The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives
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Early acquisition of neural crest competence during hESCs neuralizationAsymmetrical distribution of non-conserved regulatory sequences at PHOX2B is reflected at the ENCODE loci and illuminates a possible genome-wide trendPHOX2B regulates its own expression by a transcriptional auto-regulatory mechanismLate-emigrating neural crest cells in the roof plate are restricted to a sensory fate by GDF7.The TLX2 homeobox gene is a transcriptional target of PHOX2B in neural-crest-derived cellsAn ancestral variant of Secretogranin II confers regulation by PHOX2 transcription factors and association with hypertensionGenome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesisDivergent functions of the proneural genes Mash1 and Ngn2 in the specification of neuronal subtype identityEnteric nervous system development: migration, differentiation, and diseaseMaintenance of postmitotic neuronal cell identityMeis3 is required for neural crest invasion of the gut during zebrafish enteric nervous system development.Microarray Analysis Reveals Increased Transcriptional Repression and Reduced Metabolic Activity but Not Major Changes in the Core Apoptotic Machinery during Maturation of Sympathetic Neurons.Distinct neuroblastoma-associated alterations of PHOX2B impair sympathetic neuronal differentiation in zebrafish modelsThe zebrafish as a model for studying neuroblastomaThe homeodomain protein Arix promotes protein kinase A-dependent activation of the dopamine beta-hydroxylase promoter through multiple elements and interaction with the coactivator cAMP-response element-binding protein-binding proteinThe paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation statusThe GDNF family: signalling, biological functions and therapeutic valueEngineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous systemPediatric disorders with autonomic dysfunction: what role for PHOX2B?PHOX2B immunolocalization of the candidate human retrotrapezoid nucleusMolecular pathogenesis of peripheral neuroblastic tumorsThe role of GDNF family ligand signalling in the differentiation of sympathetic and dorsal root ganglion neuronsFormation of brainstem (nor)adrenergic centers and first-order relay visceral sensory neurons is dependent on homeodomain protein Rnx/Tlx3Ascl1/Mash1 is required for the development of central serotonergic neuronsFunctional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channelsEya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodesPPARĪ³ in vagal neurons regulates high-fat diet induced thermogenesisHand2 determines the noradrenergic phenotype in the mouse sympathetic nervous systemBMP signaling regulates sympathetic nervous system development through Smad4-dependent and -independent pathwaysHes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain.Idiopathic weight reduction in mice deficient in the high-mobility-group transcription factor Sox8Age-associated changes in mRNA levels of Phox2, norepinephrine transporter and dopamine beta-hydroxylase in the locus coeruleus and adrenal glands of ratsZENON, a novel POZ Kruppel-like DNA binding protein associated with differentiation and/or survival of late postmitotic neuronsReciprocal gene replacements reveal unique functions for Phox2 genes during neural differentiation.The basic helix-loop-helix factor Hand 2 regulates autonomic nervous system developmentNeonatal lethality, dwarfism, and abnormal brain development in Dmbx1 mutant miceFrizzled3 is required for neurogenesis and target innervation during sympathetic nervous system developmentGenome-wide linkage identifies novel modifier loci of aganglionosis in the Sox10Dom model of Hirschsprung diseaseExpression of Ret-, p75(NTR)-, Phox2a-, Phox2b-, and tyrosine hydroxylase-immunoreactivity by undifferentiated neural crest-derived cells and different classes of enteric neurons in the embryonic mouse gutThe Hlx homeobox transcription factor is required early in enteric nervous system development
P2860
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P2860
The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives
description
1999 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« ÕÕ”ÕµÕ«Õ½Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕøÖÕ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ ÕµÖ
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@hyw
1999 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Õ“Õ”ÕµÕ«Õ½Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
article publiƩ dans la revue scientifique Nature
@fr
artĆculu cientĆficu espublizĆ”u en 1999
@ast
scientific journal article
@en
vedeckĆ½ ÄlĆ”nok (publikovanĆ½ 1999/05/27)
@sk
vÄdeckĆ½ ÄlĆ”nek publikovanĆ½ v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/05/27)
@nl
Š½Š°ŃŠŗŠ¾Š²Š° ŃŃŠ°ŃŃŃ, Š¾ŠæŃŠ±Š»ŃŠŗŠ¾Š²Š°Š½Š° Š² ŃŃŠ°Š²Š½Ń 1999
@uk
Ł
ŁŲ§ŁŲ© Ų¹ŁŁ
ŁŲ© (ŁŲ“Ų±ŲŖ ŁŁ 27-5-1999)
@ar
name
The homeobox gene Phox2b is es ...... nomic neural crest derivatives
@ast
The homeobox gene Phox2b is es ...... nomic neural crest derivatives
@en
The homeobox gene Phox2b is es ...... nomic neural crest derivatives
@nl
type
label
The homeobox gene Phox2b is es ...... nomic neural crest derivatives
@ast
The homeobox gene Phox2b is es ...... nomic neural crest derivatives
@en
The homeobox gene Phox2b is es ...... nomic neural crest derivatives
@nl
prefLabel
The homeobox gene Phox2b is es ...... nomic neural crest derivatives
@ast
The homeobox gene Phox2b is es ...... nomic neural crest derivatives
@en
The homeobox gene Phox2b is es ...... nomic neural crest derivatives
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
The homeobox gene Phox2b is es ...... nomic neural crest derivatives
@en
P2093
P2860
P2888
P304
P3181
P356
10.1038/20700
P407
P577
1999-05-01T00:00:00Z
P6179
1007292845