Episomal viral cDNAs identify a reservoir that fuels viral rebound after treatment interruption and that contributes to treatment failure
about
Post-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virusQuantification of viral infection dynamics in animal experimentsPhosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytesAdvances in biosensing strategies for HIV-1 detection, diagnosis, and therapeutic monitoring.Highly divergent patterns of genetic diversity and evolution in proviral quasispecies from HIV controllers.High-throughput Characterization of HIV-1 Reservoir Reactivation Using a Single-Cell-in-Droplet PCR Assay.Rapid turnover of 2-LTR HIV-1 DNA during early stage of highly active antiretroviral therapy.Long-term antiretroviral treatment initiated at primary HIV-1 infection affects the size, composition, and decay kinetics of the reservoir of HIV-1-infected CD4 T cellsIncorporating alternative splicing and mRNA editing into the genetic analysis of complex traits.HIV controllers with different viral load cutoff levels have distinct virologic and immunologic profiles.The role of unintegrated DNA in HIV infectionIntegrated and Total HIV-1 DNA Predict Ex Vivo Viral OutgrowthTh1/17 Polarization of CD4 T Cells Supports HIV-1 Persistence during Antiretroviral Therapy.Impact of a decade of successful antiretroviral therapy initiated at HIV-1 seroconversion on blood and rectal reservoirs.Concurrent measures of total and integrated HIV DNA monitor reservoirs and ongoing replication in eradication trialsThe role of HIV integration in viral persistence: no more whistling past the proviral graveyard.Peripheral T Follicular Helper Cells Are the Major HIV Reservoir within Central Memory CD4 T Cells in Peripheral Blood from Chronically HIV-Infected Individuals on Combination Antiretroviral Therapy.Long-term reduction in peripheral blood HIV type 1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantationCell-associated HIV RNA: a dynamic biomarker of viral persistence.Modelling HIV-1 2-LTR dynamics following raltegravir intensification.Short Intracellular HIV-1 Transcripts as Biomarkers of Residual Immune Activation in Patients on Antiretroviral TherapyLack of concordance between residual viremia and viral variants driving de novo infection of CD4(+) T cells on ART.How to best measure HIV reservoirs?Effects of raltegravir on 2-long terminal repeat circle junctions in HIV type 1 viremic and aviremic patientsAn HIV-1 replication pathway utilizing reverse transcription products that fail to integrate.Spatial modeling of HIV cryptic viremia and 2-LTR formation during raltegravir intensification.HIV-1 persistence in CD4+ T cells with stem cell-like properties.Potential strategies for an HIV infection cure.HIV reservoirs and strategies for eradication.Eliminating the HIV reservoir.Targeting HIV latency: resting memory T cells, hematopoietic progenitor cells and future directions.Analysis of multiple cell reservoirs expressing unspliced HIV-1 gag-pol mRNA in patients on antiretroviral therapyAccurate quantification of episomal HIV-1 two-long terminal repeat circles by use of optimized DNA isolation and droplet digital PCR.The Use of Ultra-Sensitive Molecular Assays in HIV Cure-Related Research.Next-generation sequencing analyses of the emergence and maintenance of mutations in CTL epitopes in HIV controllers with differential viremia controlHow to escape treatment
P2860
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P2860
Episomal viral cDNAs identify a reservoir that fuels viral rebound after treatment interruption and that contributes to treatment failure
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Episomal viral cDNAs identify ...... ntributes to treatment failure
@ast
Episomal viral cDNAs identify ...... ntributes to treatment failure
@en
Episomal viral cDNAs identify ...... ntributes to treatment failure
@nl
type
label
Episomal viral cDNAs identify ...... ntributes to treatment failure
@ast
Episomal viral cDNAs identify ...... ntributes to treatment failure
@en
Episomal viral cDNAs identify ...... ntributes to treatment failure
@nl
prefLabel
Episomal viral cDNAs identify ...... ntributes to treatment failure
@ast
Episomal viral cDNAs identify ...... ntributes to treatment failure
@en
Episomal viral cDNAs identify ...... ntributes to treatment failure
@nl
P2093
P2860
P3181
P1433
P1476
Episomal viral cDNAs identify ...... ntributes to treatment failure
@en
P2093
Daniel R Kuritzkes
Dunja Z Babic
Mario Stevenson
Mark Sharkey
Roy Gulick
Thomas Greenough
P2860
P304
P3181
P356
10.1371/JOURNAL.PPAT.1001303
P407
P577
2011-02-01T00:00:00Z