about
Atypical angiopoietin-like protein that regulates ANGPTL3Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytesThe ANGPTL3-4-8 model, a molecular mechanism for triglyceride traffickingThe role of ANGPTL3 in controlling lipoprotein metabolismAngiopoietin-like protein 3 inhibits lipoprotein lipase activity through enhancing its cleavage by proprotein convertasesExome sequencing, ANGPTL3 mutations, and familial combined hypolipidemiaSILAC-MS Based Characterization of LPS and Resveratrol Induced Changes in Adipocyte Proteomics - Resveratrol as Ameliorating Factor on LPS Induced ChangesVertebrate endothelial lipase: comparative studies of an ancient gene and protein in vertebrate evolutionAngiopoietin-Like Proteins: A Comprehensive LookIdentification of the active form of endothelial lipase, a homodimer in a head-to-tail conformation.Metabolic Syndrome Modulates Association between Endothelial Lipase and Lipid/Lipoprotein Plasma Levels in Acute Heart Failure Patients.O-glycosylation modulates proprotein convertase activation of angiopoietin-like protein 3: possible role of polypeptide GalNAc-transferase-2 in regulation of concentrations of plasma lipidsGenetic determinants of inherited susceptibility to hypercholesterolemia - a comprehensive literature review.Genetic variation at the proprotein convertase subtilisin/kexin type 5 gene modulates high-density lipoprotein cholesterol levelsProprotein convertases in high-density lipoprotein metabolism.Role of hepatic lipase and endothelial lipase in high-density lipoprotein-mediated reverse cholesterol transport.Proteolytic processing of angiopoietin-like protein 4 by proprotein convertases modulates its inhibitory effects on lipoprotein lipase activity.Reduction of circulating PCSK9 and LDL-C levels by liver-specific knockdown of HNF1α in normolipidemic mice.Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion.ANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys.Dense genotyping of candidate gene loci identifies variants associated with high-density lipoprotein cholesterol.Regulation of reverse cholesterol transport - a comprehensive appraisal of available animal studies.Hepatic S1P deficiency lowers plasma cholesterol levels in apoB-containing lipoproteins when LDLR function is compromised.Measurement of the phospholipase activity of endothelial lipase in mouse plasma.Hydrolysis products generated by lipoprotein lipase and endothelial lipase differentially impact THP-1 macrophage cell signalling pathways.In vivo functions of the proprotein convertase PC5/6 during mouse development: Gdf11 is a likely substrate.Biochemistry and pathophysiology of intravascular and intracellular lipolysis.The Arg59Trp variant in ANGPTL8 (betatrophin) is associated with total and HDL-cholesterol in American Indians and Mexican Americans and differentially affects cleavage of ANGPTL3.Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans.Different relationship between ANGPTL3 and HDL components in female non-diabetic subjects and type-2 diabetic patients.HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver.Angiopoietin-like proteins 3, 4 and 8: regulating lipid metabolism and providing new hope for metabolic syndrome.miRNAs and High-Density Lipoprotein metabolism.Dual mechanisms for the fibrate-mediated repression of proprotein convertase subtilisin/kexin type 9.Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism.ANGPLT3: A novel modulator of lipid metabolism.Angiopoietin-like 3 in lipoprotein metabolism.Phospholipid transfer protein: its impact on lipoprotein homeostasis and atheroslcerosis.Prodomain of Furin Promotes Phospholipid Transfer Protein Proteasomal Degradation in Hepatocytes.PCSK9 as a therapeutic target of dyslipidemia
P2860
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P2860
description
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article scientifique
@fr
artículu científicu espublizáu en 2007
@ast
scientific journal article
@en
vedecký článok (publikovaný 2007/08/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/08/01)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована в серпні 2007
@uk
name
Hepatic proprotein convertases modulate HDL metabolism
@ast
Hepatic proprotein convertases modulate HDL metabolism
@en
Hepatic proprotein convertases modulate HDL metabolism
@nl
type
label
Hepatic proprotein convertases modulate HDL metabolism
@ast
Hepatic proprotein convertases modulate HDL metabolism
@en
Hepatic proprotein convertases modulate HDL metabolism
@nl
prefLabel
Hepatic proprotein convertases modulate HDL metabolism
@ast
Hepatic proprotein convertases modulate HDL metabolism
@en
Hepatic proprotein convertases modulate HDL metabolism
@nl
P2093
P2860
P3181
P1433
P1476
Hepatic proprotein convertases modulate HDL metabolism
@en
P2093
Daniel J. Rader
George H. Rothblat
Jane M. Glick
John S. Millar
Weijun Jin
P2860
P304
P3181
P356
10.1016/J.CMET.2007.07.009
P577
2007-08-01T00:00:00Z