Single cell genome amplification accelerates identification of the apratoxin biosynthetic pathway from a complex microbial assemblage
about
SPAdes: a new genome assembly algorithm and its applications to single-cell sequencingDiscovery Strategies of Bioactive Compounds Synthesized by Nonribosomal Peptide Synthetases and Type-I Polyketide Synthases Derived from Marine Microbiomes.Lessons from the past and charting the future of marine natural products drug discovery and chemical biologyBiocatalysts and small molecule products from metagenomic studiesBayesHammer: Bayesian clustering for error correction in single-cell sequencingEmerging concepts promising new horizons for marine biodiscovery and synthetic biologyMining the metabiome: identifying novel natural products from microbial communities.Insights from the sea: structural biology of marine polyketide synthasesThe future is now: single-cell genomics of bacteria and archaeaGenomic insights into the marine sponge microbiome.An environmental bacterial taxon with a large and distinct metabolic repertoire.Metagenomic small molecule discovery methods.Phylogenetic inferences reveal a large extent of novel biodiversity in chemically rich tropical marine cyanobacteriaMeta-omic characterization of prokaryotic gene clusters for natural product biosynthesis.Natural product biosyntheses in cyanobacteria: A treasure trove of unique enzymes.Dung-inhabiting fungi: a potential reservoir of novel secondary metabolites for the control of plant pathogens.Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria.Cyclization of fungal nonribosomal peptides by a terminal condensation-like domainApratoxin H and apratoxin A sulfoxide from the Red Sea cyanobacterium Moorea producens.Biosynthetic origin of butyrolactol A, an antifungal polyketide produced by a marine-derived Streptomyces.Bioactive compounds synthesized by non-ribosomal peptide synthetases and type-I polyketide synthases discovered through genome-mining and metagenomics.Genomic sequencing of uncultured microorganisms from single cells.Bringing microbial interactions to light using imaging mass spectrometry.Challenges of metagenomics and single-cell genomics approaches for exploring cyanobacterial diversity.The use of evolutionary approaches to understand single cell genomes.Genome sequence and composition of a tolyporphin-producing cyanobacterium-microbial community.Unique marine derived cyanobacterial biosynthetic genes for chemical diversity.Comparative genomics uncovers the prolific and distinctive metabolic potential of the cyanobacterial genus Moorea.Mining prokaryotes for antimicrobial compounds: from diversity to function.Phylogenetic analysis of cultivation-resistant terrestrial cyanobacteria with massive sheaths (Stigonema spp. and Petalonema alatum, Nostocales, Cyanobacteria) using single-cell and filament sequencing of environmental samples.Application of genomic technologies to measure and monitor antibiotic resistance in animals.Impact of nitrogen sources on gene expression and toxin production in the diazotroph Cylindrospermopsis raciborskii CS-505 and non-diazotroph Raphidiopsis brookii D9.On the origin of 3-methylglutaconic acid in disorders of mitochondrial energy metabolismGenomic mining for novel FADH₂-dependent halogenases in marine sponge-associated microbial consortia.The Phormidolide Biosynthetic Gene Cluster: A trans-AT PKS Pathway Encoding a Toxic Macrocyclic Polyketide.Evaluation of Streptomyces coelicolor A3(2) as a heterologous expression host for the cyanobacterial protein kinase C activator lyngbyatoxin A.Beyond the bulk: disclosing the life of single microbial cells.A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit.Combined genetic and bioactivity-based prioritization leads to the isolation of an endophyte-derived antimycobacterial compound.PKS-NRPS Enzymology and Structural Biology: Considerations in Protein Production.
P2860
Q24629733-3C04AAA0-9D2F-472A-B1E2-BDED0C865658Q26752366-23D2CA0C-0F3B-45B1-A804-07BE1E2FC81BQ26863108-21FBE0D6-8AF3-4197-801C-033D3D45E7E8Q27003608-690D2A84-C0A7-4405-8E98-1D0A8CC33594Q27496610-833AC26B-7A40-41CD-AB37-2F2ACD788F66Q28080553-136A906F-43F8-48B9-913F-CB2D69979F4AQ34228002-C83388F7-DCDD-4735-84B4-A792029E2316Q34267983-F1B3614E-0814-4EE6-907A-6A7F945D64A8Q34321477-7A70756C-972B-4C00-B793-F3A83540D7ADQ34355776-B1A4E2A7-2117-47EA-A955-CC9D9FC9C609Q34400837-2A9E7437-27FF-44F7-BF26-48B7516783A1Q34428178-C55CDDAA-DA14-465E-ABDF-38299EE3002CQ34547058-402AE555-BDB0-4AB1-883E-C33203E6A79EQ34753855-1EFEDDFE-CF6A-4F76-ADBA-47C01EA56D43Q35657440-D1E0B8D8-F2EC-4852-B411-51155B9AC9F7Q35867844-2899B06E-89BD-402E-A356-222B81EACBEFQ36377751-2580BF57-C8DD-41A1-9A00-E7D655DB244AQ36420193-29842FFD-4A25-4F2D-A8A1-84373E5E28FDQ37672660-402CF13D-6290-4830-ACED-E2C0A19C158BQ37707960-F01A5029-A56B-4C14-B3FF-D3BD14CF32DFQ38000475-8B681BA4-C151-416F-939E-2CEC10FBBED5Q38034380-E7ED7D3B-F045-4504-A66E-6B819182A9AEQ38180945-9A78ED7D-57C0-43E9-B2FC-F3B91FEEBE88Q38291035-C2530936-30D2-4164-8F90-BFF8EC828BE0Q38389938-F4EF4E4F-D098-4C1D-B408-0ABF18AC0A95Q38654389-8702B49A-3887-47A3-822D-FF337B704BE8Q38693793-059FC391-3DE8-4152-A96B-C431A1B6CC41Q38749943-70208887-53C5-4749-BF8C-F5DDF0060FDFQ38840658-92E012B3-5A2D-4D9A-A8AA-2238BF95557BQ38893970-3A251E06-3394-40DF-841A-2ADDCF6D8B5BQ39044602-403F7FD4-ABDD-4AB2-B133-9DDA5D4CB1E8Q41340786-5F15F750-7B64-4459-BD08-4F3D9C54A957Q41700092-DB0C4AEB-9A9E-4DBE-827E-4E0DD535F2D5Q42647136-2C5B4935-CFA5-4356-BE42-E199CD151FB9Q42764696-F991968E-22C0-4883-A80F-756E69D1D35DQ46123019-501D655B-3F3B-4AFC-9B37-A642841CBB11Q47446895-55B0DB69-AC98-4C70-A187-FDE89FEA074DQ47449403-7E116E80-2284-4E4B-83E3-4D1C41EE9C86Q47887667-96AEFC41-2FD5-4ACC-B341-69AC6FC929DFQ54201616-43C94586-DFCE-45AF-9712-7B89D40A0B10
P2860
Single cell genome amplification accelerates identification of the apratoxin biosynthetic pathway from a complex microbial assemblage
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Single cell genome amplificati ...... a complex microbial assemblage
@ast
Single cell genome amplificati ...... a complex microbial assemblage
@en
Single cell genome amplificati ...... a complex microbial assemblage
@nl
type
label
Single cell genome amplificati ...... a complex microbial assemblage
@ast
Single cell genome amplificati ...... a complex microbial assemblage
@en
Single cell genome amplificati ...... a complex microbial assemblage
@nl
prefLabel
Single cell genome amplificati ...... a complex microbial assemblage
@ast
Single cell genome amplificati ...... a complex microbial assemblage
@en
Single cell genome amplificati ...... a complex microbial assemblage
@nl
P2093
P2860
P3181
P1433
P1476
Single cell genome amplificati ...... a complex microbial assemblage
@en
P2093
Dumitru Brinza
Eduardo Esquenazi
Lena Gerwick
Pavel Pevzner
Pieter C Dorrestein
R Cameron Coates
Rashel V Grindberg
Roger Lasken
Thomas Ishoey
Wei-ting Liu
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0018565
P407
P577
2011-04-12T00:00:00Z