Positive selection for new disease mutations in the human germline: evidence from the heritable cancer syndrome multiple endocrine neoplasia type 2B
about
Sperm competition and the evolution of spermatogenesisSelfish spermatogonial selection: evidence from an immunohistochemical screen in testes of elderly menNew insights into the generation and role of de novo mutations in health and disease"Selfish spermatogonial selection": a novel mechanism for the association between advanced paternal age and neurodevelopmental disordersGenetic mosaics and the germ line lineageUpsetting the dogma: germline selection in human males.Disomy 21 in spermatozoa and the paternal origin of trisomy 21 Down syndrome.Estimating Exceptionally Rare Germline and Somatic Mutation Frequencies via Next Generation Sequencing.Visualizing the origins of selfish de novo mutations in individual seminiferous tubules of human testes.Age-dependent germline mosaicism of the most common noonan syndrome mutation shows the signature of germline selection.New evidence for positive selection helps explain the paternal age effect observed in achondroplasiaContributions of intrinsic mutation rate and selfish selection to levels of de novo HRAS mutations in the paternal germline.Cellular evidence for selfish spermatogonial selection in aged human testes.Thyroid C-Cell Biology and Oncogenic Transformation.Ultra-sensitive Sequencing Identifies High Prevalence of Clonal Hematopoiesis-Associated Mutations throughout Adult Life.Germline Stem Cell Competition, Mutation Hot Spots, Genetic Disorders, and Older Fathers.Positive Germline Selection in Pedigrees With Multiple Endocrine Neoplasia Type 2 Carrying V804M Mutation in the RET Gene.Cellular correlates of selfish spermatogonial selection.The paternal age at conception effect on offspring telomere length: mechanistic, comparative and adaptive perspectives.An alternative interpretation of cellular 'selfish spermatogonial selection'-clusters in the human testis indicates the need for 3-D-analyses.
P2860
Q27006997-9F4C64C1-1348-4D3E-A524-AB7997FAC976Q27325525-276C2DB2-2589-44C3-B109-95C4CB3B49CBQ28073446-4ED6975B-702C-49D6-9F51-73D33573D498Q28290020-0ECDCCE1-43FF-449A-A78E-15FFB7C91EE3Q28397586-73686604-F00B-4B77-9E8D-B693C5E97EE9Q34167957-42AE2190-A82A-4B54-9905-B3D11AE6F96EQ35984811-3EA829FE-977E-4706-BDB0-C0A3CFC0BFC9Q36061094-945EC385-9843-420A-9AA0-630C9629F523Q36659007-F774FF1F-6964-4111-9963-1F95F2B0000DQ36929566-2595622E-CAFA-4613-AB1E-ABA219257737Q37193908-4B952AA8-54D8-4F78-A548-A14C2641F702Q37395153-A6268B7C-7036-4E7A-BC5E-3CAEF8E7E23AQ38172901-DAF07AD8-1F0C-4206-8975-C265DA4CDCBDQ38614485-75ADF122-5D32-4923-9F83-DD24C55E26CCQ40150370-9F345EA6-6A08-4AB7-9B0B-8040F8734CFDQ40989489-E182A62B-87A1-4E7C-B526-8FBA6E108B80Q42286746-ED5F4A97-AE0E-44F7-A225-A1C93C0B93C9Q42763482-18ADFC11-DDAB-41DB-9E8C-C24DA9899F77Q51158138-7F53E2A3-94D7-4487-B6E8-F26360680399Q53171210-9A539C8E-655F-402E-920A-17BC21D6A006
P2860
Positive selection for new disease mutations in the human germline: evidence from the heritable cancer syndrome multiple endocrine neoplasia type 2B
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
name
Positive selection for new dis ...... le endocrine neoplasia type 2B
@ast
Positive selection for new dis ...... le endocrine neoplasia type 2B
@en
Positive selection for new dis ...... le endocrine neoplasia type 2B
@nl
type
label
Positive selection for new dis ...... le endocrine neoplasia type 2B
@ast
Positive selection for new dis ...... le endocrine neoplasia type 2B
@en
Positive selection for new dis ...... le endocrine neoplasia type 2B
@nl
prefLabel
Positive selection for new dis ...... le endocrine neoplasia type 2B
@ast
Positive selection for new dis ...... le endocrine neoplasia type 2B
@en
Positive selection for new dis ...... le endocrine neoplasia type 2B
@nl
P2093
P2860
P3181
P1433
P1476
Positive selection for new dis ...... le endocrine neoplasia type 2B
@en
P2093
Norman Arnheim
Peter Calabrese
Song-Ro Yoon
Soo-Kyung Choi
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1002420
P407
P577
2012-01-01T00:00:00Z