Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice
about
Regenerative Therapy of Type 1 Diabetes Mellitus: From Pancreatic Islet Transplantation to Mesenchymal Stem CellsSusceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase.Glucolipotoxicity of the pancreatic beta cell.High glucose aggravates the detrimental effects of pancreatic stellate cells on Beta-cell functionMafA is required for postnatal proliferation of pancreatic β-cells.Chronic glucolipotoxic conditions in pancreatic islets impair insulin secretion due to dysregulated calcium dynamics, glucose responsiveness and mitochondrial activity.Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice.The Generation of Insulin Producing Cells from Human Mesenchymal Stem Cells by MiR-375 and Anti-MiR-9.Islet Stellate Cells Isolated from Fibrotic Islet of Goto-Kakizaki Rats Affect Biological Behavior of Beta-Cell.Glucolipotoxicity: fuel excess and beta-cell dysfunction.Increase of Calcium Sensing Receptor Expression Is Related to Compensatory Insulin Secretion during Aging in Mice.Novel aspects of the molecular mechanisms controlling insulin secretion.SREBPs: physiology and pathophysiology of the SREBP family.Rab27 effectors, pleiotropic regulators in secretory pathways.Cyclosporin and tacrolimus impair insulin secretion and transcriptional regulation in INS-1E beta-cells.Novel genes in cell cycle control and lipid metabolism with dynamically regulated binding sites for sterol regulatory element-binding protein 1 and RNA polymerase II in HepG2 cells detected by chromatin immunoprecipitation with microarray detection.Developmental and extrahepatic physiological functions of SREBP pathway genes in mice.Preferential reduction of beta cells derived from Pax6-MafB pathway in MafB deficient mice.Expression of MafA in pancreatic progenitors is detrimental for pancreatic development.Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets.Toxicity beyond the lung: connecting PM2.5, inflammation, and diabetesSirt1 and mir-9 expression is regulated during glucose-stimulated insulin secretion in pancreatic β-islets.Age-dependent preferential dense-core vesicle exocytosis in neuroendocrine cells revealed by newly developed monomeric fluorescent timer protein.Cholesterol accumulation and diabetes in pancreatic beta-cell-specific SREBP-2 transgenic mice: a new model for lipotoxicity.Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men.SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology.
P2860
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P2860
Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice
description
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
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im August 2006 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2006/08/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/08/01)
@nl
наукова стаття, опублікована в серпні 2006
@uk
مقالة علمية (نشرت في أغسطس 2006)
@ar
name
Granuphilin is activated by SR ...... lin secretion in diabetic mice
@ast
Granuphilin is activated by SR ...... lin secretion in diabetic mice
@en
Granuphilin is activated by SR ...... lin secretion in diabetic mice
@nl
type
label
Granuphilin is activated by SR ...... lin secretion in diabetic mice
@ast
Granuphilin is activated by SR ...... lin secretion in diabetic mice
@en
Granuphilin is activated by SR ...... lin secretion in diabetic mice
@nl
prefLabel
Granuphilin is activated by SR ...... lin secretion in diabetic mice
@ast
Granuphilin is activated by SR ...... lin secretion in diabetic mice
@en
Granuphilin is activated by SR ...... lin secretion in diabetic mice
@nl
P2093
P50
P921
P3181
P1433
P1476
Granuphilin is activated by SR ...... lin secretion in diabetic mice
@en
P2093
Akimitsu Takahashi
Hideo Toyoshima
Hiroaki Suzuki
Hiroshi Gomi
Hitoshi Shimano
Mayumi Ishikawa
Nobuhiro Yamada
Satoru Takahashi
Shin Kumadaki
Takashi Matsuzaka
P304
P3181
P356
10.1016/J.CMET.2006.06.009
P577
2006-08-01T00:00:00Z