Cdx2 determines the fate of postnatal intestinal endoderm
about
Stomach development, stem cells and diseasehTERT promotes gastric intestinal metaplasia by upregulating CDX2 via NF-κB signaling pathway.Transcriptional regulation of the intestinal nuclear bile acid farnesoid X receptor (FXR) by the caudal-related homeobox 2 (CDX2).Cdx1 and Cdx2 exhibit transcriptional specificity in the intestine.Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2.Maternal-zygotic knockout reveals a critical role of Cdx2 in the morula to blastocyst transition.Transcription factors GATA4 and HNF4A control distinct aspects of intestinal homeostasis in conjunction with transcription factor CDX2.CDX2 protein expression compared to alcian blue staining in the evaluation of esophageal intestinal metaplasia.Intestinal Commitment and Maturation of Human Pluripotent Stem Cells Is Independent of Exogenous FGF4 and R-spondin1GATA4 represses an ileal program of gene expression in the proximal small intestine by inhibiting the acetylation of histone H3, lysine 27.Intestinal master transcription factor CDX2 controls chromatin access for partner transcription factor binding.CDX2 regulation by the RNA-binding protein MEX3A: impact on intestinal differentiation and stemness.CDX2 increases SLC7A7 expression and proliferation of pig intestinal epithelial cells.Silencing of the EPHB3 tumor-suppressor gene in human colorectal cancer through decommissioning of a transcriptional enhancer.Barrett's esophagus: cancer and molecular biology.Achaete scute-like 2 suppresses CDX2 expression and inhibits intestinal neoplastic epithelial cell differentiation.Extending the functions of the homeotic transcription factor Cdx2 in the digestive system through nontranscriptional activities.Ketogenesis contributes to intestinal cell differentiation.Distinct Processes and Transcriptional Targets Underlie CDX2 Requirements in Intestinal Stem Cells and Differentiated Villus Cells.Increasing the oxygen load by treatment with myo-inositol trispyrophosphate reduces growth of colon cancer and modulates the intestine homeobox gene Cdx2.SNAIL1 combines competitive displacement of ASCL2 and epigenetic mechanisms to rapidly silence the EPHB3 tumor suppressor in colorectal cancer.SOX2 redirects the developmental fate of the intestinal epithelium toward a premature gastric phenotype.CDX2 Stimulates the Proliferation of Porcine Intestinal Epithelial Cells by Activating the mTORC1 and Wnt/β-Catenin Signaling Pathways.Degree of Tissue Differentiation Dictates Susceptibility to BRAF-Driven Colorectal Cancer.Generation of stomach tissue from mouse embryonic stem cells.Fine-tuning and autoregulation of the intestinal determinant and tumor suppressor homeobox gene CDX2 by alternative splicing.Metaplastic Cdx2-depleted cells can be very disruptive neighbors.The Cdx2 homeobox gene suppresses intestinal tumorigenesis through non-cell-autonomous mechanisms.Transcription factor-dependent 'anti-repressive' mammalian enhancers exclude H3K27me3 from extended genomic domains.Pyloric metaplasia, pseudopyloric metaplasia, ulcer-associated cell lineage and spasmolytic polypeptide-expressing metaplasia: reparative lineages in the gastrointestinal mucosa.Moving towards totipotency without a single miR-acle.Developmental biology. Regional identity of gut stem cells--one gene to rule them all.Chromatin de-condensation by switching substrate elasticity
P2860
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P2860
Cdx2 determines the fate of postnatal intestinal endoderm
description
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
@ast
im Februar 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2012/02/01)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd op 2012/02/01)
@nl
наукова стаття, опублікована в лютому 2012
@uk
مقالة علمية (نشرت في فبراير 2012)
@ar
name
Cdx2 determines the fate of postnatal intestinal endoderm
@ast
Cdx2 determines the fate of postnatal intestinal endoderm
@en
Cdx2 determines the fate of postnatal intestinal endoderm
@nl
type
label
Cdx2 determines the fate of postnatal intestinal endoderm
@ast
Cdx2 determines the fate of postnatal intestinal endoderm
@en
Cdx2 determines the fate of postnatal intestinal endoderm
@nl
prefLabel
Cdx2 determines the fate of postnatal intestinal endoderm
@ast
Cdx2 determines the fate of postnatal intestinal endoderm
@en
Cdx2 determines the fate of postnatal intestinal endoderm
@nl
P2093
P2860
P50
P356
P1433
P1476
Cdx2 determines the fate of postnatal intestinal endoderm
@en
P2093
Catrin A. Pritchard
Doug J. Winton
Emma J. Stringer
Felix Beck
Hans Clevers
Jacqueline Deschamps
Nicholas A. Wright
Nick Barker
Thoueiba Saandi
Toshiro Sato
P2860
P304
P356
10.1242/DEV.070722
P407
P577
2012-02-01T00:00:00Z