Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types
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Patterns of Chromosomal Aberrations in Solid TumorsHypothesis: Artifacts, Including Spurious Chimeric RNAs with a Short Homologous Sequence, Caused by Consecutive Reverse Transcriptions and Endogenous Random PrimersHeterogeneity of epidermal growth factor receptor signalling networks in glioblastomaPF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutationsTargeted Cancer Therapy: Vital Oncogenes and a New Molecular Genetic Paradigm for Cancer Initiation Progression and TreatmentExploration of the gene fusion landscape of glioblastoma using transcriptome sequencing and copy number dataLandscape of somatic mutations in 560 breast cancer whole-genome sequences.Molecular pathways: ROS1 fusion proteins in cancer.Seven novel probe systems for real-time PCR provide absolute single-base discrimination, higher signaling, and generic components.The landscape of kinase fusions in cancerIntegrative genomic and functional profiling of the pancreatic cancer genome.Chromatin states modify network motifs contributing to cell-specific functions.Fusion transcript loci share many genomic features with non-fusion loci.KAOS: a new automated computational method for the identification of overexpressed genes.ROS1 immunohistochemistry among major genotypes of non-small-cell lung cancerAnalyzing Somatic Genome Rearrangements in Human Cancers by Using Whole-Exome Sequencing.Palbociclib treatment of FLT3-ITD+ AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and PIM1 by CDK6.Tyrosine kinase gene rearrangements in epithelial malignancies.Detecting and targetting oncogenic fusion proteins in the genomic era.Recent Advances in Targeting ROS1 in Lung Cancer.Detection of ROS1 rearrangement in non-small cell lung cancer: current and future perspectives.Diverse, Biologically Relevant, and Targetable Gene Rearrangements in Triple-Negative Breast Cancer and Other Malignancies.ROS1 fusions in cancer: a review.CD44-SLC1A2 fusion transcripts in primary colorectal cancer.Pediatric T-cell acute lymphoblastic leukemia.ALK oncoproteins in atypical inflammatory myofibroblastic tumours: novel RRBP1-ALK fusions in epithelioid inflammatory myofibroblastic sarcoma.Gene and miRNA expression changes in squamous cell carcinoma of larynx and hypopharynx.Distinct distributions of genomic features of the 5' and 3' partners of coding somatic cancer gene fusions: arising mechanisms and functional implicationsFrequent miRNA-convergent fusion gene events in breast cancer.Compound clear cell sarcoma misdiagnosed as a Spitz nevus.EWSR1 Fusions With CREB Family Transcription Factors Define a Novel Myxoid Mesenchymal Tumor With Predilection for Intracranial Location.Immunohistochemical Detection of ROS1 Fusion.The rationale for druggability of CCDC6-tyrosine kinase fusions in lung cancer.miRNA-convergent gene fusions.Driver Fusions and Their Implications in the Development and Treatment of Human Cancers.Detection of specific gene rearrangements by fluorescence in situ hybridization in 16 cases of clear cell sarcoma of soft tissue and 6 cases of clear cell sarcoma-like gastrointestinal tumor
P2860
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P1343
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P2860
Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types
description
2013 nî lūn-bûn
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2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Breakpoint analysis of transcr ...... ng multiple human cancer types
@ast
Breakpoint analysis of transcr ...... ng multiple human cancer types
@en
Breakpoint analysis of transcr ...... ng multiple human cancer types
@nl
type
label
Breakpoint analysis of transcr ...... ng multiple human cancer types
@ast
Breakpoint analysis of transcr ...... ng multiple human cancer types
@en
Breakpoint analysis of transcr ...... ng multiple human cancer types
@nl
prefLabel
Breakpoint analysis of transcr ...... ng multiple human cancer types
@ast
Breakpoint analysis of transcr ...... ng multiple human cancer types
@en
Breakpoint analysis of transcr ...... ng multiple human cancer types
@nl
P2093
P2860
P50
P3181
P1433
P1476
Breakpoint analysis of transcr ...... ng multiple human cancer types
@en
P2093
A Hunter Shain
Albert J Wong
Andrew D Forster
Catherine A Del Vecchio
Craig P Giacomini
Everett Lai
Jay Balagtas
Kelli D Montgomery
Marilyn M Giacomini
Nicole Clarke
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1003464
P407
P577
2013-04-01T00:00:00Z