome: what are we looking at?Approaches to Ras signaling modulation and treatment of Ras-dependent disorders: a patent review (2007--present).A conceptual review on systems biology in health and diseases: from biological networks to modern therapeutics.Biological networks and drug discovery--where do we stand?Cross-Disciplinary Network Comparison: Matchmaking Between Hairballs.Identification of drug-target interaction from interactome network with 'guilt-by-association' principle and topology features.Targets of drugs are generally, and targets of drugs having side effects are specifically good spreaders of human interactome perturbationsEvolutionary analysis and interaction prediction for protein-protein interaction network in geometric spaceInferring multi-target QSAR models with taxonomy-based multi-task learning.Integrated gene co-expression network analysis in the growth phase of Mycobacterium tuberculosis reveals new potential drug targets.gene2drug: a Computational Tool for Pathway-based Rational Drug Repositioning.Identification of prognostic signature in cancer based on DNA methylation interaction network.Building protein-protein interaction networks for Leishmania species through protein structural information.Disturbed protein-protein interaction networks in metastatic melanoma are associated with worse prognosis and increased functional mutation burden.Challenges in the design of multitarget drugs against multifactorial pathologies: a new life for medicinal chemistry?
P2860
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P2860
Structure of protein interaction networks and their implications on drug design
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structure of protein interaction networks and their implications on drug design
@ast
Structure of protein interaction networks and their implications on drug design
@en
Structure of protein interaction networks and their implications on drug design
@nl
type
label
Structure of protein interaction networks and their implications on drug design
@ast
Structure of protein interaction networks and their implications on drug design
@en
Structure of protein interaction networks and their implications on drug design
@nl
prefLabel
Structure of protein interaction networks and their implications on drug design
@ast
Structure of protein interaction networks and their implications on drug design
@en
Structure of protein interaction networks and their implications on drug design
@nl
P2093
P2860
P1476
Structure of protein interaction networks and their implications on drug design
@en
P2093
Hiroaki Kitano
Hiroshi Tanaka
Takeshi Hase
Yasuhiro Suzuki
P2860
P304
P356
10.1371/JOURNAL.PCBI.1000550
P407
P50
P577
2009-10-01T00:00:00Z