Inhibitors of Helicobacter pylori protease HtrA found by 'virtual ligand' screening combat bacterial invasion of epithelia
about
A role for altered phagosome maturation in the long-term persistence of Helicobacter pylori infectionEnteric bacterial proteases in inflammatory bowel disease- pathophysiology and clinical implicationsAutoSite: an automated approach for pseudo-ligands prediction-from ligand-binding sites identification to predicting key ligand atoms.Immunosuppressive small molecule discovered by structure-based virtual screening for inhibitors of protein-protein interactions.Structure-based design of small-molecule protein-protein interaction modulators: the story so far.Fragment-Based De Novo Design Reveals a Small-Molecule Inhibitor of Helicobacter Pylori HtrA.Identification of E-cadherin signature motifs functioning as cleavage sites for Helicobacter pylori HtrAInhibiting Helicobacter pylori HtrA protease by addressing a computationally predicted allosteric ligand binding site.CtHtrA: the lynchpin of the chlamydial surface and a promising therapeutic target.Proteases in Mycobacterium tuberculosis pathogenesis: potential as drug targets.Bacterial proteases, untapped antimicrobial drug targets.Exploiting the Gastric Epithelial Barrier: Helicobacter pylori's Attack on Tight and Adherens Junctions.Proteolysis in Helicobacter pylori-Induced Gastric Cancer.The salt-sensitive structure and zinc inhibition of Borrelia burgdorferi protease BbHtrA.The stability and activity of recombinant Helicobacter pylori HtrA under stress conditions.Bacterial serine protease HtrA as a promising new target for antimicrobial therapy?Distinct roles of secreted HtrA proteases from gram-negative pathogens in cleaving the junctional protein and tumor suppressor E-cadherin.Development of purely structure-based pharmacophores for the topoisomerase I-DNA-ligand binding pocket.Proteases and protease inhibitors in infectious diseases.Decoys Selection in Benchmarking Datasets: Overview and Perspectives.From the protein's perspective: the benefits and challenges of protein structure-based pharmacophore modelingFrom Virtual Screening to Bioactive Compounds by Visualizing and Clustering of Chemical Space
P2860
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P2860
Inhibitors of Helicobacter pylori protease HtrA found by 'virtual ligand' screening combat bacterial invasion of epithelia
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Inhibitors of Helicobacter pyl ...... acterial invasion of epithelia
@ast
Inhibitors of Helicobacter pyl ...... acterial invasion of epithelia
@en
Inhibitors of Helicobacter pyl ...... acterial invasion of epithelia
@nl
type
label
Inhibitors of Helicobacter pyl ...... acterial invasion of epithelia
@ast
Inhibitors of Helicobacter pyl ...... acterial invasion of epithelia
@en
Inhibitors of Helicobacter pyl ...... acterial invasion of epithelia
@nl
prefLabel
Inhibitors of Helicobacter pyl ...... acterial invasion of epithelia
@ast
Inhibitors of Helicobacter pyl ...... acterial invasion of epithelia
@en
Inhibitors of Helicobacter pyl ...... acterial invasion of epithelia
@nl
P2093
P2860
P1433
P1476
Inhibitors of Helicobacter pyl ...... acterial invasion of epithelia
@en
P2093
Benjamin Hoy
Martin Löwer
Petra Schneider
Tim Geppert
P2860
P304
P356
10.1371/JOURNAL.PONE.0017986
P407
P577
2011-03-31T00:00:00Z